Cell Biology

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Primordial germ cell-like cells generated from rat stem cells enable the birth of normal offspring

Primordial germ cell-like cells (PGCLCs), generated in vitro from the stem cells of rats, undergo gametogenesis in vivo and yield normal rat offspring, a new study demonstrates.

7 Apr 2022

Cytoskeletal proteins work synergistically in the cell cortex to form intracellular networks

Investigators have discovered that two cytoskeletal proteins which were previously thought to function independently actually interact and form cytoskeletal networks within the cell surface, according to findings published in Proceedings of the National Academy of Sciences.

7 Apr 2022

Researchers design RNA molecules for delivering therapies directly to beta cells

Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 diabetes.

7 Apr 2022

New platform for studying how the immune system responds to hepatitis C

A vaccine for hepatitis C has eluded scientists for more than 30 years, for several reasons. For one, the virus that causes the disease comes in many genetic forms, complicating the creation of a widely effective vaccine.

6 Apr 2022

Curcumin released from magnetic hydrogels promotes the secretion of vascular endothelial growth factor

A finding by UC Riverside bioengineers could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients. The results are published in ACS Applied Materials and Interfaces.

6 Apr 2022

Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Cell Guidance Systems and Manchester BIOGEL collaborate to launch PODS-PeptiGels for 3D cell culture

Cell Guidance Systems Ltd today announced a collaboration to launch PODS®-PeptiGels®.

From Cell Guidance Systems 5 Apr 2022

Study reveals how pancreatic tumors program macrophages to construct fibrotic barriers

In the presence of pancreatic tumors, certain immune cells break down structural proteins into molecules that trigger the building of dense tissue, a known barrier to therapy, a new study finds.

4 Apr 2022

Powerhouse-pruning protein may also help make energy rapidly available for growing new blood vessels

A protein that helps keep our cell powerhouses working at a premium appears to also help make energy rapidly available when it's time to make new blood vessels.

4 Apr 2022

Key protein could be a novel target for treatment of patients with B cell signaling deficiencies

The rules to the kids' game "red light, green light" are easy to follow: red always means stop, and green always means go. But now, researchers from Japan have found that a key protein involved in B cell signaling acts as both a red light to signaling in healthy cells and a green light to signaling in immune-deficient cells.

4 Apr 2022

Phenolic extract from wild blueberries may improve wound healing

Treating wounds with an extract taken from wild blueberries may improve healing, according to a new study.

2 Apr 2022

Research illuminates why immune disorders affect only one of two identical twins

Scientists have long queried the causes of immune disorders in only one of two identical twins with identical genes. New research from the Wellcome Sanger Institute, the Josep Carreras Leukaemia Research Institute in Spain and their collaborators, has found the answer lies in both alterations in immune cell-cell communication and the epigenome, the host of biological processes that regulate how our genes function.

1 Apr 2022

Yale researchers identify accelerated genetic aging in breast tissue adjacent to tumors

An analysis by Yale Cancer Center researchers identified accelerated genetic aging in breast tissue adjacent to breast cancer tumors.

31 Mar 2022

Virginia Tech researcher awarded $1.9 million grant to study about mitophagy

Most of us remember enough biology to recall that mitochondria are known as "the powerhouse of the cell." Even that audacious term may downplay the importance of mitochondria and what happens when mitochondria go bad.

31 Mar 2022

COMBINEDBrain Biorepository: A comprehensive approach to speed research for rare diseases

COMBINEDBrain puts advocacy groups in the driver's seat in the race to cure rare neurodevelopmental diseases. Patient advocacy foundations representing more than thirty rare genetic neurodevelopmental disorders join forces as part of COMBINEDBrain to make it faster to do research on their disorders.

30 Mar 2022

Scientists create a biobank of 87 triple-negative breast cancer organoids

It's the cancer version of "mini me." Cold Spring Harbor Laboratory (CSHL) Professor David Spector, among others, has developed organoids, which are miniature, three-dimensional copies of cancers. Organoids can be derived from cancer or healthy cells.

30 Mar 2022

Cell Biology

Primordial germ cell-like cells generated from rat stem cells enable the birth of normal offspring

Cytoskeletal proteins work synergistically in the cell cortex to form intracellular networks

Researchers design RNA molecules for delivering therapies directly to beta cells

New platform for studying how the immune system responds to hepatitis C

Curcumin released from magnetic hydrogels promotes the secretion of vascular endothelial growth factor

Phenotypic changes in monocytes from COVID-19 patients

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Cell Guidance Systems and Manchester BIOGEL collaborate to launch PODS-PeptiGels for 3D cell culture

Study reveals how pancreatic tumors program macrophages to construct fibrotic barriers

Powerhouse-pruning protein may also help make energy rapidly available for growing new blood vessels

Key protein could be a novel target for treatment of patients with B cell signaling deficiencies

Phenolic extract from wild blueberries may improve wound healing

Research illuminates why immune disorders affect only one of two identical twins

Yale researchers identify accelerated genetic aging in breast tissue adjacent to tumors

Virginia Tech researcher awarded $1.9 million grant to study about mitophagy

COMBINEDBrain Biorepository: A comprehensive approach to speed research for rare diseases

Scientists create a biobank of 87 triple-negative breast cancer organoids

Bruker introduces Ultima Investigator Plus — Multiphoton microscope for tissue imaging

New tissue-clearing method could speed the study of many disease-related biological processes

Researchers discover a four-protein complex that may play key role in generating ribosomes

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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