Biochemistry

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Scientists reveal the possibility to improve immunological memory in vaccines

A key transcription factor in T-cell immunology is crucial to the immune system's "memory" in recognizing threats it has already faced before – and it may be possible to improve this immunological memory in vaccines, according to a new paper by scientists at the Hackensack Meridian Center for Discovery and Innovation.

24 Feb 2022

Researchers show how the biological system can be steered with artificial organic neurons

For the first time, researchers demonstrate an artificial organic neuron, a nerve cell, that can be integrated with a living plant and an artificial organic synapse.

23 Feb 2022

Why is it Important to Democratize Proteomics Data?

In this interview, we speak to Steve Kosteski from IsoPlexis about the importance of single-cell proteomics within the life sciences sector.

From Society for Laboratory Automation and Screening (SLAS) 23 Feb 2022

Accelerating genomics research with the firefly

In this interview, we speak to Paul Lomax from SPT Labtech about their new firefly platform and how it will help to accelerate genomics research.

From SPT Labtech 23 Feb 2022

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Multiple myeloma (MM) is a largely incurable cancer of plasma cells with an extremely poor prognosis. However, investigators from Japan have recently found that a common component of amino acid transporters, CD98 heavy chain, represents an effective monoclonal antibody target in treating MM.

22 Feb 2022

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Researchers at The University of Texas MD Anderson Cancer Center have developed a new radio-labeled molecule capable of selectively reacting with certain high-energy radicals that are characteristic of innate immune activity, which may allow a non-invasive approach to monitor inflammation in real time by positron emission tomography (PET) imaging.

21 Feb 2022

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

A 'waste collection' tidies up our cells. If something does not go according to plan, serious diseases such as Alzheimer's or Parkinson's may develop.

20 Feb 2022

Structure of protein that can pump toxic molecules out of bacterial cells revealed

MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria become resistant to multiple antibiotics.

18 Feb 2022

Certain flavonoids inhibit an enzyme involved in the formation of key hormone in yellow fever mosquito

When most people think of flavonoids, natural compounds found in plants and other organisms, their nutritional benefits probably come to mind first.

17 Feb 2022

Developing nanoplatforms for direct drug delivery to T cells

T cells, also known as lymphocytes, have important roles in various immune reactions. However, there are only a few reports on delivery systems into T cells. Realizing this, it is essential to work and actively contribute in controlling immune systems.

16 Feb 2022

Cells self-organize to generate forces that model the shapes of tissues

A team from the UNIGE has demonstrated that cells self-organise to generate forces that model the shapes of our tissues.

12 Feb 2022

Study reports accumulation of SARS-CoV-2 RNA in sewer biofilms

During the COVID-19 pandemic, monitoring the levels of SARS-CoV-2 RNA in wastewater entering treatment plants has been one way that researchers have gauged the disease's spread.

10 Feb 2022

Study provides new understanding of caffeine's protective effects on the cardiovascular system

Scientists have a new understanding of the protective effects of caffeine on the cardiovascular system. While its stimulant effects have long been characterized, a team of Canadian researchers have discovered how caffeine interacts with key cellular factors to remove cholesterol from the bloodstream.

10 Feb 2022

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

The fight against the COVID-19 pandemic is an international scientific challenge regarding the search for strategies to fight the viral infection and prevent its damaging consequences.

7 Feb 2022

Selenium could boost learning and memory in aging brains

Selenium – a mineral found in many foods – could reverse the cognitive impact of stroke and boost learning and memory in aging brains, according to University of Queensland research.

7 Feb 2022

Cocktail of two chemicals could help slow down age-related muscular decline

Researchers from Tokyo Metropolitan University have shown that a mixture of 5-aminolevulinic acid(5-ALA) hydrochloride and sodium ferrous citrate (SFC) helps slow down aging-related muscular decline in fruit flies, leading to a slower decline in locomotor activity and longer lifespans.

7 Feb 2022

Researchers find a way to interfere with the energy pathway that promotes liver cancer spread

The World Health Organization projects that starting in 2030, over a million people will die each year from liver cancer.

4 Feb 2022

Spice could play a key role in reducing salt intake among seniors

Montero, M.L., et al. (2022) Saltiness perception in white sauce formulations as tested in older adults. Food Quality and Preference. doi.org/10.1016/j.foodqual.2022.104529.

3 Feb 2022

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

The function of an enzyme, critical to most forms of life, has been revealed.

2 Feb 2022

Study reveals a direct correlation between fat browning and consumption of flavan 3-ols

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria - subcellular organelles associated with energy production - which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

2 Feb 2022

Biochemistry

Scientists reveal the possibility to improve immunological memory in vaccines

Researchers show how the biological system can be steered with artificial organic neurons

Why is it Important to Democratize Proteomics Data?

Accelerating genomics research with the firefly

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

Structure of protein that can pump toxic molecules out of bacterial cells revealed

Certain flavonoids inhibit an enzyme involved in the formation of key hormone in yellow fever mosquito

Developing nanoplatforms for direct drug delivery to T cells

Cells self-organize to generate forces that model the shapes of tissues

Study reports accumulation of SARS-CoV-2 RNA in sewer biofilms

Study provides new understanding of caffeine's protective effects on the cardiovascular system

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

Selenium could boost learning and memory in aging brains

Cocktail of two chemicals could help slow down age-related muscular decline

Researchers find a way to interfere with the energy pathway that promotes liver cancer spread

Spice could play a key role in reducing salt intake among seniors

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

Study reveals a direct correlation between fat browning and consumption of flavan 3-ols

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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