Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Automata raises US $50 million in series B financing to accelerate automation in life science

Automata raises US $50 million in series B financing to accelerate automation in life science

Certain flavonoids inhibit an enzyme involved in the formation of key hormone in yellow fever mosquito

Certain flavonoids inhibit an enzyme involved in the formation of key hormone in yellow fever mosquito

Ensitrelvir, a novel SARS-CoV-2 antiviral

Ensitrelvir, a novel SARS-CoV-2 antiviral

Researchers overcome key challenge in creating sulfur-based medicines

Researchers overcome key challenge in creating sulfur-based medicines

What does the Future of Artificial Intelligence Look Like within the Life Sciences?

What does the Future of Artificial Intelligence Look Like within the Life Sciences?

Novel molecule shows ability to inhibit the replication of all coronaviruses

Novel molecule shows ability to inhibit the replication of all coronaviruses

New analysis highlights growing trends in combination cancer therapy clinical trials

New analysis highlights growing trends in combination cancer therapy clinical trials

Screening assays identify TMPRSS2 inhibitors from drug repurposing candidates useful as COVID-19 therapeutic

Screening assays identify TMPRSS2 inhibitors from drug repurposing candidates useful as COVID-19 therapeutic

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

Study examines whether viagra-like drug may be effective in treating vascular dementia

Study examines whether viagra-like drug may be effective in treating vascular dementia

Research reveals why Black women experience higher breast cancer mortality

Research reveals why Black women experience higher breast cancer mortality

Researchers identify a bivalent histone-mark switch essential for angiogenesis

Researchers identify a bivalent histone-mark switch essential for angiogenesis

Using interdisciplinary approach to beat cancer

Using interdisciplinary approach to beat cancer

Study provides atomistic level insight into target residence time of small molecule kinase inhibitors

Study provides atomistic level insight into target residence time of small molecule kinase inhibitors

New study offers valuable information on ocular drug metabolism and pharmacokinetics

New study offers valuable information on ocular drug metabolism and pharmacokinetics

Blood proteoforms may help predict liver transplant rejection

Blood proteoforms may help predict liver transplant rejection

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Study opens the door to a new approach to attacking herpesviruses

Study opens the door to a new approach to attacking herpesviruses

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C