Biochemistry

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Research provides insight into protein structures that could treat Huntington’s disease

In Huntington's disease, a faulty protein aggregates in brain cells and eventually kills them. Such protein aggregates could, in principle, be prevented with a heat shock protein. However, it is not well known how these proteins interact with the Huntington's disease protein.

12 Feb 2021

New research aims to explore functions of bile acids in the gut stem cell niche

Examining gut health from a different angle, Flinders University’s Associate Professor Robyn Meech is looking at what can trigger colon cancer – and she believes bile acids may provide a significant piece of the puzzle.

12 Feb 2021

Portable suitcase lab for rapid detection of SARS-CoV-2

The PCR test is the most accurate tool to identify SARS-CoV-2. However, valid results are often available only after days.

12 Feb 2021

Scientists present new outlook on latest trends in peptide drug discovery and development

Currently there are more than 80 peptide drugs on the global market and about twice as many in clinical development.

10 Feb 2021

Scientists decipher the molecular blueprint for important receptor

In order for a drug to be effective at the right places in the body, it helps if scientists can predict as accurately as possible how the molecules of that drug will interact with human cells.

10 Feb 2021

Metabolomics and machine learning used to identify possible COVID-19 biomarkers

One of the many mysteries still surrounding COVID-19 is why some people experience only mild, flu-like symptoms, whereas others suffer life-threatening respiratory problems, vascular dysfunction and tissue damage.

10 Feb 2021

Researchers develop new weapon to fight against resistant bacteria

Every day, people die from simple infections even though they have been treated with antibiotics. This is because more and more bacteria have become resistant to the types of antibiotics that doctors can prescribe.

10 Feb 2021

Taking Advantage of Measuring Molecular Collisional Cross-Sections in Pharma

News-Medical talks to Mike Greig, Director of Pharma at Bruker, about why measuring collisional cross-sections is beneficial to developing new drugs.

From Bruker Life Sciences Mass Spectrometry 10 Feb 2021

Modified lipids target the body’s endocannabinoid system to regulate pain and inflammation

When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, researchers report.

10 Feb 2021

Researchers analyze how messenger substances influence individual decision-making

As indicated by other studies, different parts of the brain are responsible for different types of decisions.

10 Feb 2021

Nature Inspired Materials

An Interview with Dr. Lauren Zarzar, exploring how the natural world can serve as both inspiration and model for the invention of dynamic materials, to be presented at Pittcon 2021

From Pittcon 10 Feb 2021

Researchers create bone replicas using a hot nano-chisel

A holy grail for orthopedic research is a method for not only creating artificial bone tissue that precisely matches the real thing, but does so in such microscopic detail that it includes tiny structures potentially important for stem cell differentiation, which is key to bone regeneration.

9 Feb 2021

Study sheds light on dangerous nanomaterials lurking in our consumer products

Our consumer products, such as food, cosmetics and clothes, might be filled with nanomaterials - unbeknownst to us.

9 Feb 2021

New wearable sensor uses nanomaterials technology to detect illegal drugs in sweat

Researchers in South Korea have successfully developed a wearable sensor that can detect illegal drugs in sweat by using nanomaterials technology that amplify the optical signal of narcotics to a flexible, body-worn material.

8 Feb 2021

Novel plastic film can deactivate 99.99% of the new coronavirus in 15 minutes

A consortium comprised by companies Braskem, AplFilm and Nanox and the UFSCar (Brazil) and Jaume I of Castellón (Spain) universities have released a plastic film capable of deactivating 99.99% of the new coronavirus in 15 minutes.

8 Feb 2021

Discovery may reduce the environmental impact of chemical manufacturing

Chemical manufacturers frequently use toxic solvents such as alcohols and benzene to make products like pharmaceuticals and plastics.

5 Feb 2021

Research could pave way for injectable gels that release drugs over time

Gels are formed by mixing polymers into fluids to create gooey substances useful for everything from holding hair in place to enabling contact lenses to float over the eye.

4 Feb 2021

Experimental vaccine diminishes fatal respiratory effects of synthetic opioids

As the opioid epidemic raged on with an even greater force during COVID-19, the Scripps Research laboratory of chemist Kim Janda, PhD, has been working on new therapeutic interventions that may be able to prevent the bulk of deaths from opioid overdose.

4 Feb 2021

Sulforaphane prolongs lifespan and healthspan of C. elegans through insulin/IGF-1 signaling

Aging-US published "Sulforaphane promotes C. elegans longevity and healthspan via DAF- 16/DAF-2 insulin/IGF-1 signaling" which reported that the broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and longevity are unclear.

4 Feb 2021

Research could open the door to next-generation of cancer drugs that work better

Some of the most commonly used drugs for treating hereditary breast and ovarian cancers may not work the way we thought they did, according to new University of Colorado Boulder research.

3 Feb 2021