Meeting the routine demands of quantitative LC-MS/MS in clinical settings is essential for reliable measurement and accurate patient results.
Utilizing the ACQUITY UPLC I-Class PLUS/Xevo TQD IVD System, the clinical laboratory can fulfill its routine quantification needs more efficiently than before. Expedite method development for both sensitive and robust methodologies. Simplify processes and enhance user-friendliness. Optimize throughput and operational time with the unmatched durability of our adaptable LC-MS/MS.
Overview
- Enhance workflow and data transfer by integrating with liquid-handling robots and the HL7-compliant MassLynx LIMS Interface.
- Guarantee reproducible outcomes even in challenging matrices and conserve time with minimal maintenance and straightforward cleaning procedures.
- Receive priority on-site support, a two-hour callback, a 48-hour on-site response, and sustain system uptime with FlexCHOICE: mySystem Coverage Solutions.
- From the moment of sample injection to the reporting of results, user-friendly informatics software solutions empower users to manage user access, oversee the system, and effectively process and review the results.
- Achieve the highest level of selectivity and robustness required for the routine quantification of the most prevalent LC-MS/MS tests, thereby ensuring optimal productivity with minimal effort in the clinical laboratory.
Recommended Use: For the measurement of analytes in patient samples within a standard clinical laboratory setting.
ACQUITY UPLC I-Class PLUS IVD Flexible Options
Column Manager
Link several columns that will automatically adjust based on the analysis being conducted – enhancing the efficiency and conserving time.
Column Heater
A single-column heater is perfect for dedicating the system to a specific type of analysis and for fulfilling workflow needs.
Sample Organizer
- For examining a substantial quantity of samples, the Sample Organizer is an ideal choice.
- The Sample Organizer will ensure that the analysis continues seamlessly, even in the absence, by automatically loading the plates into the instrument for evaluation, featuring a significant plate capacity.
Sample Manager FTN or FL
- Attain versatility in sample injection for applications.
- Achieve the minimal inject-to-inject cycle times with a loop-based injector.
- Optimize the injection volume range from 0.1 to 1000 µL using a needle-in-flow path injector.
- Guarantee compatibility with the most sensitive mass spectrometers through programmable method settings and ultra-low carryover.
Solving challenging, complex separations
Maximize the information obtained from the sample and expedite laboratory results using the ACQUITY UPLC I-Class PLUS. This leading-edge separation technology offers a robust solution for the most essential clinical samples. Accelerate access to vital data by reducing analysis time, enhancing laboratory productivity, and enabling faster decision-making for improved patient care.

Image Credit: Waters
Intuitive informatics solutions
Compliant, user-friendly software that enables rapid, reliable decision-making in a clinical laboratory setting is essential. Scientists must be able to deliver prompt, precise results while ensuring sample traceability. MassLynx (IVD) Mass Spectrometry Software, along with the TargetLynx XS (IVD) Application Manager, enhances the efficiency with which users can transform the sample data into valuable insights.
- Control instruments, acquire data, and process information utilizing Waters LC-MS/MS in vitro diagnostic systems.
- Convert LC-MS/MS data into practical, significant results for quantitative analysis with the TargetLynx Application Manager.
- A user-friendly interface, focused on the MassLynx Sample List stream, streamlines interactions with the Waters LC-MS/MS system by providing a single point for initiating all tasks related to system control, sample information entry, and data processing.
Minimize maintenance
The durable design of the Xevo source necessitates minimal maintenance and eliminates the requirement to vent the instrument, thereby maximizing instrument availability. There is no need to be concerned about lengthy optimization processes with any tools.
The replacement of the probe assembly, including the capillary, is completely tool-free, ensuring you achieve the desired results on the first attempt, without complications, regardless of who operates and maintains the instrument.
Enhance data workflow solutions
The MassLynx LIMS interface adheres to Health Level 7 (HL7) protocols and automates the exchange of information with an external LIMS provider, thereby enhancing data workflow and reducing transcription errors.
The MassLynx Tecan File converter, along with a direct connection to Hamilton automatic liquid handlers, enables sample tracking from the primary tube to the final result without operator intervention, ensuring secure data transfer and further minimizing transcription errors.
Flexible service options
Tailor the performance maintenance appointments with Waters FlexCHOICE: mySystem Coverage. The coverage is structured to ensure consistent performance, maintenance visits, and a guaranteed on-site response if remote technical assistance fails to resolve a system problem. We recognize that instrument performance, operational uptime, and cost management are essential for clinical diagnostics laboratories.
Waters, Xevo, MassTrak, ACQUITY, and UPLC are trademarks of Waters Corporation or its affiliates.