Cell Biology

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Study elucidates the evolutionary conservation and diversification of auditory neural circuits in fruit flies

When it comes to courtship, it is important to ensure that one is interacting with a member of the same species. Animals use multiple sensory systems to confirm that potential mates are indeed suitable, with acoustic communication playing an important role in their decision making.

3 Feb 2023

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Researchers at the Hong Kong University of Science and Technology developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

New therapeutic vaccine based on an allogeneic Plasmacytoid DC cell line

A new research perspective was published in Genes & Cancer on January 30, 2023, entitled, "Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based cancer vaccines."

3 Feb 2023

The human body develops strategies to prevent the immune response from overshooting its mark

The signaling molecules of the immune system should trigger a response only where necessary. To prevent a life-threatening spread to the rest of the body, connective tissue can absorb these molecules like a sponge.

3 Feb 2023

Partially quasi-programmed diseases can be delayed by slowing aging

A new research perspective was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, entitled, "Are menopause, aging and prostate cancer diseases?"

3 Feb 2023

Researchers develop a cell line to address the challenges facing cellular modeling of disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

Improving CAR-based-immunotherapies using a molecular anchor

Adding a molecular anchor to the key protein used to recognize cancer in cellular immunotherapies can make the treatments significantly more effective.

3 Feb 2023

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

An unexpected discovery made by experts at the Brain Tumor Center at Cincinnati Children's while studying a rare-but-deadly type of brain tumor may also lead to improved treatments for several other forms of cancer that share a common influencing factor called a YAP fusion protein.

2 Feb 2023

Study offers clues about the biology of cells in the spinal cord that die off in ALS

New research offers clues about the biology of cells in the spinal cord that die off in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

2 Feb 2023

Researchers identify a gene that drives T lymphocytes to exhaustion

A research group funded by the Swiss National Science Foundation has identified a gene that drives T lymphocytes to exhaustion. This opens up new approaches for more effective immunotherapies.

2 Feb 2023

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.

2 Feb 2023

Immunomodulatory antibodies found to be successful in treating cancer when they have a looser grip

New research from the Centre for Cancer Immunology at the University of Southampton, published ahead of World Cancer Day (4 February), has shown that changing how tightly an antibody binds to a target could improve treatments for cancer.

1 Feb 2023

U of A researcher one step closer to demonstrating the potential of brain molecule to halt MS

A University of Alberta researcher is one step closer to demonstrating the potential of a brain molecule called fractalkine to halt and even reverse the effects of multiple sclerosis and other neurodegenerative diseases.

1 Feb 2023

Cochlear avatars provide a platform for deciphering the mechanisms of sensorineural hearing loss

Disabling hearing loss affects one in every ten people and up to 25% of people over 60, according to the World Health Organization, and can have both genetic and environmental causes such as infections and noise exposure.

1 Feb 2023

New discovery about "killer torpedoes" may be the next breakthrough in cancer treatment

In our body, we have both an innate immune system and an immune system that is developed throughout life. Part of the innate immune system consists of so-called NK cells.

31 Jan 2023

New technique offers a two-prong approach to attacking cancers

When noninvasive sound waves break apart tumors, they trigger an immune response in mice. By breaking down the cell wall "cloak," the treatment exposes cancer cell markers that had previously been hidden from the body's defenses, researchers at the University of Michigan have shown.

31 Jan 2023

Cell Biology

Study elucidates the evolutionary conservation and diversification of auditory neural circuits in fruit flies

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

New therapeutic vaccine based on an allogeneic Plasmacytoid DC cell line

The human body develops strategies to prevent the immune response from overshooting its mark

Partially quasi-programmed diseases can be delayed by slowing aging

Researchers develop a cell line to address the challenges facing cellular modeling of disease

Improving CAR-based-immunotherapies using a molecular anchor

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

Study offers clues about the biology of cells in the spinal cord that die off in ALS

Researchers identify a gene that drives T lymphocytes to exhaustion

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

Immunomodulatory antibodies found to be successful in treating cancer when they have a looser grip

U of A researcher one step closer to demonstrating the potential of brain molecule to halt MS

Cochlear avatars provide a platform for deciphering the mechanisms of sensorineural hearing loss

New discovery about "killer torpedoes" may be the next breakthrough in cancer treatment

New technique offers a two-prong approach to attacking cancers

Study opens new therapeutic avenues for treatment of rheumatoid arthritis

Actin influences cancer metastases in many ways

Cornell research provides new insight into chemotherapy agent's effect on DNA

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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