Ulcerative Colitis News and Research

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Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
Researchers reveal potent new mechanism of action for treatment of IBD

Researchers reveal potent new mechanism of action for treatment of IBD

Celltrion Healthcare advocates early introduction of biologics for patients to improve clinical outcomes

Celltrion Healthcare advocates early introduction of biologics for patients to improve clinical outcomes

Study: Psoriasis patients taking Humira show no change in aortic inflammation

Study: Psoriasis patients taking Humira show no change in aortic inflammation

Scientists develop integrated system for early diagnosis of diseases using wearable monitors

Scientists develop integrated system for early diagnosis of diseases using wearable monitors

Study points to new treatments for incurable bowel conditions

Study points to new treatments for incurable bowel conditions

Single FMT enema produces sustained and significant improvements in cognitive function

Single FMT enema produces sustained and significant improvements in cognitive function

Analysis does not reveal consistent link between NSAIDs use and exacerbation of inflammatory bowel disease

Analysis does not reveal consistent link between NSAIDs use and exacerbation of inflammatory bowel disease

University Hospitals study suggests strong connection between IBD and heart attacks

University Hospitals study suggests strong connection between IBD and heart attacks

IQuity launches pioneering RNA-based blood test to diagnose fibromyalgia

IQuity launches pioneering RNA-based blood test to diagnose fibromyalgia

Inflammatory bowel disease linked to elevated risk of heart attack

Inflammatory bowel disease linked to elevated risk of heart attack

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Impairing rare group of intestinal cells allows gut bacteria to cause inflammation, study finds

Impairing rare group of intestinal cells allows gut bacteria to cause inflammation, study finds

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

New study shows how the immune system regulates gut fungal population

New study shows how the immune system regulates gut fungal population

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

Researchers design electronic nose to sniff out colon diseases

Researchers design electronic nose to sniff out colon diseases

Specific diets may help prevent colorectal cancer in high-risk groups

Specific diets may help prevent colorectal cancer in high-risk groups

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Scientists develop new, high resolution method for identifying microbial species and strains

Scientists develop new, high resolution method for identifying microbial species and strains

Blood test using infrared spectroscopy can help detect two cancer types

Blood test using infrared spectroscopy can help detect two cancer types