Cell Biology

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T cell-mediated recognition of conserved bacterial epitope generates broad immunity

Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity.

25 Apr 2023

A new platform for testing cancer drug toxicity

For people with cancer, chemotherapy saves lives, but for some patients, the treatment comes with a side effect—heart damage.

25 Apr 2023

Study establishes a new method for examining relationships between neuron type and function

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between "test tube" data about neurons and the function of those cells in the living brain.

25 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

Exploring metabolic compatibility as a possible limiting factor to prokayrotic endosymbioses

"One of the great mysteries of biology," says Eric Libby, former SFI Postdoctoral Fellow, now an associate professor at the Integrated Science Lab (IceLab), Umeå University in Sweden, "is eukaryogenesis, or how eukaryotes arose." Scientists consider this to be a period of major evolutionary transition, critical to our understanding of the history and evolution of life on Earth.

24 Apr 2023

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

24 Apr 2023

Repair crews may move in to help fix the oxidative damage in protein factories

In a discovery fundamental to the inner workings of cells, scientists have discovered that if oxidative stress damages protein factories called ribosomes, repair crews may move in to help fix the damage so work can quickly resume.

24 Apr 2023

Researchers develop a backpack-based myeloid cell therapy for MS patients

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function to progressively decline.

21 Apr 2023

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

Researchers develop a new powerful resource to study extracellular RNA

An international team led by researchers at Baylor College of Medicine with the National Institutes of Health Extracellular RNA Communication Consortium and the Bogdan Mateescu laboratory at the ETH Zürich and University of Zürich has developed a new powerful resource to study extracellular RNA (exRNA), a novel form of cell-to-cell communication.

20 Apr 2023

Study should spur the development of alternative range of anti-TB inhibitors

Tuberculosis (TB) is one of the deadliest infectious diseases worldwide that is spread in the air like the common cold. TB is caused by the bacterium Mycobacterium tuberculosis (Mtb) and was responsible for approximately 1.6 million deaths in 2021.

20 Apr 2023

Gut bacteria could be responsible for dampening our immune response to COVID-19 vaccine

Gut bacteria that break down a sugar called fucose could be dampening our immune response to the COVID-19 mRNA vaccine, according to a study led by researchers from the Okinawa Institute of Science and Technology.

20 Apr 2023

Research reveals how a bacterial pathogen creates syringe-like structures to infect the intestines

Researchers at UT Southwestern Medical Center have discovered how a bacterium that infects people after they eat raw or undercooked shellfish creates syringe-like structures to inject its toxins into intestinal cells.

20 Apr 2023

Using engineered stem cells to treat ALS and retinitis pigmentosa

Cedars-Sinai investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

20 Apr 2023

Researchers develop novel molecular nanocages for siRNA delivery

Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases.

19 Apr 2023

Researchers compare the action of natural and therapeutic opioids

The human body naturally produces opioid-like substances, such as endorphins, which block the perception of pain and increase the feeling of well-being.

19 Apr 2023

Study reveals a previously unknown mechanism for DNA folding

A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics.

19 Apr 2023

Study advances understanding of how melanocyte stem cells work to color hair

Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.

19 Apr 2023

Research shows how exercise helps improve brain health

Physical activity is frequently cited as a means of improving physical and mental health. Researchers at the Beckman Institute for Advanced Science and Technology have shown that it may also improve brain health more directly.

19 Apr 2023

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

Cell Biology

T cell-mediated recognition of conserved bacterial epitope generates broad immunity

A new platform for testing cancer drug toxicity

Study establishes a new method for examining relationships between neuron type and function

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

Exploring metabolic compatibility as a possible limiting factor to prokayrotic endosymbioses

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Repair crews may move in to help fix the oxidative damage in protein factories

Researchers develop a backpack-based myeloid cell therapy for MS patients

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

Researchers develop a new powerful resource to study extracellular RNA

Study should spur the development of alternative range of anti-TB inhibitors

Gut bacteria could be responsible for dampening our immune response to COVID-19 vaccine

Research reveals how a bacterial pathogen creates syringe-like structures to infect the intestines

Using engineered stem cells to treat ALS and retinitis pigmentosa

Researchers develop novel molecular nanocages for siRNA delivery

Researchers compare the action of natural and therapeutic opioids

Study reveals a previously unknown mechanism for DNA folding

Study advances understanding of how melanocyte stem cells work to color hair

Research shows how exercise helps improve brain health

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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