Cell Biology

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Study focuses on plasticity of the synapses between the hypothalamus and hippocampus

The complexity of the human brain is unparalleled. Fortunately, thanks to constant progress in neuroscience over the past decades, we have started to make some sense of the human brain.

30 Jan 2023

Using systems biology research to alter the properties of carcinogenic cells in the lungs

KAIST (President Kwang Hyung Lee) announced on January 30th that a research team led by Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering succeeded in using systems biology research to change the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.

29 Jan 2023

Voles can form enduring attachments with mates and provide parental care without oxytocin receptors

The vital role of oxytocin - the "love hormone" - for social attachments is being called into question. More than forty years of pharmacological and behavioral research has pointed to oxytocin receptor signaling as an essential pathway for the development of social behaviors in prairie voles, humans, and other species, but a genetic study publishing in the journal Neuron on January 27 shows that voles can form enduring attachments with mates and provide parental care without oxytocin receptor signaling.

29 Jan 2023

Activated neutrophils can become potent cancer fighters

Elevated levels of immune cells, called neutrophils, in tumors have been associated with poor outcomes in people with cancer.

27 Jan 2023

Researchers identify an unexpected driver of cancer immunotherapy resistance

A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has identified an unexpected driver of cancer immunotherapy resistance: the harmful effect of chronic Type I Interferon signaling on tumor-killing CD8+ T cells.

27 Jan 2023

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

Microtubules are cellular fibres that are part of the skeleton of the cell, termed cytoskeleton. They ensure that cells maintain their shape, carry out their functions, and divide.

27 Jan 2023

Study shows mechanical tearing as a novel mechanism during neurite pruning

Nerve cells communicate with one another via long processes known as axons and dendrites, or, more generally, neurites.

26 Jan 2023

Researchers discover new transporter used by some bacteria to recycle cell wall fragments

A transporter which some bacteria use to recycle fragments of their cell wall has been discovered by researchers at Umeå university, Sweden.

26 Jan 2023

Special vascular cells sense when the brain region needs energy

When we smell hot dogs, it may trigger memories of backyard barbeques or attending baseball games during childhood.

26 Jan 2023

Scientists use next-generation protein degradation technology to study CTCF's role in transcription

CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital used a next-generation protein degradation technology to study CTCF.

26 Jan 2023

Researchers gain systematic insight into the organization of proteins in mitochondria

Mitochondria, the so-called powerhouse of the cells, are responsible for the energy supply of the organism and fulfill functions in metabolic and signaling processes.

25 Jan 2023

Altered amino acid metabolism could contribute to diabetes-associated peripheral neuropathy

Approximately half of people with type 1 or type 2 diabetes experience peripheral neuropathy - weakness, numbness, and pain, primarily in the hands and feet.

25 Jan 2023

Scientists reveal how genetic changes lead to differences in the size of cancer cells

Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered.

25 Jan 2023

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans."

25 Jan 2023

New method analyzes long-range interactions in the interactome

Researchers at the Josep Carreras Leukaemia Research Institute have developed a method to analyze long-range interactions in the DNA -the interactome- from a very low amount of starting material.

25 Jan 2023

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome - a cell's complete set of DNA - is most vulnerable while it is being duplicated before a cell divides. Cancer cells constantly are dividing, so their genomes are constantly in jeopardy.

24 Jan 2023

Cell Biology

Study focuses on plasticity of the synapses between the hypothalamus and hippocampus

Using systems biology research to alter the properties of carcinogenic cells in the lungs

Voles can form enduring attachments with mates and provide parental care without oxytocin receptors

Activated neutrophils can become potent cancer fighters

Researchers identify an unexpected driver of cancer immunotherapy resistance

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

Study shows mechanical tearing as a novel mechanism during neurite pruning

Researchers discover new transporter used by some bacteria to recycle cell wall fragments

Special vascular cells sense when the brain region needs energy

Scientists use next-generation protein degradation technology to study CTCF's role in transcription

Researchers gain systematic insight into the organization of proteins in mitochondria

Altered amino acid metabolism could contribute to diabetes-associated peripheral neuropathy

Scientists reveal how genetic changes lead to differences in the size of cancer cells

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

New method analyzes long-range interactions in the interactome

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Neurons in a bow-shaped brain region become hyperactive after chronic stress exposure

Study uncovers protein that acts as a brake for DNA replication

DNA sequencing method detects where and how small molecule drugs interact with the targeted genome

Novel method makes genetic analyses possible for all regions of the intestine

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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