Ulcerative Colitis News and Research

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Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
Poo transplant can successfully treat patients with ulcerative colitis

Poo transplant can successfully treat patients with ulcerative colitis

Scientists find link between colitis and colon cancer

Scientists find link between colitis and colon cancer

AGA's new clinical guideline to help manage patients with mild-to-moderate ulcerative colitis

AGA's new clinical guideline to help manage patients with mild-to-moderate ulcerative colitis

Women with IBD have increased risk of developing mental illness, finds study

Women with IBD have increased risk of developing mental illness, finds study

Microbial metabolite from pomegranates can reduce and protect against IBD

Microbial metabolite from pomegranates can reduce and protect against IBD

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Allen Institute for Immunology to partner with CU Anschutz to understand dynamics of human immune system

Allen Institute for Immunology to partner with CU Anschutz to understand dynamics of human immune system

Allen Institute for Immunology: A new division focused on human immune system

Allen Institute for Immunology: A new division focused on human immune system

Men with inflammatory bowel disease have higher prostate cancer risk

Men with inflammatory bowel disease have higher prostate cancer risk

TARGET PharmaSolutions and Bristol Myers Squibb partner to advance IBD research

TARGET PharmaSolutions and Bristol Myers Squibb partner to advance IBD research

Cellix Bio announces completion of Pre-IND meeting with FDA on novel prodrug of mesalamine for ulcerative colitis

Cellix Bio announces completion of Pre-IND meeting with FDA on novel prodrug of mesalamine for ulcerative colitis

AbbVie’s U-ACHIEVE Phase 2b/3 dose-ranging study improves outcomes in patients with ulcerative colitis

AbbVie’s U-ACHIEVE Phase 2b/3 dose-ranging study improves outcomes in patients with ulcerative colitis

Breathing through the nose improves memory consolidation

Breathing through the nose improves memory consolidation

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

Gilead Sciences presents Phase 3 results of filgotinib in biologic-experienced rheumatoid arthritis at 2018 ACR/ARHP Annual Meeting

Gilead Sciences presents Phase 3 results of filgotinib in biologic-experienced rheumatoid arthritis at 2018 ACR/ARHP Annual Meeting

Study reports increased risk of death in children with inflammatory bowel disease

Study reports increased risk of death in children with inflammatory bowel disease

International audit of colorectal surgeries provides highly realistic reflection of current practices

International audit of colorectal surgeries provides highly realistic reflection of current practices

Understanding immune system's balancing act could help in prevention, treatment of IBD

Understanding immune system's balancing act could help in prevention, treatment of IBD

TGHRI scientists detail role of insulin as a boost to the immune system

TGHRI scientists detail role of insulin as a boost to the immune system

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes