Since its launch in 2009, the Cubis® balance family has set the standard for high-performance laboratory weighing, making it the preferred option for scientists and quality experts who cannot compromise on data integrity or regulatory compliance.
Each generation has redefined what a balance is capable of, combining exceptional metrological performance with the connectivity, intelligence, and vision required by Lab 4.0. Cubis® III establishes a new benchmark for simple, transparent, and direct integration, as well as built-in compliance, with no middleware and no hidden costs.
What users can expect right away:
- Uncompromising accuracy: Best-in-class weighing performance ensures accurate and consistent results
- Direct connectivity: Connect easily with any open digital medium
- Built-in compliance: Two models: Cubis® III for non-regulated labs and Cubis® III Max for regulated environments
- Scalable design: Begin with a single instrument, then replicate configurations to create a linked, compliant fleet
Cubis® III weighing portfolio
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Ultra-micro and micro configurable lab balances
Used to determine the exact weight of the smallest quantities.
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- Readability: 0.1 µg to 1 µg
- Maximum capacity: 2.1 g to 10.1 g
The Sartorius Cubis® III ultra-micro and micro balances provide precise and accurate results for microgram-level research. This completely flexible portfolio focuses on the most demanding microweighing operations, with application-driven hardware and software to fulfill specific procedures and compliance needs.
Why choose Cubis® III for ultra‑micro and micro weighing?
- 0.1 µg readability for trace-level mass: Obtain the best possible analytical findings with readability up to 0.0001 mg (0.1 µg) for critical assays and small sample differentials.
- Capacity suited to the samples: Choose models with a maximum capacity of 2.1 g to 10.1 g to handle everything from standards and microformulations to filter and particulate weighing.
- Purpose-built configuration: Select only the required ultra-micro/micro modules, draft‑shield and weighing pan options, specific applications, and connectivity.
- Automatic, motorized, round glass draft shield with learning capabilities, illumination, and an integrated motion sensor
- Manual stainless steel draft shield for filter weighing applications
- Simple, guided operation: Every Cubis® III micro and ultra-micro module is engineered for easy operation. Correct setup, early problem identification, and fewer handling mistakes are all supported by intelligent diagnostics.
- Repeatable performance: Repeatability in micro-scale measurements is strengthened by robust mechanics and smart procedures that produce consistent findings across users and shifts.
- Built-in compliance by design: Software and documentation features assist data integrity and regulatory procedures in GxP environments, while adhering to internal SOPs and external standards.
High-capacity micro and semi-micro configurable lab balances
Measure small sample weights with high accuracy.
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- Readability: 1 µg to 0.01 mg
- Maximum Capacity: 21 g to 220 g
Regulations require precise weighing, data integrity, and audit readiness. The Cubis® III high-capacity micro and semi-micro balancing range makes this easier to achieve.
Cubis® III is designed for compliance and configurability, providing micro or semi-micro readability with straightforward operation, intelligent diagnostics, and contemporary interfaces that improve repeatability, mitigate human error, and expedite regular tasks.
Why choose Cubis® III for micro or semi‑micro weighing?
- Micro or semi‑micro ranges for regulated labs: The system delivers the accuracy, precision, and dependability required while facilitating end-to-end traceability and audit-ready records.
- Configurable to the methods: Hardware and software are customizable to fit specific processes, draft-shield and weighing pan choices, apps, and connectivity, ensuring customers only pay for what is required.
- Automatic glass draft shield with or without integrated ionizer for removing interfering electrostatic charges from samples and sample containers
- Manual glass draft shield with smooth-action doors
- Intuitive operation with fewer errors: Guided interfaces and sophisticated diagnostics assist users in properly configuring the system, detecting difficulties early, and minimizing handling mistakes.
- Higher repeatability across users: Even in multi-shift settings, daily consistency is enhanced by strong mechanics and established procedures.
- Built-in compliance: GxP procedures, data management and integrity, electronic records and signatures, and compliance with EU Annex 11 and 21 CFR Part 11 are all supported.
- Ready for integration: Easy process integration and effective data transmission are supported by seamless connectivity and communication choices.
One display for all new Cubis® III balances
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With a single, universal display, users can streamline and unify the weighing experience throughout the Cubis® III portfolio. This user-friendly interface standardizes operation for the various Cubis® III balances: high-capacity, precision, analytical, semi-micro, high-capacity micro, micro, and ultra-micro.
This promotes consistency, reduces training time, and supports compliance and data integrity from setup to results. It was created for regulated R&D and QC labs.
Highlights of the Cubis® III universal display
- One interface across every model: Methods and user experience are standardized across all new Cubis® III balances, reducing variability and streamlining SOPs.
- Intuitive, modern touchscreen: Users enjoy quicker operation with fewer mistakes, thanks to the ergonomic interaction, clear navigation, and guided prompts.
- Intelligent diagnostics: Stable, repeatable outcomes and early problem identification are supported by environmental inspections, setup instructions, and status monitoring.
- Seamless connectivity: Flexible data interchange and peripheral support for interfacing with digital systems, printers, and scanners enable effective documentation.
- Configurable apps and workflows: Adapt application modules to the procedures so the display corresponds with the procedures and changes as requirements evolve.
- Compliance‑support features: Designed for audit-ready traceability in accordance with GxP procedures, data integrity standards, and electronic records/e-signature processes.
Analytical and milligram configurable lab balances
Ideal for highly precise measurements of small samples.
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- Readability: 0.1 mg to 1 mg
- Maximum Capacity: 120 g to 5200 g
Accuracy, data integrity, and audit-ready traceability are crucial when weighing in regulated contexts. These requirements are met by the Sartorius Cubis® III analytical and milligram balance range.
Cubis® III supports pharmaceutical and GxP compliance while improving repeatability, minimizing human error, and streamlining analytical workflows with its programmable hardware and software, user-friendly interfaces, and intelligent diagnostic systems.
Why choose Cubis® III for analytical and milligram weighing?
- Analytical and milligram readabilities for regulated laboratories: Provide accurate findings while upholding full documentation and traceability.
- Adaptable to different techniques: Choose the precise set of modules and applications that the SOPs specify.
- To remove interfering electrostatic charges from samples and sample containers, an automatic glass draft shield with or without an integrated ionizer (only analytical)
- Manual glass draft shield with smooth-action doors
- Intuitive operation with fewer errors: By assisting users in accurately setting up and working with confidence, modern user interfaces and guided procedures reduce variability.
- Intelligent diagnostics: Early problem detection and consistent, repeatable outcomes are supported by built-in monitoring and advice.
- Support for compliance by design: Features that support data handling, data integrity, and electronic records/e-signatures for 21 CFR Part 11 and EU Annex 11 align with GxP standards.
- Smooth connectivity and integration: Process integration and documentation are made easier by effective data interchange, peripheral support, and adaptable communication choices.
- Ergonomic sample handling: Careful planning simplifies repetitive processes and promotes measurement uniformity among users and shifts.
Precision configurable lab balances
Handle larger sample sizes compared to analytical balances.
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- Readability: 1 mg to 100 mg
- Maximum Capacity: Up to 14.2 kg
The Cubis® III precision balance range offers the appropriate weighing range, offering flexibility to select the precise model that matches the load size, vessel dimensions, and process requirements, without compromising repeatability, usability, or compliance. It is designed for workflows that require medium-to-large sample quantities and container taring from hundreds of grams to the kilogram range.
Why choose Cubis® III for the precision weighing range?
- Wide capacity coverage: Choose a capacity that can accommodate everything from huge vessels and containers to benchtop beakers and trays, ranging from 320 g to 14,200 g.
- Fit-for-purpose readability: For medium-to-large samples and additions, choose readabilities from 1 mg to 100 mg.
- Designed for vessels and containers: A sturdy weighing pan, ergonomic handling, and guided operation make taring and dosing easier and more efficient.
- For precision balances with readability of 1 mg:
- Easy-to-use manual glass draft shield.
- Removable flat stainless steel draft shield frame (not shown in the picture)
- Precision balances with readabilities of 10 mg and 100 mg lack a draft shield
- Consistency with greater loads: Intelligent diagnostics and guided tests contribute to stability and reproducibility over the whole capacity range.
- Compliance‑ready workflows: Support for pharmaceutical and GxP practices, including data handling, data integrity, connectivity, and traceability.
- Configurable platform: Customize hardware and software applications so each balance matches the weighing range, SOPs, and integration requirements.
High-capacity balances
Designed to accurately measure high-capacity load.
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- Readability: 100 mg to 1 g
- Maximum Capacity: 11.2 kg to 70.2 kg
Cubis® III high-capacity balances provide consistent findings for large sample amounts and weighty containers. These balances are designed for heavy-duty lab and process weighing, offering a wide weighing range and practical ergonomics.
Why choose Cubis® III high‑capacity balances?
- Built for huge loads and high tares: The system is designed for weighing large sample volumes or heavy containers directly on the weighing pan while maintaining precision.
- The flat 400 × 300 mm stainless-steel weighing pan offers secure support for drums, buckets, trays, and big containers.
- Ergonomic, flexible operation: The display can be detached from the weighing module and set on a stand for improved visibility and handling of large goods
- Workflow-ready software supports popular high-capacity weighing applications, speeding up regular procedures and reducing mistakes.
Two packages: One performance standard
All balances are offered as Cubis® III or Cubis® III Max to meet a variety of applications, so users can select the correct fit for their labs. Both products provide the same class-leading weighing performance; the difference is the lab's degree of compliance and integration support.
Users can upgrade to Cubis® III Max at any moment as their requirements change.
Cubis® III: Standalone optimized
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Best-in-class weighing performance and robust standalone operation
- Delivers precise, dependable weighing with complete process control
- Flexible documentation possibilities, from print to digital
- Integrated user management with RFID-based, one-tap login
- Safeguards weighing through guided procedures and validated calibration
Scale when ready
- Digital-driven performance: Top-tier accuracy and proven dependability, ready to use right out of the box
- Designed for non-regulated labs: Ideal for labs that require precise and secure weighing: no compliance burden, no extra complexity
- Future-proof: Expandable compliance features and enhanced connection options as needed
Accuracy first. Compliance when ready
Users can choose uncompromising accuracy and simple operation, knowing that they can add compliance and connectivity later.
Cubis® III Max: Integration optimized
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Best-in-class weighing performance designed for connected and regulated laboratories
- Engineered for the most demanding regulated situations in pharmaceuticals, medical devices, and beyond
- Comprehensive connectivity: from basic result transfer to complete system integration
- Allows automation of complicated procedures right on the balance
- Designed for easy worldwide deployment across several sites with little IT effort
Enterprise compliance and scale
- Beyond hardware: Provides a compliant end-to-end solution without any extra middleware, from safe data production to smooth integration
- More than just connectivity: Well-suited for digitally evolved enterprises that want complete compliance, automated workflows, and enterprise-grade connectivity
Compliance is built in and connected from day one
Users can decide if they require established processes, centralized control, and automated data flows across various sites or systems.
Cubis® III: Native connectivity, compliant, middleware-free
Direct connectivity
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The Cubis® III lab balance portfolio provides best-in-class weighing with complete data governance, without any hidden middleware costs, by connecting natively to the digital environment and simplifying integration from the start.
Native connectivity with inbuilt OPC UA provides real-time LIMS/MES/ERP connections; prebuilt connectors to LIMS/ELN/CDS. Supports HTTPS/FTPS/SMB, SICS/SBI, RS232/USB/Ethernet/Wi-Fi, and TXT/CSV/PDF outputs, allowing for compliant electronic documentation out of the box.
Full compliance
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Cubis® III Max provides turnkey compliance for regulated performance-driven laboratories by unifying all of the requirements for audit-ready operation into a single, independent solution, with no additional software or middleware required.
Native 21 CFR Part 11 features include a secure audit trail, tamper-proof records with metadata, integrated electronic signatures, and extensive, adjustable user and role management that adapts to the rules and processes.
It also provides RFID login, LDAP directory connectivity, and automated NTP time synchronization. The approach adheres to USP and main pharmacopeias (Ph.Eur., JP, ChP) while enforcing minimal weight.
Enterprise-grade processes lessen cybersecurity risk. The Cleaning QApp enables SOP-aligned cleaning with electronic sign-off for total traceability and audit preparedness.
Real savings
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Cubis® III can be integrated into the laboratory’s IT or run on its own. This removes middleware, additional licensing, and costly infrastructure, lowering the overall cost of ownership throughout the lifespan.
It provides reliable findings with small sample sizes, saving money on expensive ingredients and promoting sustainability. Modular hardware and software allow users to adjust and extend over time while maintaining complete control over the investment.
Applications for Cubis® III lab balances
Pharma-compliant weighing
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Compliance with regulatory regulations is the most reliable assurance of product safety, effectiveness, and process efficiency in the pharmaceutical industry. Discover how Cubis® III balances provide excellent performance, exceed regulatory standards, and facilitate safe workflow management throughout everyday weighing activities.
Infusion pump testing and micro-flow calibration
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The Cubis® III suite supports extremely high-resolution weighing for precise flow-rate evaluation and regulatory compliance. These balances are designed to ensure accurate dosage administration for devices such as infusion pumps, assisting specialists in product development, quality assurance, regulatory relations, and other fields.
Medical device quality control
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Precision weighing scales for drug-eluting stents provide precise, dependable results while increasing production. Cubis® III balances increase throughput while maintaining high accuracy.
Chemical and consumer care
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Organic impurities can arise during the manufacturing process and storage of a product. Sample preparation is a critical step in identifying these process-related contaminants. Cubis® III premium ultra-micro, micro, and high-capacity micro balances are appropriate for sample preparation in analytical applications that require extremely small sample volumes (for example, elemental analysis).