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Too little or too much iodine may push immunity off balance

This narrative review finds that adequate iodine supports thyroid hormone signaling, leukocyte metabolism, antioxidant defenses, and antimicrobial activity in humans and domesticated mammals. Both deficiency and sustained excess may impair immunity or promote thyroid inflammation, but precise immune-specific intake thresholds remain uncertain.

27 Jul 2026

KAIST study opens a new avenue for treating intractable brain tumors

Researchers have uncovered a clue to why immune checkpoint inhibitors-cancer therapies that release the immune "brakes" exploited by tumors to evade attack-show limited efficacy in some brain tumors.

19 Jul 2026

Review highlights macrophages as key drivers of chronic transplant rejection

A comprehensive review led by Professors Malgorzata Kloc and Xian Chang Li at the Immunobiology and Transplant Science Center of Houston Methodist Hospital in the United States was published in Volume 2, article number 29 of the journal Immunity & Inflammation on June 30, 2026.

9 Jul 2026

Study compares different light therapies for treating Alzheimer's disease

The researchers treated 5‑month‑old 5xFAD mice – a model with aggressive amyloid deposition – with 810‑nm light (25 mW/cm² at the scalp, ~6.25 mW/cm² brain dose for CW, and half that for 40‑Hz due to 50% duty cycle) for 10 minutes daily over 37 days.

6 Jul 2026

Reversing macrophage metabolism may improve cancer immunotherapy outcomes

Tumor-associated macrophages (TAMs) are among the most abundant immune cells in the tumor microenvironment.

1 Jul 2026

Lipid nanoparticles enhance immune response against lung cancer

Researchers at the University of Arizona R. Ken Coit College of Pharmacy have developed a new strategy that helps the immune system recognize and attack lung cancer tumors more effectively.

25 Jun 2026

Study identifies fPRDM16 as target for age-related pulmonary fibrosis

A study published recently in Current Molecular Pharmacology has uncovered a key mechanism linking aging to persistent pulmonary fibrosis, identifying the transcriptional regulator fPRDM16 as a potential therapeutic target.

25 Jun 2026

Microbes trigger cell death to boost cancer immunotherapy effectiveness

Traditional cancer treatments like chemotherapy and radiotherapy can induce immunogenic cell death (ICD), but their efficacy is often limited by drug resistance, severe off-target toxicity, and immune-related adverse events.

24 Jun 2026

Scientists discover immune cell control switch to destroy fungal infections

Scientists at the University of East Anglia (UK) have contributed to discovering a "control switch" inside our immune cells that helps the body destroy dangerous fungal infections.

11 May 2026

Study links polyploid cancer cells to tumor invasion and spread

One of the biggest challenges in cancer research is understanding why some tumor cells become especially aggressive, invasive and resistant to treatment.

23 Apr 2026

Alzheimer’s monoclonal antibodies fail to deliver meaningful results

Despite reducing amyloid plaques, antibody treatments for Alzheimer's fail to improve cognition, highlighting critical gaps in current therapeutic approaches.

21 Apr 2026

Targeting glutamine metabolism enhances CAR-macrophage cancer therapy

Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function.

20 Apr 2026

Pen-strep treatment rewires mechanical sensing in immune cells

Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to their phenotypic polarization and immune function.

13 Mar 2026

Genetic switch MafB enables macrophages to reach full maturity and preserve organ health

Researchers at the University of Liège have identified a key genetic regulator that enables macrophages to reach full maturity and preserve the health of our organs.

26 Feb 2026

Unexpected behavior observed during interactions between immune cells and dying cells

Over the years, cell biology has built a detailed picture of how cells compartmentalize their internal functions. Central to this organization is the nucleus, which houses the genetic material and is separated from the cytoplasm by a robust nuclear envelope.

25 Feb 2026

Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

Researchers engineered CD4+ chimeric antigen receptor T cells targeting fibrillar amyloid beta and tested them in a mouse Alzheimer model. The preclinical study showed reduced amyloid pathology and altered neuroimmune responses, supporting CAR-T immunotherapy as a potential future Alzheimer strategy.

11 Feb 2026

Regulating microglial phagocytosis through immunotherapy could slow Parkinson's disease progression

By analyzing tissue from patients with Parkinson's disease, and animal and cellular models of the disease, a research team from the Institut de Neurociències of the UAB has shown that the main immune cells of the brain become reactive and overexpress certain receptors that promote the elimination of dopaminergic neurons, even when these neurons are still functional.

2 Feb 2026