Rhinosinusitis News and Research

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Rhinosinusitis is an inflammation of the paranasal sinuses and the nasal cavity lasting no longer than 4 weeks. It can range from acute viral rhinitis (the common cold) to acute bacterial rhinosinusitis. Fewer than 5 in 1,000 colds are followed by bacterial rhinosinusitis.

Study shows effectiveness of surgical treatment for chronic rhinosinusitis with nasal polyps

Both full and limited endoscopic sinus surgery significantly improve quality of life in patients with chronic rhinosinusitis with nasal polyps, according to a recent study published in Allergy.

3 Aug 2026

Airborne toxin exposure drives unique biological pattern of chronic rhinosinusitis

Researchers at the University of California San Diego and the Veterans Affairs San Diego Healthcare System have identified a distinct biological pattern of chronic rhinosinusitis (CRS), a chronic respiratory illness frequently associated with exposure to airborne toxins, such as wildfire smoke and military burn pits.

11 Feb 2026

Monthly biologic injection improves severe asthma control and reduces steroid use

A monthly injection has helped 90% of severe asthma patients reduce daily steroid tablets, which are associated with long-term side effects.

26 Nov 2025

Gut microbes may fuel allergic rhinitis symptoms

The study identifies gut microbiome alterations in allergic rhinitis, suggesting a gut-nose axis that could inform new treatment approaches for this condition.

17 Nov 2025

Veterans deployed to Iraq and Afghanistan face higher risk of chronic respiratory conditions

U.S. Veterans who served in Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF) face an increased risk of developing several chronic respiratory conditions, according to new research presented at the 2025 Annual Scientific Meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Orlando.

6 Nov 2025

Reduced endocannabinoid-related lipids found in patients with NSAID-exacerbated respiratory disease

NSAID-exacerbated respiratory disease, N-ERD, is associated with measurable changes in concentrations of lipid mediators involved in inflammation and pain modulation, a new study shows.

13 Oct 2025

Aspirin therapy does not help people suffering from chronic rhinosinusitis with nasal polyps

A randomized placebo-controlled Finnish study showed that aspirin therapy does not provide significant relief for people suffering from chronic rhinosinusitis with nasal polyps who are hypersensitive to non-steroidal anti-inflammatory drugs (NSAIDs).

8 Sep 2025

Sinus surgery proves more effective than antibiotics for chronic rhinosinusitis

Sinus surgery is more effective than antibiotics at treating chronic rhinosinusitis, according to a major clinical trial led by University College London (UCL) along with academics at the University of East Anglia and Guy's and St Thomas' NHS Foundation Trust.

28 Aug 2025

New clinical practice guideline advances surgical care for chronic rhinosinusitis

The American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) published the new Clinical Practice Guideline (CPG): Surgical Management of Chronic Rhinosinusitis today in Otolaryngology–Head and Neck Surgery.

27 May 2025

New CT-based score helps predict need for repeat sinus surgery

A new CT-scan based risk score facilitates the identification of patients at risk of revision endoscopic sinus surgery due to chronic rhinosinusitis.

3 Apr 2025

Asthma and antibiotic use increase the likelihood of revision sinus surgery

The probability of revision sinus surgery including the removal of nasal polyps is higher if the patient has asthma or is on antibiotics at the time of their initial surgery. However, higher age was not a predictor of revision surgery, according to a new study.

4 Feb 2025

Granzyme K+ CD8+ T-cells identified as key drivers of recurrent airway inflammation

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory diseases.

17 Jan 2025

How does the season of birth influence the risk of asthma and allergic rhinitis?

Finnish researchers report that season of birth likely impacts an individual’s future risk of developing airway allergy and related diseases.

20 Aug 2024

Finnish study links autumn and winter births to higher rates of asthma and allergic rhinitis

Being born in autumn or winter is associated with asthma and allergic rhinitis in Finland, a new registry-based study shows.

14 Aug 2024

Researchers identify molecular processes crucial for the maturation of Group 2 innate lymphoid cells

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Research aims to better understand the origin of eosinophils

Eosinophils are specialized cells of our immune system. They are identified by their distinctive granules that stain red when treated with an acidic reagent, eosin, which gave them their name.

22 May 2024

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

IU surgeon-scientist investigates the role of sinus microbiome in chronic rhinosinusitis

An Indiana University School of Medicine surgeon-scientist is leading a multi-institutional grant investigating the role of the sinus microbiome in chronic rhinosinusitis, an inflammatory disease that causes the lining of the sinuses to swell.

1 Feb 2024

Japanese study uncovers protective role of nasal microbiome in eosinophilic chronic rhinosinusitis

Like other countries in the world, Japan has witnessed a worrisome increase in the prevalence of chronic rhinosinusitis (CRS) over the last decade.

6 Nov 2023

Olfactory dysfunction following mild SARS-CoV-2 infection associated with neurological changes in structural connectivity

Researchers investigated the changes in olfactory bulb volume and structural connectivity of the brain in patients with olfactory dysfunction following mild SARS-CoV-2.

14 Aug 2023