Biochemistry

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Resistance exercise regulates fat cell metabolism at a molecular level, study finds

Findings from a new University of Kentucky College of Medicine and College of Health Sciences study add to growing evidence that resistance exercise has unique benefits for fat loss.

9 Aug 2021

Tiny gel drops for the development of regenerative therapies

Tiny drops that resemble an extracellular matrix can be used to culture cells for delivery into the human body.

9 Aug 2021

Dileucine more effective than leucine in stimulating muscle-building in humans

In a randomized control study of 10 healthy young men, researchers compared how consuming the single amino acid leucine or its two-molecule equivalent, dileucine, influenced muscle-building and breakdown.

9 Aug 2021

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

A group of medications long prescribed to treat tapeworm has inspired a compound that shows two-pronged effectiveness against COVID-19 in laboratory studies, according to a new publication appearing online in the journal ACS Infectious Disease.

9 Aug 2021

Researchers reveal how pneumonia-causing bacteria obtain essential nutrient from our bodies

Australian researchers have revealed how the bacterium Streptococcus pneumoniae (pneumococcus) obtains the essential nutrient, manganese, from our bodies, which could lead to better therapies to target what is a life-threatening, antibiotic-resistant pathogen.

6 Aug 2021

New cargo-carrying nanocontainer constructed entirely from biological components

Nanocontainers can transport substances into cells where they can then take effect. This is the method used in, for example, the mRNA vaccines currently being employed against Covid-19 as well as certain cancer drugs.

6 Aug 2021

New procedure increases the sensitivity to detect viruses in blood samples from healthy people

The Institute for Integrative Systems Biology (I2SysBio), a joint centre of the University of Valencia and the Spanish National Research Council (CSIC), has developed a procedure that increases the sensitivity to detect viruses in blood samples from healthy people, in addition to reducing the effect of contaminations.

6 Aug 2021

Researchers develop a novel process for producing pure RNA

Researchers at the University of Massachusetts Amherst recently unveiled their discovery of a new process for making RNA.

6 Aug 2021

Immune system signaling molecule promotes the production of energy-burning 'beige fat'

An immune signal promotes the production of energy-burning "beige fat," according to a new study publishing August 5th in the open-access journal PLOS Biology by Zhonghan Yang of Sun Yat-Sen University, Guangzhou, China, and colleagues.

5 Aug 2021

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Frequent, rapid testing for COVID-19 is critical to controlling the spread of outbreaks, especially as new, more transmissible variants emerge.

5 Aug 2021

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43.

4 Aug 2021

New review: How chemical reactions can be used to build computing systems

A single molecule contains a wealth of information. It includes not only the number of each kind of constituent atom, but also how they're arranged and how they attach to each other.

3 Aug 2021

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Over the years, significant advancements in cancer research have led us to the next step in cancer therapy – vaccines for cancer! However, the direct use of these vaccines in the affected individuals have often failed to bring about desired anti-tumor effects.

3 Aug 2021

Study paves the way to a new drug design concept

Hydrogen peroxide reacts with copper to produce hydroxyl radicals with strong antibacterial properties. However, this requires high copper concentrations because two copper atoms have to come close together, which occurs by chance.

31 Jul 2021

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

Hokkaido University researchers in Japan created and tested a library of lipid-based compounds to find a way to safely and effectively deliver RNA drugs to the lungs.

30 Jul 2021

The Role of FT-NIR Spectroscopy in Edible Oils and Fats

In this interview, Mickaël Watiez, Head of Research & Development at Lesieur, and Dagmar Behmer, Marketing Manager Applied Spectroscopy at Bruker Optics talk to News-Medical Life Sciences about the role FT-NIR Spectroscopy can play in testing edible oils and fats.

From Bruker Optics 28 Jul 2021

Simple method to assess the risk of vascular inflammation for diabetes patients

A team of international scientists from Nanyang Technological University, Singapore (NTU Singapore), Tan Tock Seng Hospital (TTSH) in Singapore, and the Massachusetts Institute of Technology (MIT) has developed a simple method of extracting tiny biological particles from a person's blood and use them as biomarkers to assess the health of their blood vessels.

27 Jul 2021

Novel microfluidic device used to manipulate major whey protein

After gaining world attention by 'unboiling' egg protein, Flinders University scientists have now used an Australian-made novel thin film microfluidic device to manipulate Beta-lactoglobulin (β-lactoglobulin), the major whey protein in cow's, sheep's and other mammals.

26 Jul 2021

Researchers identify an unexpected effect for already characterized active substances

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021

Scientists uncover the early assembly of gamma-secretase involved in plaque production

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease.

23 Jul 2021

Biochemistry

Resistance exercise regulates fat cell metabolism at a molecular level, study finds

Tiny gel drops for the development of regenerative therapies

Dileucine more effective than leucine in stimulating muscle-building in humans

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

Researchers reveal how pneumonia-causing bacteria obtain essential nutrient from our bodies

New cargo-carrying nanocontainer constructed entirely from biological components

New procedure increases the sensitivity to detect viruses in blood samples from healthy people

Researchers develop a novel process for producing pure RNA

Immune system signaling molecule promotes the production of energy-burning 'beige fat'

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

New review: How chemical reactions can be used to build computing systems

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Study paves the way to a new drug design concept

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

The Role of FT-NIR Spectroscopy in Edible Oils and Fats

Simple method to assess the risk of vascular inflammation for diabetes patients

Novel microfluidic device used to manipulate major whey protein

Researchers identify an unexpected effect for already characterized active substances

Scientists uncover the early assembly of gamma-secretase involved in plaque production

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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