Biochemistry

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Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer of lymphocytes, and a large proportion of patients are either unresponsive or develop resistance towards R-CHOP—the standard treatment regimen.

8 Mar 2021

A small sensor can be used for rapid detection of RNA and DNA

In less than a second, a small sensor used in brain chemistry research can detect the key molecules that provide the genetic instructions for life, RNA, and DNA, a new study from American University shows

5 Mar 2021

New COVID-19 variants can evade antibodies that work against original form of the virus

New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic.

5 Mar 2021

Study demonstrates the impact of 'reverse antibiotic' on gram-negative bacteria

Scientists from Skoltech and MSU have investigated antibiotic nybomycin that could prove effective against bacteria resistant to other antibiotics. Their research was published in the journal Antimicrobial Agents and Chemotherapy.

5 Mar 2021

Insight into how plants sense zinc could help cultivate more nutritious crops

Over 2 billion people worldwide are malnourished due to zinc deficiency. Led by the University of Copenhagen, an international team of researchers has discovered how plants sense zinc and use this knowledge to enhance plant zinc uptake, leading to an increase in seed zinc content by 50 percent.

5 Mar 2021

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Pancreatitis drug Camostat inhibits new SARS-CoV-2 activators identified in the upper respiratory tract. There are no therapeutics available that have been developed for COVID-19 treatment.

5 Mar 2021

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

A compound isolated from a fungus growing on the roots of a flowering plant in Morocco shows promise as a powerful opponent of aggressive triple negative breast cancer, scientists say.

4 Mar 2021

Structural insights into glycine transporter open new avenues to find effective psychiatric drugs

Glycine can stimulate or inhibit neurons in the brain, thereby controlling complex functions. Unraveling the three-dimensional structure of the glycine transporter, researchers have now come a big step closer to understanding the regulation of glycine in the brain.

4 Mar 2021

The Role of D-Amino Acids in Humans

In this interview, Dr. Daniel Armstrong from the University of Texas at Arlington talks to News-Medical Life Sciences about his upcoming Pittcon presentation.

From Pittcon 4 Mar 2021

Bayreuth researchers develop a rapid test to detect quality and authenticity of olive oil

Extra virgin olive oil is extracted from cold-pressed, high-quality olives and is one of the most popular foods in Europe. However, inferior counterfeits are coming onto the market in increasing number.

3 Mar 2021

Pharmacists discover active substances that block SARS-CoV-2 replication

A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key enzyme of the virus, the so-called main protease.

3 Mar 2021

New instrument could obtain VCD spectrum of dipeptides

Currently, the roles of free D-amino acids and D-amino acid residues in proteins are garnering extensive attention in biological fields such as molecular biology, physiology, microbiology, and pathophysiology.

3 Mar 2021

Coronavirus-like nanoparticles could serve as a positive control for COVID-19 tests

Rapid COVID-19 tests are on the rise to deliver results faster to more people, and scientists need an easy, foolproof way to know that these tests work correctly and the results can be trusted. Nanoparticles that pass detection as the novel coronavirus could be just the ticket.

2 Mar 2021

Scientists reprogram a common bacterium to make designer sugar-based drug

Envisioning an animal-free drug supply, scientists have - for the first time - reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.

2 Mar 2021

New 4D hydrogels may help develop tissues that closely resemble their natural counterparts

Tissue engineering has long-depended on geometrically static scaffolds seeded with cells in the lab to create new tissues and even organs.

2 Mar 2021

Scientists test the effect of natural product isolated from sea sponge on cancer cells

Scientists from Far Eastern Federal University together with Russian and German colleagues, continue studying antitumor compounds synthesized based on bioactive molecules isolated from a sea sponge.

1 Mar 2021

New, revolutionary theory for understanding brain and memory function

Research from the University of Kent has led to the development of the MeshCODE theory, a revolutionary new theory for understanding brain and memory function.

1 Mar 2021

Scientists develop a simple method to make drug precursor

Save your silver! It's better used for jewelry than as a catalyst for drugs. Rice University scientists have developed a greatly simplified method to make fluoroketones, precursors for drug design and manufacture that typically require a silver catalyst.

27 Feb 2021

Well-known spasmolytic drug can suppress inflammatory response in astrocytes

Biologists from RUDN University confirmed that a well-known spasmolytic drug called hymecromone can suppress the inflammatory response in astrocytes, important glial cells of the central nervous system.

26 Feb 2021

Special issue provides valuable summarization of risk assessment approaches for PFAS

Per- and polyfluoroalkyl substances (PFAS) are a class of man-made chemical compounds and a current, emerging concern to environmental health.

26 Feb 2021

Biochemistry

Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

A small sensor can be used for rapid detection of RNA and DNA

New COVID-19 variants can evade antibodies that work against original form of the virus

Study demonstrates the impact of 'reverse antibiotic' on gram-negative bacteria

Insight into how plants sense zinc could help cultivate more nutritious crops

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

Structural insights into glycine transporter open new avenues to find effective psychiatric drugs

The Role of D-Amino Acids in Humans

Bayreuth researchers develop a rapid test to detect quality and authenticity of olive oil

Pharmacists discover active substances that block SARS-CoV-2 replication

New instrument could obtain VCD spectrum of dipeptides

Coronavirus-like nanoparticles could serve as a positive control for COVID-19 tests

Scientists reprogram a common bacterium to make designer sugar-based drug

New 4D hydrogels may help develop tissues that closely resemble their natural counterparts

Scientists test the effect of natural product isolated from sea sponge on cancer cells

New, revolutionary theory for understanding brain and memory function

Scientists develop a simple method to make drug precursor

Well-known spasmolytic drug can suppress inflammatory response in astrocytes

Special issue provides valuable summarization of risk assessment approaches for PFAS

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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