Ulcerative Colitis News and Research

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Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
New insights into how immune system and inflammation play a role in PD

New insights into how immune system and inflammation play a role in PD

UC researcher finds new treatment option for liver transplant patients

UC researcher finds new treatment option for liver transplant patients

Work in progress on medicine for treatment of ulcerative colitis

Work in progress on medicine for treatment of ulcerative colitis

IBD far more common than expected, and will only increase in future

IBD far more common than expected, and will only increase in future

Healthiest gut bacteria with plant-based or Mediterranean diet

Healthiest gut bacteria with plant-based or Mediterranean diet

Study explores steroid prescribing rates for patients with inflammatory bowel disease

Study explores steroid prescribing rates for patients with inflammatory bowel disease

Study receives NCI grant to explore better treatment for brain tumors in children

Study receives NCI grant to explore better treatment for brain tumors in children

Study identifies genetic marker which could personalize treatment for Crohn's disease

Study identifies genetic marker which could personalize treatment for Crohn's disease

Common genetic variant explains why immunotherapy often fails in Crohn's disease

Common genetic variant explains why immunotherapy often fails in Crohn's disease

Diet low in fermented carbs improves quality of life for patients with IBD

Diet low in fermented carbs improves quality of life for patients with IBD

Diet low in fermented carbohydrates improves health-related quality of life in IBD patients

Diet low in fermented carbohydrates improves health-related quality of life in IBD patients

Common IBD drugs not linked to increased risk of serious infections in children

Common IBD drugs not linked to increased risk of serious infections in children

Walnut consumption may offer protection against ulcerative colitis, study finds

Walnut consumption may offer protection against ulcerative colitis, study finds

Study evaluates the effect of smoking status on disease outcomes in ulcerative colitis

Study evaluates the effect of smoking status on disease outcomes in ulcerative colitis

Edinburgh has highest known rates of inflammatory bowel disease

Edinburgh has highest known rates of inflammatory bowel disease

Genetically tweaking gut bacteria reduces risk of colorectal cancer in mice finds study

Genetically tweaking gut bacteria reduces risk of colorectal cancer in mice finds study

Scientists identify new biomarkers for IBS in urine

Scientists identify new biomarkers for IBS in urine

Researchers find a way to divide patients with ulcerative colitis into groups

Researchers find a way to divide patients with ulcerative colitis into groups

Scientists describe microbiome composition in patients suffering from IBD and PSC

Scientists describe microbiome composition in patients suffering from IBD and PSC

Study: Biologic therapy did not reduce IBD-related hospitalizations and surgeries

Study: Biologic therapy did not reduce IBD-related hospitalizations and surgeries