Cell Biology

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Researchers develop a virtual molecular library of thousands of 'command sentences' for cells

Using new machine learning techniques, researchers at UC San Francisco (UCSF), in collaboration with a team at IBM Research, have developed a virtual molecular library of thousands of "command sentences" for cells, based on combinations of "words" that guided engineered immune cells to seek out and tirelessly kill cancer cells.

8 Dec 2022

Study looks at the possibility of promoting hair cell regeneration using cell reprograming

About 430 million people around the world experience disabling hearing loss. In the United States, approximately 37.5 million adults report some trouble hearing. Hearing loss can happen when any part of the ear or the nerves that carry information on sounds to the brain do not work in the usual way.

8 Dec 2022

New spatial cell atlas of the developing human lung identifies 144 cell states

The developing human lung has been mapped in unprecedented detail, identifying 144 cell states in the early stages of life, and uncovering new links between developmental cells and lung cancer.

8 Dec 2022

Research explores cell receptors for bat viruses to understand emergence of zoonotic diseases

New research shows that the closest bat virus relatives of the human Middle-East Respiratory Syndrome (MERS) coronavirus efficiently bind to bat ACE2 receptors as an entry point into these cells.

8 Dec 2022

Whole genome sequencing helps construct the first blood virological profile of Chinese population

Whole genome sequencing technology can discover various known or unspecified viral sequences contained in human blood, which can provide an important database for viral infection prevention, vaccine development, viral genomic and epidemiological research.

7 Dec 2022

URI entomologist receives NIH grant to study ecological factors driving the evolution of Lyme disease bacteria in ticks

University of Rhode Island entomologist Jannelle Couret is tipping the way we understand the bacteria that causes Lyme disease.

7 Dec 2022

Salk researchers shed new light on specific mechanisms that activate oncogenes

Cancer, caused by abnormal overgrowth of cells, is the second-leading cause of death in the world. Researchers from the Salk Institute have zeroed in on specific mechanisms that activate oncogenes, which are altered genes that can cause normal cells to become cancer cells.

7 Dec 2022

Shenandoah Biotechnology introduces expanded range of CTGrade recombinant proteins manufactured following cGMP practices

Shenandoah Biotechnology Inc., a FUJIFILM Irvine Scientific company and leading manufacturer of recombinant proteins, today announced it has expanded its CTGrade portfolio of cytokines and growth factors for cell and gene therapies manufactured following cGMP guidelines.

From FUJIFILM Irvine Scientific 7 Dec 2022

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Growing human body parts in the lab is a common trope of horror movies and sci-fi books. But growing miniature organ-like tissues in the lab is already within our reach.

6 Dec 2022

New study details the neuronal response to excessive aged-related iron accumulation

Iron (Fe) accumulates in the brain cortex with aging. A plethora of studies indicate that progressive iron accumulation in the substantia nigra (SN) in the aged human brain is a major risk factor for Parkinson's disease (PD) and other neurodegenerative diseases, but not everyone.

6 Dec 2022

Research explores how alignment of endothelial cells plays a role in cancer metastasis

Preventing metastasis – the development of cancer cells beyond their original location – remains one of the major goals of current cancer research.

6 Dec 2022

Pre-Plated Assay Solutions That Can Help Accelerate Biotech

In this interview, we speak with University of Warwick spin-out Cryologyx about their innovative new technology that hopes to revolutionize cell-based assays for researchers across life sciences and drug discovery.

From Cryologyx Ltd 6 Dec 2022

Researchers discover new mechanism that enables cancer cells to move throughout the body

An international team of researchers has uncovered a new mechanism that enables cancer cells to move throughout the body, providing a potential new target to stop metastasis, which is responsible for 90 per cent of cancer deaths.

5 Dec 2022

Study predicts persistent cross-species SARS-CoV-2 variant infectivity

Scientists believe bats first transmitted SARS-CoV-2 to humans in December 2019, and while the virus has since evolved into several variants such as delta and omicron, a new study indicates the virus is still highly transmissible between mammals.

5 Dec 2022

New insights into how the circadian clock influences T cell responses to vaccination

Research by RCSI University of Medicine and Health Sciences has provided new insights into the mechanism behind how our circadian 24-hour body clock influences our immune response to vaccines, depending on the time of day.

5 Dec 2022

Sharp increase in B cell population can prevent intestinal healing

B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, preventing the tissue from healing.

2 Dec 2022

New Collaborative Research Center investigates how Treg cells influence immunological and tissue-specific diseases

The German Research Foundation (DFG) has approved the establishment and funding of the Collaborative Research Center/Transregio (CRC/TRR) 355 "Heterogeneity and functional specialization of regulatory T cells in distinct microenvironments".

2 Dec 2022

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

Our kidney filters 180 liters of blood every day and retains nutrients through a process called 'endocytosis' and through active transport in the kidney cells.

2 Dec 2022

Collaborative work unravels hidden molecular secrets of age-related diseases

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, and the University of Copenhagen announced today the release of the first batch of results from the collaborative work directed to perform multi-omics-based analyses in the context of age-related diseases using an AI-driven target and drug discovery pipeline.

2 Dec 2022

Scaling up the production of customized immune cells for drug development and testing

To prevent testing on animals and create even more precise ways of testing therapeutics, the pharmaceutical industry is increasingly turning to human immune cells.

1 Dec 2022

Cell Biology

Researchers develop a virtual molecular library of thousands of 'command sentences' for cells

Study looks at the possibility of promoting hair cell regeneration using cell reprograming

New spatial cell atlas of the developing human lung identifies 144 cell states

Research explores cell receptors for bat viruses to understand emergence of zoonotic diseases

Whole genome sequencing helps construct the first blood virological profile of Chinese population

URI entomologist receives NIH grant to study ecological factors driving the evolution of Lyme disease bacteria in ticks

Salk researchers shed new light on specific mechanisms that activate oncogenes

Shenandoah Biotechnology introduces expanded range of CTGrade recombinant proteins manufactured following cGMP practices

New approach enables robust intestinal mini-organs to be grown more easily in the lab

New study details the neuronal response to excessive aged-related iron accumulation

Research explores how alignment of endothelial cells plays a role in cancer metastasis

Pre-Plated Assay Solutions That Can Help Accelerate Biotech

Researchers discover new mechanism that enables cancer cells to move throughout the body

Study predicts persistent cross-species SARS-CoV-2 variant infectivity

New insights into how the circadian clock influences T cell responses to vaccination

Sharp increase in B cell population can prevent intestinal healing

New Collaborative Research Center investigates how Treg cells influence immunological and tissue-specific diseases

Multiomics analysis of kidney metabolism reveals a gatekeeper for viral infections

Collaborative work unravels hidden molecular secrets of age-related diseases

Scaling up the production of customized immune cells for drug development and testing

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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