Ulcerative Colitis News and Research

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Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
Experts examine stool protein biomarkers that indicate inflammatory bowel disease

Experts examine stool protein biomarkers that indicate inflammatory bowel disease

Strawberries could mitigate colonic inflammation

Strawberries could mitigate colonic inflammation

Understanding How Antibodies Shape the Gut Microbiome

Understanding How Antibodies Shape the Gut Microbiome

Researchers discover new protein that controls level of inflammation-inducing molecule

Researchers discover new protein that controls level of inflammation-inducing molecule

Long-lasting HIV control without antiretroviral therapy is a feasible goal, says expert

Long-lasting HIV control without antiretroviral therapy is a feasible goal, says expert

Scientists find key link between viruses and inflammatory bowel diseases

Scientists find key link between viruses and inflammatory bowel diseases

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Study offers new hope for people with disabling Dupuytren's disease

Study offers new hope for people with disabling Dupuytren's disease

Key innovations awards recognize PENTAX Medical for new product developments

Key innovations awards recognize PENTAX Medical for new product developments

Researchers discover immune cells that create and sustain chronic inflammatory bowel disease

Researchers discover immune cells that create and sustain chronic inflammatory bowel disease

Biosimilar competition may offer hope for cheaper, better psoriasis treatments in the future

Biosimilar competition may offer hope for cheaper, better psoriasis treatments in the future

Microbiotica partners with University of Adelaide to develop defined bacterial product for ulcerative colitis

Microbiotica partners with University of Adelaide to develop defined bacterial product for ulcerative colitis

Faeces donors do it out of willingness not money - study

Faeces donors do it out of willingness not money - study

Cedars-Sinai study identifies gut gas associated with diarrhea

Cedars-Sinai study identifies gut gas associated with diarrhea

Novel PET imaging shows promise for noninvasively detecting inflammation in people with IBD

Novel PET imaging shows promise for noninvasively detecting inflammation in people with IBD

Study: People taking immunosuppressant drugs less likely to develop Parkinson's disease

Study: People taking immunosuppressant drugs less likely to develop Parkinson's disease

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

Researchers reveal potent new mechanism of action for treatment of IBD

Researchers reveal potent new mechanism of action for treatment of IBD