Cell Biology

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Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Understanding neural crest cell development will help to better comprehend craniofacial birth defects

Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations.

16 Feb 2023

Genes encoding T cell receptors vary greatly between persons and populations, study reveals

Researchers from Karolinska Institutet have discovered that the genes encoding our T cell receptors vary greatly between persons and populations, which may explain why we respond differently to for example infections.

16 Feb 2023

Ultima Genomics partners with New England Biolabs® to expand research applications on Ultima Sequencers

Ultima Genomics, Inc., a developer of a revolutionary new ultra-high throughput sequencing architecture, today announced a collaboration to develop and enable use of New England Biolabs’ (NEB®) NEBNext® reagents and library preparation kits on Ultima sequencing platforms.

From Ultima Genomics, Inc. 16 Feb 2023

Electrochemical microsensor enables real-time study of serotonin dynamics in the brain

Dysregulation of serotonin plays a role in many psychiatric disorders, including severe depression and anxiety. In the journal Angewandte Chemie, a research team has now introduced an implantable, electrochemical microsensor that makes it possible to study serotonin dynamics in the brain in real time.

16 Feb 2023

Study provides insight into the immune microenvironment around Hodgkin lymphoma tumors

The most comprehensive study to date of the blood cancer, Hodgkin lymphoma, has provided fascinating insights into what tumour cells must do to survive. Researchers from the Wellcome Sanger Institute found that cancer cells use signals to attract certain types of immune cell and instruct them not to attack.

16 Feb 2023

Brain cells may age faster in people with cocaine use disorder

A new study finds evidence from the DNA methylome that the biological age – different from the chronological age – of cells in Brodmann Area 9 of the prefrontal cortex might be greater in people with cocaine use disorder.

16 Feb 2023

First successful correction of limb length in mouse model of autosomal dominant Robinow Syndrome

Robinow Syndrome is the best known of a set of genetic disorders that affect the growth and development of the skeletal system.

15 Feb 2023

UIC scientists find new way to better target cellular proteins

By studying how enzymes move from one membrane compartment to another inside a cell, scientists at the University of Illinois Chicago have figured out a way to better target cellular proteins, which play a role in many diseases.

15 Feb 2023

Centrosome regulates nerve cell migration, study finds

Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled.

15 Feb 2023

Researchers identify a novel mechanism of DNA repair that occurs in neurons

"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age.

15 Feb 2023

Electrochemical method helps to continuously witness and analyze details of protein folding

Scientists are not yet clear on how the tau protein changes from a benign protein essential for normal function in our brains into the toxic neurofibrillary tangles that are a signature of Alzheimer's and other neurodegenerative diseases.

15 Feb 2023

B lymphocytes play a pivotal role in promoting an emergent response during infection

An SOS signals a call for immediate action during an emergency to request a need for protection. The immune system, a network of defense mechanisms, enhances protection to recover the body's internal stability.

15 Feb 2023

DeNovix celebrates sustainability award with Green CellDrop™ Automated Cell Counter Giveaway

DeNovix Inc. is giving away a Green CellDrop™ Automated Cell Counter to celebrate the instrument’s new Sustainable Laboratory Product of the Year award from SelectScience.

From DeNovix Inc. 15 Feb 2023

Drug treatment in adulthood can counteract the behavioral abnormalities typical of autism

The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular cause for this condition.

14 Feb 2023

Research details how the circadian and circannual cycles influence humans at the molecular level

The daily rotation of Earth and its yearly voyage around the Sun marks the natural rhythm of life on the planet.

13 Feb 2023

Scientists illuminate the mechanisms that prevent p53 activation from triggering cancer cell death

Cancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors and oncogenes.

13 Feb 2023

Tecan collaborates with Singular Genomics to take automated NGS library preparation into the future

Tecan has partnered with Singular Genomics to use the turnkey MagicPrep™ NGS system* to create sequencing-ready libraries for the G4™ Sequencing Platform.

From Tecan 13 Feb 2023

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

A new review was published in Genes & Cancer on February 1, 2023, entitled, "CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens."

10 Feb 2023

Study identifies a previously unknown role of 'natural killer' immune cells

Melbourne researchers have improved our understanding of how the immune system is regulated to prevent disease, identifying a previously unknown role of 'natural killer' (NK) immune cells.

10 Feb 2023

Cell Biology

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Understanding neural crest cell development will help to better comprehend craniofacial birth defects

Genes encoding T cell receptors vary greatly between persons and populations, study reveals

Ultima Genomics partners with New England Biolabs® to expand research applications on Ultima Sequencers

Electrochemical microsensor enables real-time study of serotonin dynamics in the brain

Study provides insight into the immune microenvironment around Hodgkin lymphoma tumors

Brain cells may age faster in people with cocaine use disorder

First successful correction of limb length in mouse model of autosomal dominant Robinow Syndrome

UIC scientists find new way to better target cellular proteins

Centrosome regulates nerve cell migration, study finds

Researchers identify a novel mechanism of DNA repair that occurs in neurons

Electrochemical method helps to continuously witness and analyze details of protein folding

B lymphocytes play a pivotal role in promoting an emergent response during infection

DeNovix celebrates sustainability award with Green CellDrop™ Automated Cell Counter Giveaway

Drug treatment in adulthood can counteract the behavioral abnormalities typical of autism

Research details how the circadian and circannual cycles influence humans at the molecular level

Scientists illuminate the mechanisms that prevent p53 activation from triggering cancer cell death

Tecan collaborates with Singular Genomics to take automated NGS library preparation into the future

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

Study identifies a previously unknown role of 'natural killer' immune cells

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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