Rifampicin News and Research

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Can ibuprofen improve drug-resistant tuberculosis treatment?

While ibuprofen reduced inflammatory markers in drug-resistant TB patients, it did not enhance treatment outcomes, indicating the need for further research.

3 Jul 2026

New pico-calorimeter detects antibiotic resistance via direct heat traces

When living cells grow, divide, or respond to drugs, they give off tiny amounts of heat that offer information about what the cells are doing. But since these heat signals are so vanishingly small, they have been traditionally impossible to measure directly.

17 Jun 2026

Novel therapeutic agent proposed to combat drug resistant tuberculosis

A research team led by Associate Professor Noriyuki Kurita from the Department of Computer Science and Engineering at Toyohashi University of Technology and by Associate Professor Pornpan Pungpo from Ubon Ratchathani University in Thailand has proposed a novel therapeutic agent for tuberculosis, using high-precision molecular simulation techniques.

29 May 2026

WHO urges faster TB detection with new point-of-care tests

On World TB Day, the World Health Organization (WHO) is urging countries to accelerate action to end tuberculosis (TB) and expand access to lifesaving services by using new innovations such as diagnostic tests that can be used near the point-of-care and tongue swabs that can help detect the disease faster reaching more people.

24 Mar 2026

Researchers identify mechanism explaining chemical disruption of sex hormones

Researchers at the University of Oulu have identified a previously unknown mechanism in humans that may explain why certain medicines and environmental chemicals disrupt the balance of sex hormones.

11 Mar 2026

New method isolates true transcription factor targets in tuberculosis bacteria

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.

2 Mar 2026

Frozen in time: Ancient bacteria reveal evolution of drug resistance

Bacteria have evolved to adapt to all of Earth's most extreme conditions, from scorching heat to temperatures well below zero.

17 Feb 2026

WHO and Novartis extend partnership to eliminate leprosy for another 5 years

Access to treatment for leprosy is essential to global efforts to eliminate leprosy, says the World Health Organization (WHO) ahead of World Leprosy Day, to be observed on 25 January.

22 Jan 2026

High-dose rifampicin does not improve survival in tuberculosis meningitis

Each year, 11 million people worldwide develop tuberculosis, and about 1.4 million die from it. Meningitis occurs in 1–2% of patients and is the most severe complication of tuberculosis, arising when the bacteria reach the brain.

17 Dec 2025

endTB-Q trial highlights importance of individualized regimens

Some patients with highly drug-resistant tuberculosis could benefit from a shorter treatment with fewer drugs while others may warrant more aggressive therapy, according to the findings of a new study led by an international group of researchers including scientists from Harvard Medical School and conducted across six countries in Asia, Africa, and South America.

17 Jul 2025

New study moves closer to defeating dormant tuberculosis cells

New drugs that target 'zombie' tuberculosis (TB) cells are now a step closer, thanks to a new study led by the University of Surrey, published in Scientific Reports.

4 Jul 2025

Diabetes fuels antibiotic resistance, worsening infections and treatment challenges

A new study reveals that diabetes significantly accelerates the emergence and spread of antibiotic-resistant Staphylococcus aureus infections, highlighting a major public health concern.

17 Feb 2025

Multidrug-resistant TB in children is rising: Urgent global action needed

Researchers analyzed global trends in multidrug-resistant tuberculosis (MDR-TB) among children and adolescents, revealing rising incidence rates, gender disparities, and the disproportionate impact on low-income regions.

12 Feb 2025

Diabetes plays key role in the emergence and expansion of antibiotic resistance

Antibiotics are powerful, fast-acting medications designed to eradicate bacterial infections. However, in recent years, their dependability has waned as antibiotic resistant bacteria continues to evolve and spread.

12 Feb 2025

Unraveling the mystery of drug-induced liver injury

DILI is broadly categorized into intrinsic and idiosyncratic types. Intrinsic hepatotoxins, such as APAP, cause dose-dependent injury, while idiosyncratic DILI involves complex immune and metabolic interactions that remain poorly understood.

13 Dec 2024

WHO grants prequalification to molecular diagnostic test for tuberculosis

The World Health Organization (WHO) has granted prequalification to the molecular diagnostic test for tuberculosis (TB) called Xpert® MTB/RIF Ultra.

5 Dec 2024

Quabodepistat combo shows promise for safer, faster tuberculosis treatment

Study highlights the safety and early bactericidal activity of quabodepistat when combined with delamanid, bedaquiline, or both, offering potential for shorter and more tolerable tuberculosis treatment regimens.

1 Dec 2024

WHO reports alarming rise in tuberculosis cases in 2023

The World Health Organization (WHO) today published a new report on tuberculosis revealing that approximately 8.2 million people were newly diagnosed with TB in 2023 – the highest number recorded since WHO began global TB monitoring in 1995.

29 Oct 2024

Advanced 3D model replicates hair follicle environment to better evaluate drug treatments

Hair follicles are complex structures that surround the hair root, anchoring it to the skin and giving the hair its hold.

29 Jul 2024

WHO updates Bacterial Priority Pathogens List to combat antimicrobial resistance

The World Health Organization (WHO) today released its updated Bacterial Priority Pathogens List (BPPL) 2024, featuring 15 families of antibiotic-resistant bacteria grouped into critical, high and medium categories for prioritization.

20 May 2024