Cell Biology

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Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies."

29 Dec 2022

Unraveling the biology of senescent cells and healthy aging

Multiple researchers at the Jackson Laboratory are taking part in an ambitious research program spanning several top research institutions to study senescent cells.

29 Dec 2022

Researchers unravel how cells use their sense of touch to make decisions during embryogenesis

A research team at the Cluster of Excellence Physics of Life of TU Dresden and the University of California, Santa Barbara, reveals how cells sense their mechanical environment as they build tissues during embryogenesis.

28 Dec 2022

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine.

28 Dec 2022

New mathematical model for the motion of bacteria

Biofilms form when microorganisms such as certain types of bacteria adhere to the surface of objects in a moist environment and begin to reproduce resulting in the excretion of a slimy glue-like substance.

28 Dec 2022

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential.

28 Dec 2022

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues.

28 Dec 2022

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

A Japanese research group has become the first to reveal that the checkerboard-like arrangement of cells in the inner ear's organ of Corti is vital for hearing.

27 Dec 2022

Study reveals why some germinal centers persist for months rather than weeks

If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities.

23 Dec 2022

High ammonia levels lead to fewer T cells and immunotherapy resistance in colorectal cancer

High levels of ammonia in tumors lead to fewer T cells and immunotherapy resistance in mouse models of colorectal cancer, new findings from the University of Michigan Rogel Cancer Center revealed.

23 Dec 2022

New technology achieves 99.7% purity in sorting target cells in real-time

Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences have proposed a new technology, called optical tweezer-assisted pool-screening and single-cell isolation (OPSI) system, which achieves 99.7% purity of sorting target cells, with all done in real-time.

23 Dec 2022

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies.

22 Dec 2022

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

In order to treat patients with diabetes in the best possible way it is necessary to understand the disease mechanism. MODY type 3 (MODY3) is a monogenic hereditary form of diabetes, that is caused by a genetic defect in the HNF1A gene.

22 Dec 2022

Specialized MRI sensor can detect light deep within tissues

Using a specialized MRI sensor, MIT researchers have shown that they can detect light deep within tissues such as the brain.

22 Dec 2022

Simple laser irradiation speeds up the detection of very small amounts of proteins

Protein detection based on antigen–antibody reaction is vital in early diagnosis of a wide range of diseases. How to effectively detect proteins, however, has frequently bedeviled researchers.

22 Dec 2022

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases.

22 Dec 2022

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome - a rare genetic, neurocognitive disorder.

22 Dec 2022

Research serves as a platform to identify therapeutic drugs for schizophrenia

Inflammation and overactivation of the immune system in the brain can cause loss of synapses and the death of neurons, leading to neurodegenerative and psychiatric diseases.

22 Dec 2022

3D neutron tomography reveals water diffusion across the bone material

What keeps bones able to remodel themselves and stay healthy? A team from Charité Berlin has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load.

22 Dec 2022

Researchers unravel how one of the crucial early steps on the path of life could have happened

One-hundred fifty years ago, Charles Darwin speculated that life likely originated in a warm little pond. There, Darwin supposed, chemical reactions and the odd lightning strike might have led to chains of amino acids that, over time, became more and more complex until the beginnings of life emerged.

21 Dec 2022

Cell Biology

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

Unraveling the biology of senescent cells and healthy aging

Researchers unravel how cells use their sense of touch to make decisions during embryogenesis

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

New mathematical model for the motion of bacteria

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

Study reveals why some germinal centers persist for months rather than weeks

High ammonia levels lead to fewer T cells and immunotherapy resistance in colorectal cancer

New technology achieves 99.7% purity in sorting target cells in real-time

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

Specialized MRI sensor can detect light deep within tissues

Simple laser irradiation speeds up the detection of very small amounts of proteins

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

Research serves as a platform to identify therapeutic drugs for schizophrenia

3D neutron tomography reveals water diffusion across the bone material

Researchers unravel how one of the crucial early steps on the path of life could have happened

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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