Estradiol News and Research

RSS

Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.

Menopausal changes may drive a heightened appetite for fatty foods and weight gain

A new study in mice suggests that declining estrogen levels lower the taste buds' sensitivity to fats, which may drive a heightened appetite for fatty foods-;and weight gain-;after menopause.

4 Mar 2021

Endocrine-targeted therapies can prevent and treat endometrial cancer recurrence

In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer.

24 Feb 2021

Xenograft model for invasive lobular carcinoma simulates tumor with high accuracy

Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast.

22 Feb 2021

Cissampelos pareira L. extracts demonstrate anti-SARS-CoV-2 activity in vitro

A team of scientists from India has recently investigated the antiviral potency of a traditional medicinal plant Cissampelos pareira L. in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The findings reveal that both whole-plant extracts and bioactive compounds can inhibit SARS-CoV-2 replication by modulating estrogen receptor 1 (ESR1) activity.

21 Feb 2021

Molecular imaging can predict response to novel metastatic breast cancer treatment

Molecular imaging can successfully predict response to a novel treatment for ER-positive, HER2-negative metastatic breast cancer patients who are resistant to hormonal therapy.

17 Feb 2021

Study shows that human hormones also follow a seasonal pattern

Our minds may be affected by winter's long nights or spring's flowers, but what about our bodies? A new study at the Weizmann Institute of Science reveals that our hormones also follow a seasonal pattern.

4 Feb 2021

Experts advise disaggregating data on COVID-19 patients by sex

Researchers at Yale University School of Medicine have highlighted the importance of ensuring studies of patients with coronavirus disease 2019 (COVID-19) report data in a sex-disaggregated manner.

24 Jan 2021

Female reproductive hormones may be protective against COVID-19

In an article recently published in Trends in Endocrinology & Metabolism, Graziano Pinna from the University of Illinois in Chicago outlines some of the evidence suggesting that female reproductive hormones may play a role in the sex bias that has been observed in coronavirus disease 2019 (COVID-19).

29 Nov 2020

Sex steroids may play a protective role in COVID-19, shows study

A new paper from a UIC researcher shows evidence that suggests sex steroids may play a role in protecting against COVID-19 symptoms.

24 Nov 2020

Mass production of SARS-CoV-2 ORF8 protein using a chemical-inducible system in tobacco BY-2 cells

Researchers from the Japan Advanced Institute of Science and Technology (JAIST) and Ishikawa Prefectural University, Japan, recently attempted to synthesize the ORF8 protein with the help of a chemical-inducible protein production system using tobacco BY-2 cells. This study has been published demonstrated in the preprint server, bioRxiv.

9 Oct 2020

Study may explain why hormone therapy slows progression of heart disease

As one of the most common treatments for effectively managing menopause symptoms, hormone therapy (HT) is also known to provide multiple health benefits, including slowing the progression of atherosclerosis.

28 Sep 2020

NAMS publishes the 2020 Genitourinary Syndrome Of Menopause Position Statement

The North American Menopause Society announces publication of its 2020 Genitourinary Syndrome of Menopause Position Statement.

1 Sep 2020

Study suggests role for estrogen replacement to protect women against Alzheimer's

Biological sex influences the effect of amyloid beta on alterations to tau protein characteristic to Alzheimer's disease, suggesting a role for estradiol in preventing the disease in women, report scientists in the Journal of Alzheimer's Disease

1 Sep 2020

Estradiol appears to help in female SARS-CoV-2 infection

A new study published on the preprint server medRxiv in August 2020 shows that the risk of infection is high for pre-menopausal women but the risk of death is much higher for men in the same age group and throws light on the protective nature of estradiol therapy in post-menopausal women.

26 Aug 2020

A wearable sensor printed on natural polymer for monitoring body fluids present in sweat

A wearable sensor printed on microbial nanocellulose, a natural polymer, has been created in Brazil by researchers at the University of São Paulo in São Carlos in collaboration with colleagues at São Paulo State University in Araraquara, the University of Araraquara, the University of Campinas, and the Brazilian National Nanotechnology Laboratory.

17 Aug 2020

TGen review: Postmenopausal women at higher risk for developing NALFD

A review article authored by a researcher at the Translational Genomics Research Institute, an affiliate of City of Hope, suggests that following menopause, women are at higher risk for developing nonalcoholic fatty liver disease, a chronic condition caused by the build-up of excess fat in the liver not caused by alcohol.

14 Aug 2020

$New studies identify contributors to higher risk of stress fractures in female runners$

New studies identify contributors to higher risk of stress fractures in female runners

Running is one of the most popular forms of exercise, enjoyed by a broad range of age groups and skill levels. More women are running recreationally compared to men; specifically 54% of runners are female as indicated by a 2018 National Runner Survey.

11 Aug 2020

Estrogen modestly protective against COVID-19?

Almost from the beginning, scientists have been struck by the disproportionately higher numbers of men and older adults who have developed severe COVID-19 disease compared to younger individuals and women. Prior research has shown that in 37 of the 38 countries from which sex-stratified data was available, males were at a higher risk of death. Also, post-menopausal women are at increased risk of severe COVID-19. However, the biological underpinnings of this have been less visible.

4 Aug 2020

War of sugars - estrogen provides protection in COVID-19

Now a new study published on the preprint server bioRxiv in July 2020 reports that sex hormones could affect the function of the fusion protein that is dependent upon the human ACE2 receptor, thus preventing the entry of the virus into the host cell.

31 Jul 2020

Sex lives of leeches can shed light on endocrine disrupting chemicals

Today, we pull the veil back on the secret sex lives of leeches and how researchers at McMaster University and Fisheries and Oceans Canada are using that information to learn about endocrine disrupting chemicals.

21 Jul 2020