Ulcerative Colitis News and Research

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Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
Researchers map bone-marrow microenvironment to shed new light on leukemia

Researchers map bone-marrow microenvironment to shed new light on leukemia

EU-funded project works to better understand human and parasite interactions

EU-funded project works to better understand human and parasite interactions

Onset of inflammatory bowel disease in adulthood tied to higher mortality

Onset of inflammatory bowel disease in adulthood tied to higher mortality

Adult-onset inflammatory bowel disease tied to higher mortality

Adult-onset inflammatory bowel disease tied to higher mortality

Over-fed bacteria in the gut promote disease development

Over-fed bacteria in the gut promote disease development

Study reveals increased risk of cancer, early death in young patients with inflammatory bowel disease

Study reveals increased risk of cancer, early death in young patients with inflammatory bowel disease

Physicians turning to antibiotic alternatives for long-term acne treatment

Physicians turning to antibiotic alternatives for long-term acne treatment

Patent-pending probiotic could help patients with gastrointestinal diseases avoid harmful biofilms

Patent-pending probiotic could help patients with gastrointestinal diseases avoid harmful biofilms

Surprising discovery offers clues to limit graft-vs.-host disease

Surprising discovery offers clues to limit graft-vs.-host disease

Avocado seed extract could be potential source for novel anti-inflammatory compounds

Avocado seed extract could be potential source for novel anti-inflammatory compounds

Fecal transplantation improves the gut of IBS patients

Fecal transplantation improves the gut of IBS patients

Low-calorie 'fasting-mimicking' diet has potential to treat people with IBD

Low-calorie 'fasting-mimicking' diet has potential to treat people with IBD

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

Therapeutic endoscopy has an expanding role in the treatment of IBD

Therapeutic endoscopy has an expanding role in the treatment of IBD

Study finds underutilization of aspirin to prevent colorectal cancer in high risk patients

Study finds underutilization of aspirin to prevent colorectal cancer in high risk patients

American Gastroenterological Association announces 2019 recipients of annual recognition awards

American Gastroenterological Association announces 2019 recipients of annual recognition awards

Study opens new avenue for treating ulcerative colitis or Crohn's disease

Study opens new avenue for treating ulcerative colitis or Crohn's disease

Cells in the intestines play key role in inducing acute inflammatory episodes

Cells in the intestines play key role in inducing acute inflammatory episodes

Fecal transplant from certain donors better than others

Fecal transplant from certain donors better than others

Researchers uncover specific microbial signatures of intestinal disease

Researchers uncover specific microbial signatures of intestinal disease