Cell Biology

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Sphere Fluidics expands Cyto-Mine capabilities to meet cGMP requirements for drug manufacture workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced updates to its flagship platform, Cyto-Mine®, enabling it to be compliant with current Good Manufacturing Practice (cGMP) regulations enforced by the US FDA.

From Fluidic Sciences and Sphere Bio 6 Jul 2023

Using a vaccine to boost the response of engineered T cells

Engineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. However, it hasn't worked as well for solid tumors.

5 Jul 2023

Study shows how glutamine can help or hinder cancer-killing activity

Scientists at St. Jude Children's Research Hospital found immune and tumor cells compete over glutamine, a major nutrient in their local environment, with significant implications for anti-cancer activity.

5 Jul 2023

Researchers discover a molecular switch that regulates lipid metabolism in cells

Our body's fat metabolism plays a vital role in energy production in our body. A research team at the University of Basel, Switzerland, has discovered a molecular switch that regulates lipid metabolism in our cells.

3 Jul 2023

Research reveals how cells carry out the controlled release of mucins and insulin

Researchers from the Centre for Genomic Regulation (CRG) in Barcelona have published a study in the journal Nature Communications that reveals how cells carry out the controlled release of mucins and insulin, two crucial proteins for human health.

3 Jul 2023

Tiny sea creature offers new clues to regeneration and aging

Insights into healing and aging were discovered by National Institutes of Health researchers and their collaborators, who studied how a tiny sea creature regenerates an entire new body from only its mouth.

30 Jun 2023

Novel engineered approach makes protein aggregates amenable to spatial manipulations in cells

Protein aggregates accumulate during aging and are linked to neurodegenerative diseases like Alzheimer's, Parkinson's or Huntington's disease.

30 Jun 2023

Using genetics to gain better insights into human behavior

Humans contain multitudes. Each person on the planet contains enough DNA to stretch to Pluto – several times.

30 Jun 2023

Scientists visualize dynamic motion of gene regions on chromosomes

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion.

29 Jun 2023

New method can track the complete activity of proteins in living cells

The genetic plans within our DNA come to functional fruition through proteins, which underlie our bodies' structure and activity.

29 Jun 2023

Three-dimensional epithelial lip area model developed for cosmetics research

KOSÉ Corporation (Headquarters: Chuo-ku, Tokyo; President: Kazutoshi Kobayashi) has developed in collaborative research with Professor Kenji Izumi and his colleagues at Niigata University Graduate School of Medical and Dental Sciences (Faculty of Dentistry) a three-dimensional epithelial model that reproduces the human lip area from the oral mucosa to the lips and surrounding skin, using cell culture.

29 Jun 2023

Scientists use designer tubulins to crack the tubulin code

Tubulin is a protein that plays a crucial role in the structure and function of cells. It is the main component of microtubules, which are long, hollow fibers that provide structural support, help the cell divide, give it its shape, and act as tracks for moving molecular cargo around inside the cell.

29 Jun 2023

Duke researchers expand functionality of CRISPR gene editing

CRISPR gene editing is a breakthrough that has been used to treat diseases such as sickle cell anemia, leukemia and genetic disorders, but it has challenges that limit its broad utility.

29 Jun 2023

New atlas offers a way to identify the deep mechanisms of cancer

An atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifying the deep mechanisms of cancer, according to researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center.

29 Jun 2023

AI may hold the key to a sharper and more precise DNA scissor technology

Artificial Intelligence may be the key to more precise and effective gene therapy treatments. A new study from Aarhus University has found, that applying AI predictions of protein structures enhances the DNA scissor technology CRISPR, by making the cuts in a patient's DNA more precise.

29 Jun 2023

Researcher from Wageningen University wins Green CellDrop Giveaway

DeNovix Inc. is pleased to announce the winner of the Green CellDrop Automated Cell Counter Giveaway: Michiel Schrijen from Wageningen University, Netherlands! Selected at random from thousands of entries from scientists worldwide, the CellDrop will be housed in the Biosystematics Group at the university.

From DeNovix Inc. 29 Jun 2023

First programmable RNA-guided system found in eukaryotes

A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in eukaryotes - organisms that include fungi, plants, and animals.

28 Jun 2023

World's largest map of breast tissue provides an unprecedented understanding of mammary biology

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

28 Jun 2023

Single-cell transcriptomic analysis reveals specific cellular signatures for kidney transplant rejection

Imagine a day when a urine test could inform a doctor precisely why a kidney transplant patient was experiencing organ rejection and suggest the best medication for specifically addressing the problem.

28 Jun 2023

Researchers develop light-controlled drug delivery system using liposomes

Artificial lipid bilayer vesicle liposomes, also called proteoliposomes, are specialized systems capable of incorporating various molecules, such as chemicals and drugs.

28 Jun 2023