Cell Biology

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First small molecules designed to stimulate immune cells against neuroblastoma

An MUSC Hollings Cancer Center research team has created what team members believe to be among the first small molecules designed to stimulate immune cells to fight cancer.

28 Feb 2023

Scientists working to create revolutionary biocomputers powered by brain organoids

Artificial intelligence (AI) has long been inspired by the human brain. This approach proved highly successful: AI boasts impressive achievements – from diagnosing medical conditions to composing poetry.

28 Feb 2023

Study finds unique epigenetic biosignature in individuals with post-COVID syndrome

A reprogramming of which genes are active, and which are not, is visible in post-COVID sufferers. This is shown in a study from Linköping University, Sweden, on a small group of individuals.

28 Feb 2023

Researchers develop protein-based nanoparticles to neutralize SARS-CoV2 virus

Nanomaterials inspired by amyloid proteins are gaining interest in nanotechnology, due to their modularity, controlled self-assembly and stability.

28 Feb 2023

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

The Tecan Group and Oxford Nanopore Technologies plc (Oxford Nanopore) today announce their collaboration to drive easier high-throughput nanopore library preparation in an automated, hands-free fashion.

From Tecan 27 Feb 2023

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Nearly 100% of cases of amyotrophic lateral sclerosis - the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease - involve the buildup of a protein called TDP-43.

27 Feb 2023

Different cellular building blocks are not produced at the same time, research shows

Textbooks will tell you that in dividing cells, the production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level.

27 Feb 2023

Innate lymphoid cells educate alveolar macrophages following exposure to different viruses

A study conducted by researchers at the University of Liège on group 2 innate lymphoid cells (or ILC2s) shows that the functional reprogramming of these cells following their exposure to viruses allows our body to react differently to exposure to certain respiratory allergens.

27 Feb 2023

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

24 Feb 2023

Organoid models for research on Chinese herbal medicine

Announcing a new publication for Acta Materia Medica journal. Organoids are three-dimensional cell accusations generated from pluripotent stem cells or adult stem cells in vitro.

24 Feb 2023

Researchers successfully grow electrodes in living tissues

The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body's molecules as triggers.

24 Feb 2023

Synthetic hydrogels enable neuronal tissue growth in areas of brain damage

Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction.

24 Feb 2023

A network of interacting proteins created to aid drug discovery

Scientists at Open Targets, EMBL's European Bioinformatics Institute, and GSK are revealing the shared basis of diseases using a map of interacting human proteins.

24 Feb 2023

Novel fatty liver organoid models could aid in drug discovery and testing

Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology established novel human organoid models of fatty liver disease.

23 Feb 2023

Skipping meals can trigger a negative effect on immune cells

Fasting may be detrimental to fighting off infection, and could lead to an increased risk of heart disease, according to a new study by the Icahn School of Medicine at Mount Sinai.

23 Feb 2023

Researchers unlock the molecular basis behind fastest biological movement of single-celled eukaryotes

In his famous letter to the Royal Society dated Oct. 9, 1676, Antonie van Leeuwenhoek described a single-celled eukaryote (Vorticella) and its fascinating ultrafast cell contraction as the first set of discoveries.

22 Feb 2023

Study may elucidate metformin's potential role in longevity through DNA methylation

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 3, entitled, "Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity."

22 Feb 2023

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

22 Feb 2023

Researchers map the DNA damage in human lung cells after BaP exposure

People are occasionally exposed to potentially harmful substances in the environment or through their diets or habits. For example, a compound found in cigarette and industrial smoke, benzo(a)pyrene (BaP), is known to damage DNA.

22 Feb 2023

Dietary polyphenols may play a role in regulating inflammatory immune responses

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

Cell Biology

First small molecules designed to stimulate immune cells against neuroblastoma

Scientists working to create revolutionary biocomputers powered by brain organoids

Study finds unique epigenetic biosignature in individuals with post-COVID syndrome

Researchers develop protein-based nanoparticles to neutralize SARS-CoV2 virus

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Different cellular building blocks are not produced at the same time, research shows

Innate lymphoid cells educate alveolar macrophages following exposure to different viruses

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

Organoid models for research on Chinese herbal medicine

Researchers successfully grow electrodes in living tissues

Synthetic hydrogels enable neuronal tissue growth in areas of brain damage

A network of interacting proteins created to aid drug discovery

Novel fatty liver organoid models could aid in drug discovery and testing

Skipping meals can trigger a negative effect on immune cells

Researchers unlock the molecular basis behind fastest biological movement of single-celled eukaryotes

Study may elucidate metformin's potential role in longevity through DNA methylation

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Researchers map the DNA damage in human lung cells after BaP exposure

Dietary polyphenols may play a role in regulating inflammatory immune responses

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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