Allergy News and Research

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The term allergy encompasses a wide range of conditions; it is not a disease in itself. In 1906 Clemens von Pirquet was the first to describe allergies as a changed or altered reaction of the immune system in response to exposure to foreign proteins. These days the term allergy – medically termed hypersensitivity, signifies an exaggerated reaction to foreign substances.

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells.

18 Aug 2023

Severe COVID-19 causes long-lasting changes to immune system stem cells

Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body's immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators.

18 Aug 2023

Immune cells present in people months before influenza infection, finds study

St. Jude Children's Research Hospital scientists, in collaboration with the Institute of Environmental Science and Research (ESR) Limited, found that immune cells present in people months before influenza (flu) infection could more accurately predict if an individual would develop symptoms than current methods which primarily rely on antibody levels.

18 Aug 2023

New findings could develop effective vaccines or treatments for chikungunya fever

Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell-;perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, can manage to escape antibodies circulating in the bloodstream.

18 Aug 2023

Interactomics-based analysis suggests that rhinitis and rhinitis with asthma are mechanistically different diseases

Researchers used human transcriptomic data to differentiate the molecular mechanisms associated with two phenotypes of allergic rhinitis: rhinitis and rhinitis with asthma.

17 Aug 2023

Pig kidney xenotransplantation continues to function well after 32 days

Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support.

16 Aug 2023

COVID-19 mRNA vaccine or booster during pregnancy benefits mother and baby, study finds

Receiving a COVID-19 mRNA vaccine or booster during pregnancy can benefit pregnant people and their newborn infants, according to findings recently published in Vaccine.

11 Aug 2023

Children raised in rural areas have better regulated immune systems

Children raised in rural environments who spend a lot of time outdoors with some exposure to animals grow to have better regulated immune systems than children living in urban environments, a new study has found.

3 Aug 2023

NIH awards $18 million to develop novel chikungunya vaccine

The Access to Advanced Health Institute (AAHI) announced today that it has received an $18 million award from the National Institutes of Health (NIH) to develop a temperature stable, single-dose vaccine candidate for the chikungunya virus.

3 Aug 2023

Child-friendly HIV drug could improve treatment outcomes

Researchers at the University of Colorado Anschutz Medical Campus have helped confirm the dosing, safety and effectiveness of a drug formulation designed for treating children with human immunodeficiency virus (HIV).

2 Aug 2023

The evolving emergence of alpha-gal syndrome in the United States

Researchers investigated alpha-gal syndrome (AGS) prevalence and geographic distribution.

2 Aug 2023

New COVID-19 vaccine from HIPRA Human Health approved by MHRA

Bimervax, the COVID-19 vaccine developed by HIPRA Human Health, has today been authorized by the Medicines and Healthcare products Regulatory Agency (MHRA).

1 Aug 2023

Study illuminates new connections between diet and immunity

A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and disease, reports an early stage study by Van Andel Institute scientists and collaborators.

28 Jul 2023

Expert warns of the increasing risks of European holidays

As the UKHSA issues new essential health guidance for travellers going abroad, a leading testing expert warns of the increasing risks of European holidays.

28 Jul 2023

Human-swine influenza A transmission and evolution of variants

A new study of the strain of influenza A responsible for the 2009 H1N1 pandemic-;pdm09-;shows that the virus has passed from humans to swine about 370 times since 2009, and subsequent circulation in swine has resulted in the evolution of pdm09 variants that then jumped from swine to humans.

27 Jul 2023

Study: 82% of child deaths in low-income countries could be prevented

Eighty-two percent of child deaths in low-income countries could be prevented, according to a study from the international CHAMPS network published in JAMA Network Open.

26 Jul 2023

NIAID awards $13.7 million grant to investigate multidrug resistant organisms in nursing homes

The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a $13.7 million, five-year grant to a team of researchers to investigate multidrug resistant organisms (MDROs) in nursing homes throughout the United States.

25 Jul 2023

Early life food allergy associated with increased risk of asthma and reduced lung growth

Having a food allergy as a baby is linked to asthma and reduced lung function later in childhood, according to a world first study.

25 Jul 2023

Describing patterns of pediatric allergies across the United States using EHR

In the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic health record (EHR) data from more than 200,000 pediatric patients to describe patterns of pediatric allergies across the United States, validating a population-level pattern of allergy development known as the "allergic march," in which allergies first present as eczema, followed by food allergies, asthma, and environmental allergies.

25 Jul 2023

Donating a kidney can be safe for people living with HIV, study shows

Based on findings from a study published today in the journal The Lancet Regional Health - Americas, researchers at Johns Hopkins Medicine and three collaborating medical institutions suggest that people living with the human immunodeficiency virus (HIV) who donate a kidney to other people living with HIV (PLWH) have a low risk of developing end-stage kidney disease (ESKD) or other kidney problems in the years following the donation.

24 Jul 2023