Cell Biology

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Tiny sea creature offers new clues to regeneration and aging

Insights into healing and aging were discovered by National Institutes of Health researchers and their collaborators, who studied how a tiny sea creature regenerates an entire new body from only its mouth.

30 Jun 2023

Novel engineered approach makes protein aggregates amenable to spatial manipulations in cells

Protein aggregates accumulate during aging and are linked to neurodegenerative diseases like Alzheimer's, Parkinson's or Huntington's disease.

30 Jun 2023

Using genetics to gain better insights into human behavior

Humans contain multitudes. Each person on the planet contains enough DNA to stretch to Pluto – several times.

30 Jun 2023

Scientists visualize dynamic motion of gene regions on chromosomes

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion.

29 Jun 2023

New method can track the complete activity of proteins in living cells

The genetic plans within our DNA come to functional fruition through proteins, which underlie our bodies' structure and activity.

29 Jun 2023

Three-dimensional epithelial lip area model developed for cosmetics research

KOSÉ Corporation (Headquarters: Chuo-ku, Tokyo; President: Kazutoshi Kobayashi) has developed in collaborative research with Professor Kenji Izumi and his colleagues at Niigata University Graduate School of Medical and Dental Sciences (Faculty of Dentistry) a three-dimensional epithelial model that reproduces the human lip area from the oral mucosa to the lips and surrounding skin, using cell culture.

29 Jun 2023

Scientists use designer tubulins to crack the tubulin code

Tubulin is a protein that plays a crucial role in the structure and function of cells. It is the main component of microtubules, which are long, hollow fibers that provide structural support, help the cell divide, give it its shape, and act as tracks for moving molecular cargo around inside the cell.

29 Jun 2023

Duke researchers expand functionality of CRISPR gene editing

CRISPR gene editing is a breakthrough that has been used to treat diseases such as sickle cell anemia, leukemia and genetic disorders, but it has challenges that limit its broad utility.

29 Jun 2023

New atlas offers a way to identify the deep mechanisms of cancer

An atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifying the deep mechanisms of cancer, according to researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center.

29 Jun 2023

AI may hold the key to a sharper and more precise DNA scissor technology

Artificial Intelligence may be the key to more precise and effective gene therapy treatments. A new study from Aarhus University has found, that applying AI predictions of protein structures enhances the DNA scissor technology CRISPR, by making the cuts in a patient's DNA more precise.

29 Jun 2023

Researcher from Wageningen University wins Green CellDrop Giveaway

DeNovix Inc. is pleased to announce the winner of the Green CellDrop Automated Cell Counter Giveaway: Michiel Schrijen from Wageningen University, Netherlands! Selected at random from thousands of entries from scientists worldwide, the CellDrop will be housed in the Biosystematics Group at the university.

From DeNovix Inc. 29 Jun 2023

First programmable RNA-guided system found in eukaryotes

A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in eukaryotes - organisms that include fungi, plants, and animals.

28 Jun 2023

World's largest map of breast tissue provides an unprecedented understanding of mammary biology

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

28 Jun 2023

Single-cell transcriptomic analysis reveals specific cellular signatures for kidney transplant rejection

Imagine a day when a urine test could inform a doctor precisely why a kidney transplant patient was experiencing organ rejection and suggest the best medication for specifically addressing the problem.

28 Jun 2023

Researchers develop light-controlled drug delivery system using liposomes

Artificial lipid bilayer vesicle liposomes, also called proteoliposomes, are specialized systems capable of incorporating various molecules, such as chemicals and drugs.

28 Jun 2023

New method could revolutionize the delivery of antioxidants to stem cells

As we age, our bodies change and degenerate over time in a process called senescence. Stem cells, which have the unique ability to change into other cell types, also experience senescence, which presents an issue when trying to maintain cell cultures for therapeutic use.

27 Jun 2023

Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

Single-cell profiling reveals immune cell marker and regulator of anti-tumor immunity

B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown.

23 Jun 2023

Eliminating cancer cell repopulation may be the key to curing cancer

A new research perspective was published in Oncoscience (Volume 10) on June 1, 2023, entitled, "Cancer cell repopulation after therapy: which is the mechanism?"

23 Jun 2023

3D models of ovarian cancer reveal how cell’s location can affect tumor biology

Using 3-D models of ovarian cancer tumors, scientists found differences in gene activity based on where a cell is in a tumor, demonstrating how a cell's location and environment in a cancerous tumor can strongly influence which genes are active and the cell's role in the cancer's biology.

23 Jun 2023