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New platform enables large-scale production of custom proteins

Scientists have been hard at work for more than 20 years to instruct biological systems, such as E. coli cells, to produce proteins they don't naturally do.

27 Aug 2026

D-serine promotes gastric cancer growth by suppressing tumor immunity

Researchers from Keio University have found that D-serine increases the growth of gastric cancer by creating an immunosuppressive and anti-inflammatory tumor microenvironment.

6 Aug 2026

Study reveals evolutionary shift in gene crucial for the human nervous system

Certain variants in the PSPH gene, which encodes an enzyme called phosphoserine phosphatase, prevent the body from making sufficient amounts of amino acid L-serine, leading to a range of nervous system problems.

5 Aug 2026

New blood test improves colorectal cancer recurrence risk prediction

A single preoperative blood sample may help improve the prediction of recurrence or metastasis in patients with colorectal cancer.

21 Jul 2026

New breast cancer classification system predicts immunotherapy response success

The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant portion of breast cancer patients fail to respond to these therapies.

3 Jul 2026

Blocking nerve signaling may reduce cancer-associated cachexia

Researchers have uncovered a previously unrecognized pathway linking lung tumor genetics, diet, and the nervous system that drives cancer-associated cachexia, according to a new study in mice.

2 Jul 2026

Genetic testing finds breast cancer risks that standard screening models miss

Population-based pathogenic variant testing identified breast cancer susceptibility gene carriers who would often be missed by clinical risk models, even when polygenic risk scores were added. In the WISDOM Study analysis, fewer than 1% of high-penetrance variant carriers would have received the same high-risk screening recommendation using clinical plus polygenic risk alone.

1 Jun 2026

Pim1 identified as promising therapeutic target for inflammatory arthritis treatment

The research team led by Professor Zhongyu Xie from Sun Yat-sen University revealed a new mechanism by which Pim1 regulated Th17 cell differentiation through mitochondrial metabolism.

22 May 2026

Cancer-driving MYC protein also helps tumors repair damaged DNA

A protein best known for driving cancer growth also helps damaged tumor cells survive by repairing their DNA, according to a new study that could influence how some cancers are treated.

17 May 2026

Organic lithium salts may affect many cellular level changes in Alzheimer's disease

Lithium chloride may affect many cellular level changes in Alzheimer's disease, a new study from the University of Eastern Finland (UEF) shows.

6 May 2026

Obesity may leave immune cells stuck in inflammatory mode after weight loss

A new EMBO Reports study suggests that obesity can leave a lasting epigenetic imprint on CD4 T cells, delaying the restoration of adaptive immune balance after weight loss. Using mouse models and human cohorts, researchers linked this immune “memory” to DNA methylation changes, saturated fatty acids, autophagy, and immune senescence.

28 Apr 2026

SARS-CoV-2 rarely reaches first-trimester placentas but still disrupts early pregnancy immunity

Researchers analyzing 761 first-trimester pregnancies found that SARS-CoV-2 was rarely detected in placental tissues, suggesting in utero transmission early in pregnancy is uncommon. However, maternal infection was linked to immune dysregulation at the maternal-fetal interface, altered trophoblast signaling, and inflammatory changes that could affect placental development.

14 Apr 2026

AI-powered chemistry accelerates discovery of selective cancer inhibitors

Recently, the Insilico team's research entitled "An Internal Sulfur-Lone Pair Interaction Enabled the Discovery of Potential and Sub-Family Selective PKMYT1 Inhibitors" was invited for publication as a cover Feature in ChemMedChem.

9 Apr 2026

Stard7 plays unexpected role in intestinal cancer development

A new study led by researchers at the University of Liège highlights the unexpected role of Stard7 in the development of intestinal cancers.

2 Apr 2026

How could bisphenol A raise depression risk? Study identifies six key molecular targets

An integrative Translational Psychiatry study linked BPA exposure to major depressive disorder by identifying 571 shared targets and six core genes, with genetic, transcriptomic, docking, and mouse-model data supporting plausible mechanistic pathways. The strongest signals pointed to AKT1, SRC, PLCG2, and JAK3 as potential contributors, while EGFR appeared protective.

31 Mar 2026

Mediterranean diet may protect health through mitochondrial microproteins

A new study led by researchers at the USC Leonard Davis School of Gerontology suggests that the benefits of the Mediterranean diet may be driven, in part, by tiny proteins hidden within our mitochondria, opening a new window into how diet shapes aging and disease risk.

23 Mar 2026