Cell Biology

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Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

19 May 2023

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

19 May 2023

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Nearly half of all cancer patients suffer from excessive weight loss due to the loss of adipose and skeletal muscle tissues, or cachexia.

18 May 2023

Liver cells can act on the central clock and modify circadian behavior

University of Queensland-led research has revealed liver cells influence the body's internal circadian clock, which was previously believed to be solely controlled by the brain.

18 May 2023

Change in liver clock could affect synchronization of the circadian cycle

Organisms rely on a biological clock known as the 'circadian' clock to regulate their activity according to the time of day.

17 May 2023

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

A pair of internationally renowned stem cell cloning experts at the University of Houston is reporting their findings of variant cells in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF) which likely represent key targets in any future therapy for the condition.

17 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

Glycosylation enzyme plays a crucial role in brain development, study shows

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

16 May 2023

Molecular mechanism behind a DNA repair pathway revealed

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

16 May 2023

New process for automated and highly accurate reporting of NGS-based clonality testing

A new research paper was published in Oncotarget's Volume 14 on May 12, 2023, entitled, "Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing."

16 May 2023

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Increased expression of musashi 1 on breast cancer cells has implication to understand dormancy and survival in bone marrow."

16 May 2023

New SEISMIC facility could improve our understanding of infectious diseases, aging and cancers

A new national research facility could significantly improve our understanding of infectious diseases, aging and cancers, leading to novel treatments and vaccines.

16 May 2023

Novel tool paves the way for automated identification and localization of proteins in cells

Electron cryo-tomography (cryo-ET) is emerging as a powerful technique to provide detailed 3D images of cellular environments and enclosed biomolecules.

15 May 2023

Weight loss leads to an increase in skeletal muscle mitochondrial energy production efficiency

Weight regains is a common problem for weight loss individuals. A number of studies have shown that weight loss in overweight people results in a reduction in whole-body energy expenditure.

15 May 2023

Phosphatases of regenerating liver play a unique role in the growth and spread of cancers

Phosphatases of regenerating liver (PRLs) are a family of enigmatic proteins involved in cell growth and metabolism present in various species.

15 May 2023

Integrated proteomics approach identifies the contents of p62 bodies in detail

Our body functioning is delicately balanced between the synthesis and breakdown of various cellular components.

15 May 2023

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

The cerebellum, a major part of the hindbrain in all vertebrates, is important for motor coordination, language acquisition, and regulating social and emotional behaviors.

15 May 2023

Study reveals how serotonin affects animal behavior at the whole-brain scale

Because serotonin is one of the primary chemicals the brain uses to influence mood and behavior, it is also the most common target of psychiatric drugs.

15 May 2023

Study sheds light on the importance of a subset of microglial cells in cognition and memory

A new study sheds light on the importance of microglia, the immune cells of the brain, in cognition and memory.

15 May 2023

Researchers create a 3D model to better understand bacteria movement

The spiral-shaped bacteria Helicobacter pylori are common and troublesome.

12 May 2023

Cell Biology

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Liver cells can act on the central clock and modify circadian behavior

Change in liver clock could affect synchronization of the circadian cycle

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

Study establishes a mechanistic link between obesity and oral cancer immune escape

Glycosylation enzyme plays a crucial role in brain development, study shows

Molecular mechanism behind a DNA repair pathway revealed

New process for automated and highly accurate reporting of NGS-based clonality testing

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

New SEISMIC facility could improve our understanding of infectious diseases, aging and cancers

Novel tool paves the way for automated identification and localization of proteins in cells

Weight loss leads to an increase in skeletal muscle mitochondrial energy production efficiency

Phosphatases of regenerating liver play a unique role in the growth and spread of cancers

Integrated proteomics approach identifies the contents of p62 bodies in detail

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

Study reveals how serotonin affects animal behavior at the whole-brain scale

Study sheds light on the importance of a subset of microglial cells in cognition and memory

Researchers create a 3D model to better understand bacteria movement

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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