Transcatheter Aortic Valve Replacement News and Research

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Transfemoral J-Valve device improves symptoms in severe aortic regurgitation patients

New research simultaneously published today in JSCAI and presented at New York Valves 2026 reported favorable one-year outcomes in patients with symptomatic severe aortic regurgitation following treatment with the investigational J-Valve Transfemoral System.

25 Jun 2026

Google search trends reflect a shift toward minimally invasive heart care

New research found that public interest in Transcatheter Aortic Valve Replacement (TAVR) increased substantially over the last decade, with Google search volume rising by 340% from 2015 to 2025, while searches for SAVR (Surgical Aortic Valve Replacement) declined by 42%.

23 Apr 2026

Tirzepatide significantly reduces cardiovascular risk in high-risk patients

Two new studies show that tirzepatide, a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist (RA), significantly reduces cardiovascular risk in high-risk patients, including those undergoing percutaneous coronary intervention (PCI) and those with obesity undergoing transcatheter aortic valve replacement (TAVR).

23 Apr 2026

Deferring PCI before TAVR shows comparable outcomes in elderly patients

Older patients with coronary artery disease scheduled for transcatheter aortic valve replacement (TAVR) had comparable outcomes regardless of whether they underwent percutaneous coronary intervention (PCI) before TAVR, according to findings from the PRO-TAVI study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

29 Mar 2026

Early TAVR shows greatest stroke reduction in patients aged 65 to 70

New analysis from the EARLY TAVR trial showed patients between the age of 65 and 70 years old derived the most benefits of a strategy of early intervention with transcatheter aortic valve replacement (TAVR) compared to other age groups, especially in regards to stroke risk, and in regards to the composite of death, stroke, and heart failure hospitalization.

2 May 2025

Single antiplatelet therapy after TAVR linked to lower mortality and bleeding

Findings from the Transfusion Requirements in Transcatheter Aortic Valve Implantation (TRITAVI) registry demonstrate that single antiplatelet therapy (SAPT) after transcatheter aortic valve replacement (TAVR) is associated with a significantly lower incidence of six-month mortality and major bleeding risk compared to dual antiplatelet therapy (DAPT).

2 May 2025

Trilogy valve demonstrates safety and effectiveness in treating aortic regurgitation

Patients who underwent transcatheter aortic valve replacement (TAVR) with a valve designed to treat aortic regurgitation had an overall mortality rate of just 8.1% at one year, well below the trial's prespecified goal of 25% to show non-inferiority, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

31 Mar 2025

Embolic protection device does not reduce stroke rate in TAVR procedure

A device designed to remove embolic material—fragments of tissue that can be released into the bloodstream during transcatheter aortic valve replacement (TAVR)—did not result in a reduction in the rate of stroke, according to a randomized trial presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Heart failure patients benefit from dapagliflozin after TAVR procedure

Patients with heart failure who took dapagliflozin, a sodium-glucose co-transporter-2 (SGLT-2) inhibitor, after undergoing transcatheter aortic valve replacement (TAVR) were significantly less likely to die or experience worsening heart failure at one year compared with patients who did not take the drug, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Mechanical aortic valves showed improved long-term survival in patients aged 60 and younger

A late-breaking study presented today at the 2025 Society of Thoracic Surgeons (STS) Annual Meeting reveals that mechanical aortic valve replacements (AVRs) provide significant long-term survival benefits for patients aged 60 and younger compared to bioprosthetic valves. The study, leveraging data from the STS Adult Cardiac Surgery Database (ACSD), offers the most comprehensive analysis to date of prosthetic valve outcomes, encompassing over 100,000 patients.

26 Jan 2025

Cardiac damage framework may identify patients who could benefit from earlier TAVR

Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).

29 Oct 2024

Early intervention with TAVR proves safe and effective for asymptomatic aortic stenosis

The first powered randomized trial examining early intervention with transcatheter aortic valve replacement (TAVR) in patients with asymptomatic, severe aortic stenosis (AS) found this strategy to be both a safe and effective alternative to clinical surveillance (CS).

29 Oct 2024

TCT 2024 to feature latest advances in interventional cardiovascular medicine

The Cardiovascular Research Foundation is pleased to announce the late-breaking clinical trials and science to be featured at TCT 2024.

28 Aug 2024

Medical device may aid stroke survivors during heart valve replacement procedure

Recently published research shows a medical device may be beneficial for patients who have previously had a stroke and are planning to undergo a transcatheter aortic valve replacement, a type of heart valve operation.

31 Jul 2024

Medtronic’s Evolut valve reduces dysfunction, improves quality of life in women with severe aortic stenos

Medtronic, the global leader in healthcare technology, today announced new data from the largest head-to-head comparative trial of transfemoral transcatheter aortic valve replacement (TAVR), the SMall Annuli Randomized To Evolut or SAPIEN (SMART) Trial, looking exclusively at women.

20 May 2024

Study shows comparable outcomes for TAVR and SAVR in aortic valve replacement

A new study demonstrated parity between a minimally invasive procedure to replace the aortic valve in the heart - transcatheter aortic valve replacement (TAVR) - and surgical aortic valve replacement (SAVR).

15 May 2024

New data reveals optimal timing for percutaneous coronary intervention in TAVR patients

New data reveals that percutaneous coronary intervention (PCI) can be safely performed before, during, or after transcatheter aortic valve replacement (TAVR) for patients with stable coronary artery disease (CAD).

3 May 2024

SMART study shows hemodynamic benefits of self-expanding valves in aortic stenosis patients

Additional analysis from the SMall Annuli Randomized To Evolut or SAPIEN (SMART) study demonstrated clinical non-inferiority of self-expanding valves (SEV) versus balloon-expandable valves (BEV) in aortic stenosis patients undergoing transcatheter aortic valve replacement (TAVR) and confirmed valve performance superiority over time based on hemodynamics.

3 May 2024

New transcatheter heart valve shows promise in treating aortic stenosis

Recent findings from a study on a transcatheter heart valve (THV) system, which includes a new class of transcatheter aortic valve, showed positive results in the device's ability to function as a healthy and natural aortic valve in patients with aortic stenosis (AS).

3 May 2024

STS introduces new risk calculators for valve surgeries

The expanding use of transcatheter technologies has changed the landscape in the treatment of valvular disease in adult cardiac patients, with valve surgery rapidly shifting to more complex interventions frequently involving other concomitant procedures.

26 Apr 2024

Transcatheter Aortic Valve Replacement News and Research

Transfemoral J-Valve device improves symptoms in severe aortic regurgitation patients

Google search trends reflect a shift toward minimally invasive heart care

Tirzepatide significantly reduces cardiovascular risk in high-risk patients

Deferring PCI before TAVR shows comparable outcomes in elderly patients

Early TAVR shows greatest stroke reduction in patients aged 65 to 70

Single antiplatelet therapy after TAVR linked to lower mortality and bleeding

Trilogy valve demonstrates safety and effectiveness in treating aortic regurgitation

Embolic protection device does not reduce stroke rate in TAVR procedure

Heart failure patients benefit from dapagliflozin after TAVR procedure

Mechanical aortic valves showed improved long-term survival in patients aged 60 and younger

Cardiac damage framework may identify patients who could benefit from earlier TAVR

Early intervention with TAVR proves safe and effective for asymptomatic aortic stenosis

TCT 2024 to feature latest advances in interventional cardiovascular medicine

Medical device may aid stroke survivors during heart valve replacement procedure

Medtronic’s Evolut valve reduces dysfunction, improves quality of life in women with severe aortic stenos

Study shows comparable outcomes for TAVR and SAVR in aortic valve replacement

New data reveals optimal timing for percutaneous coronary intervention in TAVR patients

SMART study shows hemodynamic benefits of self-expanding valves in aortic stenosis patients

New transcatheter heart valve shows promise in treating aortic stenosis

STS introduces new risk calculators for valve surgeries

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