Sickle Cell Anemia News and Research

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Sickle cell anemia is a serious disease in which the body makes sickle-shaped red blood cells. “Sickle-shaped” means that the red blood cells are shaped like a "C." Normal red blood cells are disc-shaped and look like doughnuts without holes in the center. They move easily through your blood vessels. Red blood cells contain the protein hemoglobin. This iron-rich protein gives blood its red color and carries oxygen from the lungs to the rest of the body. Sickle cells contain abnormal hemoglobin that causes the cells to have a sickle shape. Sickle-shaped cells don’t move easily through your blood vessels. They’re stiff and sticky and tend to form clumps and get stuck in the blood vessels. (Other cells also may play a role in this clumping process.) The clumps of sickle cells block blood flow in the blood vessels that lead to the limbs and organs. Blocked blood vessels can cause pain, serious infections, and organ damage.
First ever American gene-editing treatment using CRISPR for genetic disease

First ever American gene-editing treatment using CRISPR for genetic disease

Single-cell encapsulation technology can protect transplanted MSCs from immune attack

Single-cell encapsulation technology can protect transplanted MSCs from immune attack

Three signs of real progress against sickle cell disease

Three signs of real progress against sickle cell disease

More screening and new treatments needed for sickle cell disease

More screening and new treatments needed for sickle cell disease

New gene therapy cures babies with fatal 'Bubble Boy' disease

New gene therapy cures babies with fatal 'Bubble Boy' disease

Cancer patients and those with anemia should not be denied opioids, says CDC

Cancer patients and those with anemia should not be denied opioids, says CDC

Deadly inherited blood disorders cured with bone marrow transplant

Deadly inherited blood disorders cured with bone marrow transplant

Research shows how common fungus gets the flexibility to live in different host environments

Research shows how common fungus gets the flexibility to live in different host environments

Antibody-based treatment could improve cure rate for blood and immune disorders

Antibody-based treatment could improve cure rate for blood and immune disorders

Advances in gene therapy for inherited blood disorders

Advances in gene therapy for inherited blood disorders

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

Daily hydroxyurea treatment may bring some relief for African children with sickle cell anemia

Daily hydroxyurea treatment may bring some relief for African children with sickle cell anemia

Johns Hopkins researchers report challenges in treating severe crisis pain of sickle cell disease

Johns Hopkins researchers report challenges in treating severe crisis pain of sickle cell disease

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

CRISPR-Cas9 technique may raise cancer risk

CRISPR-Cas9 technique may raise cancer risk

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

New discovery may offer insight into treating sickle cell anemia and other blood disorders

New discovery may offer insight into treating sickle cell anemia and other blood disorders

Human genome is like a time machine, says researcher

Human genome is like a time machine, says researcher

Study: Most children with sickle cell anemia not getting daily antibiotics to reduce the risk

Study: Most children with sickle cell anemia not getting daily antibiotics to reduce the risk