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A slight increase in Mpox cases across the globe, along with an increase in deaths

The WHO discusses genomic sequencing of the Mpox virus, in addition to providing public and clinical health links between HIV and Mpox.

24 Jan 2023

WHO’s 14th situation report for the multi-country outbreak of mpox overviews the clinical and public health links between HIV and mpox

In the present report, researchers reported the most recent findings of MPXV infections.

23 Jan 2023

Mpox has been silently circulating in non-mpox-endemic nations for 20 years, according to new study

Researchers described the evolution of the mpox virus (MPXV) before the 2022 outbreak.

19 Jan 2023

Research explores the utility of epigenetically predicted BMI

DNA methylation is an accurate predictor of current BMI and a poor predictor of future BMI.

18 Jan 2023

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers investigated the ability of kinetin (N6-furfurylaminopurine, MB-905) to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proliferation in vitro.

17 Jan 2023

The main source of editing of the mpox virus genome during the 2022 outbreak

Researchers investigated the main source of editing of the 2022 mpox virus genome.

11 Jan 2023

COVID-19 vaccine potency and breadth improved by nanoparticle-conjugated adjuvants

In a recent study posted to bioRxiv*, researchers designed a nanoparticle (NP)-conjugated toll-like receptor 9 (TLR9) agonist to improve the adjuvanticity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.

8 Jan 2023

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine.

28 Dec 2022

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A patient with relapsed T cell leukemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

12 Dec 2022

Colorectal cancer doesn’t wait - DNA methylation tests facilitate earlier treatment

In this interview, Yantao Li and Zhe Wang, Director of Cancer Early Screening Products and the Product Director of Oncology at BGI Genomics, talks to NewsMedical about colorectal cancer (CRC), including why incidences are important and the importance of screening.

From BGI Genomics 6 Dec 2022

NUS scientists develop novel low-cost method of testing for cancers

Scientists from the National University of have discovered a novel low-cost method of testing for cancers.

5 Dec 2022

Research finds higher rate of rare tandem repeats in the genomes of individuals with schizophrenia

In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides – the basic structural unit of DNA coded in the base of chemicals cytosine (C), adenine (A), guanine (G) and thymine (T) – is repeated multiple times in tandem. An example might be: CAG CAG CAG, in which the pattern CAG is repeated three times.

30 Nov 2022

Exploring synthetic engineering of bacteriophages

In a new study, researchers demonstrated biological bacteriophage containment and synthetic engineering.

24 Nov 2022

Study shows clear shifts in SARS-CoV-2 mutational spectrum during evolution

Researchers examined whether the mutational process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) itself has changed during the evolution of SARS-CoV-2.

23 Nov 2022

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

In a recent study published in the journal npj Vaccines, researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer.

15 Nov 2022

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Researchers used whole genome sequencing to evaluate monkeypox virus samples from Washington and Ohio states in the United States and identified 25 samples with open reading frame (ORF)-disrupting mutations.

7 Nov 2022

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Researchers examined the role of epigenetic modifications of the host cell gene expression in determining the pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and explored the use of vitamin D as a therapeutic agent against coronavirus disease 2019 (COVID-19).

19 Oct 2022

Scientists discover a promising strategy for development of broad-spectrum antiviral therapies

Researchers have identified a promising strategy for development of broad-spectrum antiviral therapies that centers around promoting a strong immune response capable of stopping a number of viruses in their infectious tracks.

10 Oct 2022