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Cannabis-derived nanovesicles showed early antitumor potential in mice

Researchers developed a Cannabis sativa hairy root culture system that produced stable plant-derived nanovesicles capable of promoting dendritic cell maturation and activating T-cell responses through TLR2- and TLR4-associated signaling. Oral administration also restored selected immune responses in immunosuppressed mice and suppressed tumor growth in an E.G7 lymphoma model, providing preliminary evidence for their immunomodulatory and antitumor potential.

15 Sep 2026

New review challenges the eight-hour ancestral sleep myth

Everyone knows the number. Eight hours. It sits on wellness dashboards, on pediatric handouts, on the label of the melatonin bottle in the medicine cabinet.

25 Aug 2026

Gut microbial metabolites may shape vulnerability to stress-related mental disorders

Gut microbiome-derived metabolites may influence stress-related mental disorders through neural, immune, endocrine, and epigenetic pathways. Evidence is strongest for depression and preclinical models, while larger longitudinal human studies are needed to establish causality and clinical value.

20 Jul 2026

Fatty liver disease fuels aggressive metastatic colorectal cancer spread

Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most aggressive form of metastatic colorectal cancer.

1 Jul 2026

New genetic roadmap offers targeted treatment for rare inflammatory disorder

Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.

22 May 2026

Marigold flower as a sustainable plant protein for food innovation

Marigold flower proteins exhibit solubility, emulsifying, and antioxidant properties with potential applications in food formulation.

5 May 2026

Targeted diet helps reprogram aggressive neuroblastoma in mice

Researchers highlighted how an arginine- and proline-restricted diet combined with eflornithine reprogrammed MYCN-driven neuroblastoma in mice, pushing tumor cells out of the cell cycle and toward differentiation. The commentary argues that this metabolism-to-translation link could open a new path for testing targeted dietary strategies alongside cancer drugs in future clinical studies.

9 Apr 2026

Prickly pear may pack a surprising punch against metabolic syndrome

This narrative review examines how Opuntia ficus-indica fruit, or prickly pear, may help target multiple features of metabolic syndrome through its fiber, betalains, polyphenols, carotenoids, and other bioactive compounds. The authors conclude that the fruit shows promising mechanistic and preclinical potential, but stronger human trials are still needed before firm clinical claims can be made.

6 Apr 2026

MULTI-evolve accelerates protein engineering with machine learning

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.

19 Feb 2026

Review: Pathogenesis, diagnosis, and management of harlequin ichthyosis

Harlequin ichthyosis (HI) is a rare, severe genetic skin disorder caused by ABCA12 mutations, leading to defective lipid transport and loss of skin barrier function.

17 Feb 2026

Lower hinge of immunoglobulin G acts as a critical immune control hub

The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo.

31 Jan 2026

MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils

One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain. The more severe the clumping, the more advanced the disease is.

14 Jan 2026

New research identifies molecular pathways linking hot weather and preterm birth risk

An Emory University study, published Friday by Science Advances, provides the first evidence that exposure to higher temperatures during pregnancy is linked to specific biological changes in mothers that are also associated with preterm birth.

22 Nov 2025

Researchers develop a new approach for treating children with neuroblastoma

A research team from the University of Zurich and the University Children's Hospital Zurich has developed a new approach for treating children with malignant tumors of the nervous system.

21 Oct 2025

How gluten harms some people but helps others

New insights reveal gluten's health potential, highlighting beneficial peptides and innovative methods to enhance wheat safety for sensitive individuals.

3 Oct 2025

Molecular fingerprint predicts physical fitness in older adults

Could a simple blood test reveal how well someone is aging? A team of researchers led by Wolfram Weckwerth from the University of Vienna, Austria, and Nankai University, China, has combined advanced metabolomics with cutting-edge machine learning and a novel network modeling tool to uncover the key molecular processes underlying active aging.

30 Sep 2025

Selective impairment of translation contributes to brain aging in killifish

Aging selectively impairs the production of crucial DNA- and RNA-binding proteins, which contributes to hallmarks of aging in the brains of killifish, according to a new study.

31 Jul 2025

Evolutionary mutation weakens human immune response to solid tumors

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates.

3 Jul 2025

How nutritious is dried Gapal? Study reveals its strengths and one hidden weakness

Researchers analyzed the nutritional composition of dried Gapal, a traditional fermented milk-cereal food from Burkina Faso, revealing its high carbohydrate and mineral content. Despite its nutritional potential, high phytic acid levels may limit mineral bioavailability, especially for zinc.

7 May 2025

Can your diet slow skin aging? New review reveals what helps and what harms

Scientists reviewed recent studies and found that antioxidant-rich diets help slow skin aging, while high intake of refined sugars and trans fats accelerates it. A balanced, nutrient-dense diet may be a practical way to protect skin health and delay visible signs of aging.

6 May 2025