Cell Biology

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'Cellular glue' opens the door to building tissues and organs

Researchers at UC San Francisco have engineered molecules that act like "cellular glue," allowing them to direct in precise fashion how cells bond with each other.

13 Dec 2022

Report makes recommendations clarifying the ethics and oversight of chimeric research

A new report on the ethics of crossing species boundaries by inserting human cells into nonhuman animals – research surrounded by debate – makes recommendations clarifying the ethical issues and calling for improved oversight of this work.

13 Dec 2022

Nanomaterial can indirectly affect the immune system via the gut microbiome, study shows

The nanomaterial graphene oxide - which is used in everything from electronics to sensors for biomolecules - can indirectly affect the immune system via the gut microbiome, as shown in a new study on zebrafish by researchers at Karolinska Institutet in Sweden.

12 Dec 2022

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

An international research team led by Dr Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing techniques to incorporate into the mice a mutation of the MCT8 protein responsible for transporting thyroid hormones to the interior of the cell.

12 Dec 2022

New computer model can help researchers to spot which cells acquire alterations during development

Scientists at Johns Hopkins Medicine say they have developed a computer model - dubbed quantitative fate mapping - that looks back in the developmental timeline to trace the origin of cells in a fully grown organism

12 Dec 2022

Researchers develop new porous material capable of regenerating bones and preventing infections

Researchers from the Bioengineering and Biomaterials Laboratory of Universidad Católica de Valencia (UCV) have developed a new porous material capable of regenerating bones and preventing infections at the same time.

12 Dec 2022

An epigenetic modification improves the defense against infections, research shows

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens.

9 Dec 2022

Researchers discover a previously unknown mechanism that drives aging

Northwestern University researchers have discovered a previously unknown mechanism that drives aging.

9 Dec 2022

Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early time points.

9 Dec 2022

Better understanding of DNA repair mechanism may pave the way for effective cancer treatments

Better understanding of the mechanisms involved in DNA repair may pave the way for developing inhibitors to improve the effectiveness of radiation therapy.

9 Dec 2022

Researchers develop a virtual molecular library of thousands of 'command sentences' for cells

Using new machine learning techniques, researchers at UC San Francisco (UCSF), in collaboration with a team at IBM Research, have developed a virtual molecular library of thousands of "command sentences" for cells, based on combinations of "words" that guided engineered immune cells to seek out and tirelessly kill cancer cells.

8 Dec 2022

Study looks at the possibility of promoting hair cell regeneration using cell reprograming

About 430 million people around the world experience disabling hearing loss. In the United States, approximately 37.5 million adults report some trouble hearing. Hearing loss can happen when any part of the ear or the nerves that carry information on sounds to the brain do not work in the usual way.

8 Dec 2022

New spatial cell atlas of the developing human lung identifies 144 cell states

The developing human lung has been mapped in unprecedented detail, identifying 144 cell states in the early stages of life, and uncovering new links between developmental cells and lung cancer.

8 Dec 2022

Research explores cell receptors for bat viruses to understand emergence of zoonotic diseases

New research shows that the closest bat virus relatives of the human Middle-East Respiratory Syndrome (MERS) coronavirus efficiently bind to bat ACE2 receptors as an entry point into these cells.

8 Dec 2022

Whole genome sequencing helps construct the first blood virological profile of Chinese population

Whole genome sequencing technology can discover various known or unspecified viral sequences contained in human blood, which can provide an important database for viral infection prevention, vaccine development, viral genomic and epidemiological research.

7 Dec 2022

URI entomologist receives NIH grant to study ecological factors driving the evolution of Lyme disease bacteria in ticks

University of Rhode Island entomologist Jannelle Couret is tipping the way we understand the bacteria that causes Lyme disease.

7 Dec 2022

Salk researchers shed new light on specific mechanisms that activate oncogenes

Cancer, caused by abnormal overgrowth of cells, is the second-leading cause of death in the world. Researchers from the Salk Institute have zeroed in on specific mechanisms that activate oncogenes, which are altered genes that can cause normal cells to become cancer cells.

7 Dec 2022

Shenandoah Biotechnology introduces expanded range of CTGrade recombinant proteins manufactured following cGMP practices

Shenandoah Biotechnology Inc., a FUJIFILM Irvine Scientific company and leading manufacturer of recombinant proteins, today announced it has expanded its CTGrade portfolio of cytokines and growth factors for cell and gene therapies manufactured following cGMP guidelines.

From FUJIFILM Irvine Scientific 7 Dec 2022

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Growing human body parts in the lab is a common trope of horror movies and sci-fi books. But growing miniature organ-like tissues in the lab is already within our reach.

6 Dec 2022

New study details the neuronal response to excessive aged-related iron accumulation

Iron (Fe) accumulates in the brain cortex with aging. A plethora of studies indicate that progressive iron accumulation in the substantia nigra (SN) in the aged human brain is a major risk factor for Parkinson's disease (PD) and other neurodegenerative diseases, but not everyone.

6 Dec 2022

Cell Biology

'Cellular glue' opens the door to building tissues and organs

Report makes recommendations clarifying the ethics and oversight of chimeric research

Nanomaterial can indirectly affect the immune system via the gut microbiome, study shows

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

New computer model can help researchers to spot which cells acquire alterations during development

Researchers develop new porous material capable of regenerating bones and preventing infections

An epigenetic modification improves the defense against infections, research shows

Researchers discover a previously unknown mechanism that drives aging

Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Better understanding of DNA repair mechanism may pave the way for effective cancer treatments

Researchers develop a virtual molecular library of thousands of 'command sentences' for cells

Study looks at the possibility of promoting hair cell regeneration using cell reprograming

New spatial cell atlas of the developing human lung identifies 144 cell states

Research explores cell receptors for bat viruses to understand emergence of zoonotic diseases

Whole genome sequencing helps construct the first blood virological profile of Chinese population

URI entomologist receives NIH grant to study ecological factors driving the evolution of Lyme disease bacteria in ticks

Salk researchers shed new light on specific mechanisms that activate oncogenes

Shenandoah Biotechnology introduces expanded range of CTGrade recombinant proteins manufactured following cGMP practices

New approach enables robust intestinal mini-organs to be grown more easily in the lab

New study details the neuronal response to excessive aged-related iron accumulation

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