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Tau proteins are microtubule-associated proteins found in neurons in the brain.

Study explains why Amazonian Indigenous populations show low dementia prevalence

In two Indigenous communities living pre-industrial lifestyles in the Bolivian Amazon, dementia is remarkably uncommon.

15 Sep 2026

Scientists traced a hidden immune route that may worsen tau-linked brain damage

In a mouse model of tauopathy, conventional type 1 dendritic cells (cDC1s) cross-presented brain-derived antigens in deep cervical lymph nodes, priming CD8+ T cells that accumulated in the brain and promoted neurodegeneration. Disrupting cDC1s or their cross-presentation activity reduced CD8+ T-cell infiltration and protected against neuronal loss, while human primary tauopathy samples also showed increased brain CD8+ T cells, although cDC1 involvement in humans remains unconfirmed.

6 Sep 2026

Brain-protecting immune cells may actually drive Alzheimer's disease

Immune cells that normally protect the body from damage by attacking foreign or infected cells are found in the brains of patients with Alzheimer's disease and related disorders at much higher levels than in healthy brains.

3 Sep 2026

Shared protein pathology redefines treatment for multiple neurodegenerative diseases

On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem like unrelated diseases.

24 Aug 2026

FDA clears innovative blood test for earlier Alzheimer's diagnosis

The U.S. Food and Drug Administration (FDA) has cleared for marketing an innovative blood test with underlying technology invented at Washington University School of Medicine in St. Louis for the early diagnosis of Alzheimer's disease.

21 Aug 2026

Sino Biological launches precisely characterized full-length p-Tau217 protein to advance next-generation Alzheimer’s Biomarker assay development

Sino Biological Inc. is pleased to announce the launch of its Recombinant Human p-Tau217 Protein (Cat. No. T08-50SN), a full-length, tag-free Tau reagent developed to support Alzheimer’s disease biomarker assay development, antibody evaluation, and Tau biology research.

From Sino Biological Inc. 4 Aug 2026

Blood tests improve Alzheimer's detection in Down syndrome patients

New blood tests that detect early changes associated with Alzheimer's disease are making diagnosis easier and accessible to more patients, since they are less invasive than the brain scans or spinal taps typically used for a definitive diagnosis.

27 Jul 2026

Tau buildup in progressive supranuclear palsy alters brain networks linked to thinking and behavior

Researchers at Japan's National Institutes for Quantum Science and Technology (QST) have found that tau buildup in progressive supranuclear palsy (PSP) may affect brain networks involved in thinking and behavior.

17 Jul 2026

SORLA protein may protect the brain from toxic tau tangles

Alzheimer's disease and many other forms of neurodegeneration share a common culprit. In these diseases, tau proteins that normally stabilize neuronal microtubule filaments within our nervous system networks instead form noxious knots and gradually disrupt the circuits they would otherwise preserve.

17 Jul 2026

Sleeping longer may signal early Alzheimer's-related brain changes

Regularly sleeping long hours each night is associated with higher levels of an Alzheimer's-related protein in the blood, even accounting for other health factors, suggests a new study from UT Health San Antonio, the academic health center of The University of Texas at San Antonio.

15 Jul 2026

Weill Cornell Medicine receives federal grant to study new gene therapy for Alzheimer's disease

The National Institute on Aging of the National Institutes of Health has awarded a five-year grant initially worth $8.37 million for Weill Cornell Medicine researchers to study a new gene therapy for Alzheimer's disease in people who have a high genetic risk of developing the condition.

8 Jul 2026

Study provides new insights into biological processes linked to Huntington’s disease

A study conducted by the Sant Pau Research Institute (IR Sant Pau) and Hospital de Sant Pau has identified for the first time in living individuals a brain pattern related to the tau protein that changes according to the stage of Huntington's disease.

6 Jul 2026

Scientists discover how Arc protein spreads Alzheimer's brain pathology

Alzheimer's disease is driven by a buildup of a toxic protein called Tau that kills neurons. As toxic Tau spreads to new regions of the brain, symptoms become worse and ultimately fatal.

29 Jun 2026

Glucosamine may worsen Alzheimer’s by fueling abnormal brain glycosylation

A Nature Metabolism study identifies brain hyperglycosylation as a metabolic driver of Alzheimer’s disease, with increased N-glycan biosynthesis seen in human AD tissue and mouse models. Reducing glycosylation improved memory in AD mice, while glucosamine worsened memory deficits in 5xFAD mice and was associated with poorer outcomes in dementia patients.

14 Jun 2026

Senior Care Authority kicks off Alzheimer's and Brain Awareness Month with six science-backed habits that may help reduce dementia risk

An estimated 7.4 million Americans aged 65 and older are now living with Alzheimer's disease, according to the Alzheimer's Association's 2026 Alzheimer's Disease Facts and Figures report, and that number is projected to climb to nearly 13 million by 2050.

5 Jun 2026

Advanced tau imaging improves early Alzheimer’s disease detection accuracy

A new brain imaging test can detect a key hallmark of Alzheimer's disease before symptoms appear and earlier than the method currently used in clinical practice in the United States and Europe, report University of Pittsburgh School of Medicine researchers today in The Lancet.

28 May 2026

Poor sleep may flag early Alzheimer’s risk in genetically vulnerable older women

Poorer subjective sleep quality was linked to worse visual memory and greater limbic tau burden in older women with higher genetic risk for Alzheimer’s disease. The findings suggest sleep complaints may help identify women at elevated risk for early AD-related brain and cognitive changes, but larger longitudinal studies are needed.

20 May 2026