Cell Biology

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Research shows re-formation of synaptic connectivity in dissociated retinal organoids

Retinal cells grown from stem cells can reach out and connect with neighbors, according to a new study, completing a "handshake" that may show the cells are ready for trials in humans with degenerative eye disorders.

4 Jan 2023

New type of CRISPR gene scissors discovered

Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens.

4 Jan 2023

Researchers develop new tool to isolate and analyze rare astrocyte regulators

Rare cell types can have an undue influence on human health. Previous research has suggested that a subset of astrocytes - star-shaped cells in the brain and spinal cord - may be responsible for multiple sclerosis (MS), a disease in which the immune system attacks the covering that protects nerves.

4 Jan 2023

Synthetic tissue repairs injuries and restores normal erectile function in pig model

Scientists have developed a synthetic tissue that repairs injuries and restores normal erectile function in a pig model, in a study publishing January 4 in the journal Matter.

4 Jan 2023

Antibiotic perseverance increases the risk of antibiotic resistance development

Bacterial perseverance is a new phenomenon that helps explain how bacteria adapt to survive antibiotic treatments.

4 Jan 2023

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

A clinical research team from the Department of Paediatrics and Adolescent Medicine and the Department of Obstetrics and Gynaecology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) leads the discovery of applying amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management.

4 Jan 2023

Physical activity inhibits the production of insulin

When a fruit fly starts walking or flying, its insulin-producing cells are immediately inhibited. This could be one explanation for why exercise promotes health.

4 Jan 2023

Researchers discover new cellular component with importance for the sense of smell

Researchers at Umeå University have discovered a previously unknown cellular component, an organelle, inside neurons that we use to perceive smell.

4 Jan 2023

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry.

3 Jan 2023

Salk scientists show how a microprotein can increase appetite in mice

Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that they have an important role in metabolism.

3 Jan 2023

Innovations in expansion microscopy allow unprecedented view of the interior of cells

Unprecedented views of the interior of cells and other nanoscale structures are now possible thanks to innovations in expansion microscopy.

2 Jan 2023

Researchers use engineered proteins to record histories of cellular events

As cells perform their everyday functions, they turn on a variety of genes and cellular pathways. MIT engineers have now coaxed cells to inscribe the history of these events in a long protein chain that can be imaged using a light microscope.

2 Jan 2023

New method records gene activity patterns and presence of proteins across tissues

A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center.

2 Jan 2023

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Researchers at UCSF have developed a novel, potentially life-saving approach that may prevent antibodies from triggering immune rejection of engineered therapeutic and transplant cells.

2 Jan 2023

Novel experimental approach slows physical decline and extends the lives of roundworms

Scientists in aging research today report a novel experimental approach that slowed the rate of physical decline and lengthened the lives of roundworms commonly used in biological studies, C. elgans.

30 Dec 2022

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife."

30 Dec 2022

Cell Biology

Research shows re-formation of synaptic connectivity in dissociated retinal organoids

New type of CRISPR gene scissors discovered

Researchers develop new tool to isolate and analyze rare astrocyte regulators

Synthetic tissue repairs injuries and restores normal erectile function in pig model

Antibiotic perseverance increases the risk of antibiotic resistance development

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

Physical activity inhibits the production of insulin

Researchers discover new cellular component with importance for the sense of smell

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Salk scientists show how a microprotein can increase appetite in mice

Innovations in expansion microscopy allow unprecedented view of the interior of cells

Researchers use engineered proteins to record histories of cellular events

New method records gene activity patterns and presence of proteins across tissues

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Novel experimental approach slows physical decline and extends the lives of roundworms

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

New insights on the circadian clock of Drosophila melanogaster

Study reveals novel role of PPARγ acetylation in macrophages in impairing adipose tissue function

New insights into how working memory information may be held in mind

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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