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New zebrafish model provides insight into how the brain acquires essential omega-3 fatty acids

Researchers at the UCLA David Geffen School of Medicine, the Howard Hughes Medical Institute at UCLA and the National Institutes of Health have developed a zebrafish model that provides new insight into how the brain acquires essential omega-3 fatty acids, including docosahexaenoic acid (DHA) and linolenic acid (ALA).

8 May 2023

Intratumoral bacteria linked with natural purple photosynthetic bacteria show strong anticancer efficacy

Cancer remains one of the leading causes of death worldwide. Researchers are constantly looking for new therapies with improved anticancer activity, fewer side effects, and lower costs.

8 May 2023

Manipulating microglia behavior with light

An international research team, comprising scientists from DZNE, University Hospital Bonn, the Netherlands, and the US has been awarded a US$ 1.3 million grant by the "Human Frontier Science Program" to investigate brain immune cells and manipulate them via light irradiation.

5 May 2023

Breast cancer tumors disrupt the development of an immune response to favor their own growth

Researchers at Baylor College of Medicine and collaborating institutions have identified a strategy cancerous tumors use to remotely disrupt the development of an immune response that could stop their growth.

5 May 2023

GlyNAC supplementation plays beneficial role in promoting brain health and cognitive function in aging

As people get older, they aspire to live healthy lives as free as possible from the natural decline of cognitive abilities that occurs with aging.

5 May 2023

Researchers discover key immune mechanism that helps control inflammatory response to infection

Monash University researchers have discovered a key mechanism in the body's immune system that helps control the inflammatory response to infection. The discovery could help pave the way for more targeted therapies in a range of inflammatory conditions, such as autoimmunity and neuroinflammatory disease.

5 May 2023

Membrane lipid remodeling alters key enzyme involved in Alzheimer’s

Adding long-chain fatty acids can thicken cell membranes and alter the activity of a key enzyme, as LMU scientists have demonstrated in cell cultures.

4 May 2023

Powerful two-photon microscopy for imaging fast biological processes

Two-photon microscopy (TPM) has revolutionized the field of biology by enabling researchers to observe complex biological processes in living tissues at high resolution.

4 May 2023

Organoid models provide new scientific insights into a rare childhood liver cancer

Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute in the Netherlands have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer

3 May 2023

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

3 May 2023

Researchers develop a deep learning model to classify cancer cells by type

Cancer cells that initiate metastasis, or the spread of the disease from its primary location, are different from cancer cells that stay in the original tumor. Distinguishing metastasis-initiating cell types can determine the severity of cancer and help medical practitioners decide on a course of treatment.

2 May 2023

Novel chronic murine wound mouse model to study cellular senescence

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "A chronic wound model to investigate skin cellular senescence."

2 May 2023

New insight into how the occludin protein mediates cell-to-cell transmission of SARS-CoV-2 virus

While the coronavirus continues to infect people around the world, researchers at the University of Missouri have identified a specific protein inside the human body that plays a critical role in how the virus spreads from cell to cell after infection - a discovery that will help better understand the COVID-19 disease and could lead to the development of new antiviral drugs in the future.

2 May 2023

CRISPR-Cas9 system can help reduce adenovirus replication in human cells

The replication of potentially harmful adenoviruses can be significantly reduced in human cells in cell culture by using the so-called CRISPR-Cas9 system ("gene scissors")

29 Apr 2023

A dimensional reduction strategy for enhanced cryopreservation of red blood cells

Small amounts of nanometer-thin metal-organic layers efficiently protect red blood cells during freezing and thawing, as a team of researchers writing in the journal Angewandte Chemie has discovered. The nanolayers, made from metal-organic frameworks based on the metal hafnium, prevent ice crystal formation at very low concentrations. This effective novel cryoprotection mode could be used to develop new and more efficient cryoprotectants for the biosciences.

29 Apr 2023

Imbalanced electrical charges in biomolecular condensates spark redox reactions

The human body relies heavily on electrical charges. Lightning-like pulses of energy fly through the brain and nerves and most biological processes depend on electrical ions traveling across the membranes of each cell in our body.

28 Apr 2023

New approach for efficient engineering of cell and gene therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

28 Apr 2023

Researchers develop novel bio-inspired molecules to enhance bone regeneration

People's ability to regenerate bones declines with age and is further decreased by diseases such as osteoporosis.

28 Apr 2023

How inert, sleeping bacteria spring back to life

Solving a riddle that has confounded biologists since bacterial spores - inert, sleeping bacteria - were first described more than 150 years ago, researchers at Harvard Medical School have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.

27 Apr 2023

Study reveals the mechanism behind oligomeric assembly of a BAR-domain-containing protein

Cell membranes play a critical role by serving as containment units and separating the inner cellular space from the extracellular environment.

26 Apr 2023

Cell Biology

New zebrafish model provides insight into how the brain acquires essential omega-3 fatty acids

Intratumoral bacteria linked with natural purple photosynthetic bacteria show strong anticancer efficacy

Manipulating microglia behavior with light

Breast cancer tumors disrupt the development of an immune response to favor their own growth

GlyNAC supplementation plays beneficial role in promoting brain health and cognitive function in aging

Researchers discover key immune mechanism that helps control inflammatory response to infection

Membrane lipid remodeling alters key enzyme involved in Alzheimer’s

Powerful two-photon microscopy for imaging fast biological processes

Organoid models provide new scientific insights into a rare childhood liver cancer

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

Researchers develop a deep learning model to classify cancer cells by type

Novel chronic murine wound mouse model to study cellular senescence

New insight into how the occludin protein mediates cell-to-cell transmission of SARS-CoV-2 virus

CRISPR-Cas9 system can help reduce adenovirus replication in human cells

A dimensional reduction strategy for enhanced cryopreservation of red blood cells

Imbalanced electrical charges in biomolecular condensates spark redox reactions

New approach for efficient engineering of cell and gene therapies

Researchers develop novel bio-inspired molecules to enhance bone regeneration

How inert, sleeping bacteria spring back to life

Study reveals the mechanism behind oligomeric assembly of a BAR-domain-containing protein

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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