Biochemistry

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Pharmacists discover active substances that block SARS-CoV-2 replication

A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key enzyme of the virus, the so-called main protease.

3 Mar 2021

New instrument could obtain VCD spectrum of dipeptides

Currently, the roles of free D-amino acids and D-amino acid residues in proteins are garnering extensive attention in biological fields such as molecular biology, physiology, microbiology, and pathophysiology.

3 Mar 2021

Coronavirus-like nanoparticles could serve as a positive control for COVID-19 tests

Rapid COVID-19 tests are on the rise to deliver results faster to more people, and scientists need an easy, foolproof way to know that these tests work correctly and the results can be trusted. Nanoparticles that pass detection as the novel coronavirus could be just the ticket.

2 Mar 2021

Scientists reprogram a common bacterium to make designer sugar-based drug

Envisioning an animal-free drug supply, scientists have -; for the first time -; reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.

2 Mar 2021

New 4D hydrogels may help develop tissues that closely resemble their natural counterparts

Tissue engineering has long-depended on geometrically static scaffolds seeded with cells in the lab to create new tissues and even organs.

2 Mar 2021

Scientists test the effect of natural product isolated from sea sponge on cancer cells

Scientists from Far Eastern Federal University together with Russian and German colleagues, continue studying antitumor compounds synthesized based on bioactive molecules isolated from a sea sponge.

1 Mar 2021

New, revolutionary theory for understanding brain and memory function

Research from the University of Kent has led to the development of the MeshCODE theory, a revolutionary new theory for understanding brain and memory function.

1 Mar 2021

Scientists develop a simple method to make drug precursor

Save your silver! It's better used for jewelry than as a catalyst for drugs. Rice University scientists have developed a greatly simplified method to make fluoroketones, precursors for drug design and manufacture that typically require a silver catalyst.

27 Feb 2021

Well-known spasmolytic drug can suppress inflammatory response in astrocytes

Biologists from RUDN University confirmed that a well-known spasmolytic drug called hymecromone can suppress the inflammatory response in astrocytes, important glial cells of the central nervous system.

26 Feb 2021

Special issue provides valuable summarization of risk assessment approaches for PFAS

Per- and polyfluoroalkyl substances (PFAS) are a class of man-made chemical compounds and a current, emerging concern to environmental health.

26 Feb 2021

KAUST researchers develop a safe, fast and cheap testing method to detect viruses

A safe, fast and cheap testing method that uses magnetic nanoparticles to detect viruses in both clinical and wastewater samples has been developed by KAUST researchers.

25 Feb 2021

Study reveals a potential target for stroke treatment in blood-brain barrier

The blood-brain barrier prevents immune cells from circulating freely in the brain, and the breakdown of its function is a major cause of post-stroke inflammation.

23 Feb 2021

Fooling the novel coronavirus with a fake handshake to inactivate the virus

Fool the novel coronavirus once and it can't cause infection of cells, new research suggests.

22 Feb 2021

Study provides better understanding of metabolic routes involved in regulating satiety

Results of the European study SATIN (SATiety INnovation) reveal a relation between certain metabolites in the blood and the satiety perceived after consuming food.

22 Feb 2021

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Monoclonal antibodies are part of the therapeutic arsenal for eliminating cancer cells. Some make use of the immune system to act and belong to a class of treatment called "immunotherapies." But how do these antibodies function within the tumor? And how can we hope to improve their efficacy?

22 Feb 2021

Researchers expand understanding of hop genome with implications for brewing industry

Oregon State University and U.S. Department of Agriculture researchers have significantly expanded the understanding of the hop genome, a development with important implications for the brewing industry and scientists who study the potential medical benefits of hops.

22 Feb 2021

New project seeks to adapt marine bioproducts into tasty vegan food ideas

Putting innovative Australian marine bioproducts into tasty vegan food ideas is the goal of a new project at the Centre for Marine Bioproducts Development, Flinders University.

22 Feb 2021

Study: Quantum mechanics plays a role in biological processes and causes mutations in DNA

Quantum biology is an emerging field of science, established in the 1920s, which looks at whether the subatomic world of quantum mechanics plays a role in living cells.

22 Feb 2021

Human monoclonal antibodies can act as a substitute for traditional antibiotics

In the course of a new and groundbreaking study, led by Dr, Natalia Freund and the doctoral candidate Avia Waston at the Sackler Medical Faculty, the research group succeeded in isolating monoclonal antibodies, which hindered the growth of tuberculosis germs in laboratory mice. The

22 Feb 2021

Researchers study how the methylation of proteins affects different mitochondrial processes

Disorders of the cells' energy supply can cause a number of serious diseases, but also seem to be connected to aging.

20 Feb 2021

Biochemistry

Pharmacists discover active substances that block SARS-CoV-2 replication

New instrument could obtain VCD spectrum of dipeptides

Coronavirus-like nanoparticles could serve as a positive control for COVID-19 tests

Scientists reprogram a common bacterium to make designer sugar-based drug

New 4D hydrogels may help develop tissues that closely resemble their natural counterparts

Scientists test the effect of natural product isolated from sea sponge on cancer cells

New, revolutionary theory for understanding brain and memory function

Scientists develop a simple method to make drug precursor

Well-known spasmolytic drug can suppress inflammatory response in astrocytes

Special issue provides valuable summarization of risk assessment approaches for PFAS

KAUST researchers develop a safe, fast and cheap testing method to detect viruses

Study reveals a potential target for stroke treatment in blood-brain barrier

Fooling the novel coronavirus with a fake handshake to inactivate the virus

Study provides better understanding of metabolic routes involved in regulating satiety

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Researchers expand understanding of hop genome with implications for brewing industry

New project seeks to adapt marine bioproducts into tasty vegan food ideas

Study: Quantum mechanics plays a role in biological processes and causes mutations in DNA

Human monoclonal antibodies can act as a substitute for traditional antibiotics

Researchers study how the methylation of proteins affects different mitochondrial processes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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