Quorum Sensing News and Research

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Gut microbiome atlas maps how bacteria establish themselves and shift in inflammatory bowel disease

Researchers created a microbiome-wide atlas mapping more than seven million colonization factor genes across 4,716 human gut microbial species, revealing three putative strategies linked to metabolism, stress resistance, and microbial communication. Applying the framework to inflammatory bowel disease showed that colonization-factor profiles can provide a compact, biologically interpretable view of disease-associated microbiome changes.

27 Aug 2026

Modified Clostridium sporogenes shows promise in targeting solid tumors

A research team led by the University of Waterloo is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumors from the inside out.

24 Feb 2026

External signals control oncolytic bacteria for precise cancer therapy delivery

Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune activation, and controllable therapeutic delivery. This review summarizes recent advances in the design and application of synthetic biological strategies that enhance bacterial precision, safety, and efficacy in tumor therapy.

13 Dec 2025

Targeting bacterial communication may offer antibiotic-free wound therapy

Researchers at University of California San Diego School of Medicine have discovered a previously unrecognized mechanism by which Staphylococcus aureus - one of the most common causes of skin and soft tissue infections worldwide - delays wound healing.

15 Oct 2025

UC Riverside receives $2 million grant to explore how gut bacteria shape human health

One day, bottles of probiotics might do more than keep you regular -- they could help prevent disease. To get there, a $2 million grant to UC Riverside will explore how gut bacteria shape human health.

23 Sep 2025

Natural products offer promising solutions in prosthodontics and oral implantology

Infection control is paramount in prosthodontics and oral implantology to prevent complications like denture stomatitis and peri-implantitis.

22 Aug 2025

New study maps bacterial communication to fight MRSA infections

Imagine two people talking over a walkie-talkie set. Successful communication depends on them being tuned to the same frequency.

16 Jul 2025

Synthetic Biology and the Pursuit of Living Diagnostics and Therapeutics

In this interview, Professor James J. Collins, founder of the field of Synthetic Biology, discusses his journey to founding the field of synthetic biology and the potential of living diagnostics.

From Pittcon 7 Jul 2025

Can gut microbes help prevent Alzheimer’s?

A comprehensive review explores how gut microbiota diversity and fitness influence Alzheimer’s disease (AD) risk through neuroinflammation, amyloid and tau pathology, and blood-brain barrier dysfunction. It highlights the therapeutic potential of probiotics, dietary interventions, and omics technologies in restoring microbial balance and preventing neurodegeneration.

13 Apr 2025

Bacteria engineered for remote sensing through color signatures

Bacteria can be engineered to sense a variety of molecules, such as pollutants or soil nutrients. In most cases, however, these signals can only be detected by looking at the cells under a microscope or similarly sensitive lab equipment, making them impractical for large-scale use.

11 Apr 2025

Using quorum sensing inhibitors as a novel approach to address antibiotic resistance

Pseudomonas aeruginosa is notorious for its role in food spoilage and infections, posing a significant threat to both food safety and human health.

25 Feb 2025

Gut microbes and plant foods: a powerful duo for healthy aging

Gut microbiota and phytochemicals synergize to produce bioactive metabolites that combat aging, reduce inflammation, and enhance healthspan by supporting gut and systemic health.

20 Jan 2025

Gut microbiome dynamics reveal key factors influencing Enterobacteriaceae colonization

Analysis of gut microbiomes reveals co-colonization patterns and potential therapeutic targets against Enterobacteriaceae, addressing global health challenges.

14 Jan 2025

Research shows predation drives evolution of virulence in bacteria

Opportunistic pathogens are typically benign microbes that can sometimes cause infections in individuals with weakened immune systems or when they gain access to sterile areas of the body.

22 Aug 2024

Pomegranate peel extract restores skin balance, fights infections

Pomegranate peel extract effectively restores skin microbiota balance by reducing Staphylococcus aureus and promoting Staphylococcus epidermidis growth, showcasing its potential as a non-toxic antimicrobial treatment.

5 Aug 2024

What is the ‘immune self,’ and how can this concept benefit immunological research?

A perspective review discusses the concept of the 'immune self' and how adaptive immune responses are influenced by self-similarity. The study emphasizes advances and challenges in defining self-similarity and its impact on immunological research.

13 May 2024

Wound warriors: How microbes influence healing and infection risks

Study explores how wound microbiota affect skin repair and infection risk by altering host immune responses, underscoring the complexity of microbial interactions in wound healing.

7 Apr 2024

Promising potential of probiotics and their byproducts for targeting antibiotic-resistant bacteria

The use of probiotics and antimicrobial peptides (AMPs) against multi-drug-resistant (MDR) bacteria.

27 Sep 2023

Bacteriophage cocktail can effectively disrupt Klebsiella pneumoniae biofilms on medical equipment

Researchers investigated whether a cocktail of bacteriophages coding for the depolymerase polysaccharide could effectively disrupt Klebsiella pneumoniae biofilms.

18 Sep 2023

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

Scientists have described the utility of gram-negative bacteria-derived outer membrane vesicles as vaccines and methods to expand their applications.

3 Jan 2023