Biochemistry

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Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Frequent, rapid testing for COVID-19 is critical to controlling the spread of outbreaks, especially as new, more transmissible variants emerge.

5 Aug 2021

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43.

4 Aug 2021

New review: How chemical reactions can be used to build computing systems

A single molecule contains a wealth of information. It includes not only the number of each kind of constituent atom, but also how they're arranged and how they attach to each other.

3 Aug 2021

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Over the years, significant advancements in cancer research have led us to the next step in cancer therapy – vaccines for cancer! However, the direct use of these vaccines in the affected individuals have often failed to bring about desired anti-tumor effects.

3 Aug 2021

Study paves the way to a new drug design concept

Hydrogen peroxide reacts with copper to produce hydroxyl radicals with strong antibacterial properties. However, this requires high copper concentrations because two copper atoms have to come close together, which occurs by chance.

31 Jul 2021

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

Hokkaido University researchers in Japan created and tested a library of lipid-based compounds to find a way to safely and effectively deliver RNA drugs to the lungs.

30 Jul 2021

The Role of FT-NIR Spectroscopy in Edible Oils and Fats

In this interview, Mickaël Watiez, Head of Research & Development at Lesieur, and Dagmar Behmer, Marketing Manager Applied Spectroscopy at Bruker Optics talk to News-Medical Life Sciences about the role FT-NIR Spectroscopy can play in testing edible oils and fats.

From Bruker Optics 28 Jul 2021

Simple method to assess the risk of vascular inflammation for diabetes patients

A team of international scientists from Nanyang Technological University, Singapore (NTU Singapore), Tan Tock Seng Hospital (TTSH) in Singapore, and the Massachusetts Institute of Technology (MIT) has developed a simple method of extracting tiny biological particles from a person's blood and use them as biomarkers to assess the health of their blood vessels.

27 Jul 2021

Novel microfluidic device used to manipulate major whey protein

After gaining world attention by 'unboiling' egg protein, Flinders University scientists have now used an Australian-made novel thin film microfluidic device to manipulate Beta-lactoglobulin (β-lactoglobulin), the major whey protein in cow's, sheep's and other mammals.

26 Jul 2021

Researchers identify an unexpected effect for already characterized active substances

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021

Scientists uncover the early assembly of gamma-secretase involved in plaque production

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease.

23 Jul 2021

New blood test could help predict the severity of COVID-19 symptoms

During the height of the pandemic, some hospitals were overwhelmed with patients seeking treatment for COVID-19.

22 Jul 2021

Finding most promising targets for pan-coronavirus drugs

Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever.

22 Jul 2021

Researchers use nanoparticles as heaters to manipulate the electrical activity of neurons

Nanomaterials have been used in a variety of emerging applications, such as in targeted pharmaceuticals or to bolster other materials and products such as sensors and energy harvesting and storage devices.

22 Jul 2021

Research focuses on ways to enhance gluten-free products

Gluten is a protein complex found in cereals such as wheat, rye and barley. It is responsible for the elastic texture of dough so that loaves and rolls can be baked into different shapes while remaining flexible and crusty. It also lengthens the shelf life of bread at room temperature, when associated with preservatives.

21 Jul 2021

Traditional Japanese dish may hold an answer to COVID-19

Natto, a fermented soybean dish often served for breakfast in Japan, originated at the turn of the last millennium but may hold an answer to a modern problem: COVID-19, according to a new study based on cell cultures.

21 Jul 2021

Virginia Tech's in-house development of novel SARS-CoV-2 test shows the power of academic labs

In the early days of the pandemic, scientists at Virginia Tech created a COVID-19 testing laboratory and novel test for the virus from scratch.

21 Jul 2021

New substance derived from Saussurea controversa exhibits osteoprotective properties

Metabolic bone diseases, including osteoporosis, when bones lose their mass and become so fragile that they could be damaged while sneezing or under little stress, are called the silent epidemic of the 21st century.

20 Jul 2021

DRI scientists awarded NIH grant to study the formation of dangerous compounds by e-cigarettes

Scientists with the Desert Research Institute Organic Analytical Laboratory in Reno, Nev., led by Andrey Khlystov, Ph.D., have been awarded a $1.5M grant from the National Institutes of Health (NIH) to study the formation of dangerous compounds by electronic cigarettes (e-cigarettes).

20 Jul 2021

Chemical modification in RNA molecules may offer protection against liver disease

A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells' protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver and can lead to advanced liver disease, according to a new study by UCLA researchers.

19 Jul 2021

Biochemistry

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

New review: How chemical reactions can be used to build computing systems

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Study paves the way to a new drug design concept

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

The Role of FT-NIR Spectroscopy in Edible Oils and Fats

Simple method to assess the risk of vascular inflammation for diabetes patients

Novel microfluidic device used to manipulate major whey protein

Researchers identify an unexpected effect for already characterized active substances

Scientists uncover the early assembly of gamma-secretase involved in plaque production

New blood test could help predict the severity of COVID-19 symptoms

Finding most promising targets for pan-coronavirus drugs

Researchers use nanoparticles as heaters to manipulate the electrical activity of neurons

Research focuses on ways to enhance gluten-free products

Traditional Japanese dish may hold an answer to COVID-19

Virginia Tech's in-house development of novel SARS-CoV-2 test shows the power of academic labs

New substance derived from Saussurea controversa exhibits osteoprotective properties

DRI scientists awarded NIH grant to study the formation of dangerous compounds by e-cigarettes

Chemical modification in RNA molecules may offer protection against liver disease

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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