Ulcerative Colitis News and Research

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Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

New study shows how the immune system regulates gut fungal population

New study shows how the immune system regulates gut fungal population

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

Researchers design electronic nose to sniff out colon diseases

Researchers design electronic nose to sniff out colon diseases

Specific diets may help prevent colorectal cancer in high-risk groups

Specific diets may help prevent colorectal cancer in high-risk groups

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Scientists develop new, high resolution method for identifying microbial species and strains

Scientists develop new, high resolution method for identifying microbial species and strains

Blood test using infrared spectroscopy can help detect two cancer types

Blood test using infrared spectroscopy can help detect two cancer types

Study finds increasing incidence of inflammatory bowel disease in newly industrialized countries

Study finds increasing incidence of inflammatory bowel disease in newly industrialized countries

Studies offer evidence that exercise alone can change composition of gut microbes

Studies offer evidence that exercise alone can change composition of gut microbes

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

Inflammatory bowel disease patients over the age of 60 often receive older drugs

Inflammatory bowel disease patients over the age of 60 often receive older drugs

Ozanimod effective against multiple sclerosis, enters New Drug Approval process with FDA

Ozanimod effective against multiple sclerosis, enters New Drug Approval process with FDA

Breakthrough discovery could lead to better treatments for colon cancer, gut diseases

Breakthrough discovery could lead to better treatments for colon cancer, gut diseases

Study finds more patients with ulcerative colitis but less number of surgeries

Study finds more patients with ulcerative colitis but less number of surgeries

Study findings provide new insight into inflammatory bowel disease

Study findings provide new insight into inflammatory bowel disease

Crohn's & Colitis Foundation and Oxford University Press partner to publish Inflammatory Bowels Diseases journal

Crohn's & Colitis Foundation and Oxford University Press partner to publish Inflammatory Bowels Diseases journal

Study provides new insights into biologic networks involved in IBD

Study provides new insights into biologic networks involved in IBD

Gut bacteria in Hadza diet different from ours study finds

Gut bacteria in Hadza diet different from ours study finds

Blood test using infrared spectroscopy could provide cheaper, quicker alternative for colitis screening

Blood test using infrared spectroscopy could provide cheaper, quicker alternative for colitis screening