Cell Biology

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Glycosylation enzyme plays a crucial role in brain development, study shows

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

16 May 2023

Molecular mechanism behind a DNA repair pathway revealed

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

16 May 2023

New process for automated and highly accurate reporting of NGS-based clonality testing

A new research paper was published in Oncotarget's Volume 14 on May 12, 2023, entitled, "Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing."

16 May 2023

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Increased expression of musashi 1 on breast cancer cells has implication to understand dormancy and survival in bone marrow."

16 May 2023

New SEISMIC facility could improve our understanding of infectious diseases, aging and cancers

A new national research facility could significantly improve our understanding of infectious diseases, aging and cancers, leading to novel treatments and vaccines.

16 May 2023

Novel tool paves the way for automated identification and localization of proteins in cells

Electron cryo-tomography (cryo-ET) is emerging as a powerful technique to provide detailed 3D images of cellular environments and enclosed biomolecules.

15 May 2023

Weight loss leads to an increase in skeletal muscle mitochondrial energy production efficiency

Weight regains is a common problem for weight loss individuals. A number of studies have shown that weight loss in overweight people results in a reduction in whole-body energy expenditure.

15 May 2023

Phosphatases of regenerating liver play a unique role in the growth and spread of cancers

Phosphatases of regenerating liver (PRLs) are a family of enigmatic proteins involved in cell growth and metabolism present in various species.

15 May 2023

Integrated proteomics approach identifies the contents of p62 bodies in detail

Our body functioning is delicately balanced between the synthesis and breakdown of various cellular components.

15 May 2023

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

The cerebellum, a major part of the hindbrain in all vertebrates, is important for motor coordination, language acquisition, and regulating social and emotional behaviors.

15 May 2023

Study reveals how serotonin affects animal behavior at the whole-brain scale

Because serotonin is one of the primary chemicals the brain uses to influence mood and behavior, it is also the most common target of psychiatric drugs.

15 May 2023

Study sheds light on the importance of a subset of microglial cells in cognition and memory

A new study sheds light on the importance of microglia, the immune cells of the brain, in cognition and memory.

15 May 2023

Researchers create a 3D model to better understand bacteria movement

The spiral-shaped bacteria Helicobacter pylori are common and troublesome.

12 May 2023

Using an intracellular toolkit to map organelle bio-geography in stem cells

Organelles – the bits and pieces of RNA and protein within a cell – play important roles in human health and disease, such as maintaining homeostasis, regulating growth and aging, and generating energy.

12 May 2023

Vector Biolabs expands viral vector manufacturing capacity and adds to QC capabilities

Vector Biolabs, a custom design and manufacturing service provider for AAV and adenovirus viral vectors announced the completion of a facility expansion to meet growing demand.

12 May 2023

AI used to build a 3D model of the Commander complex

University of Queensland researchers have used artificial intelligence to build a 3D map of key cell components to better understand dementia and infectious diseases including COVID-19.

11 May 2023

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

When exposed to stressful conditions, several proteins tend to misfold and form aggregates inside or outside cells.

11 May 2023

Targeting uncontrolled inflammation may make tumors more responsive to treatment

Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers.

11 May 2023

New NIH program seeks to discover and catalog the breadth of somatic mosaicism in human tissues

The National Institutes of Health is launching a new program, the Common Fund's Somatic Mosaicism Across Human Tissues Network, that aims to transform our knowledge of how much genetic variation there is in the cells and tissues throughout our bodies.

11 May 2023

New approaches to promote healthspan from an epigenetic perspective

A new review paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "How can we modulate aging through nutrition and physical exercise? An epigenetic approach."

10 May 2023

Cell Biology

Glycosylation enzyme plays a crucial role in brain development, study shows

Molecular mechanism behind a DNA repair pathway revealed

New process for automated and highly accurate reporting of NGS-based clonality testing

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

New SEISMIC facility could improve our understanding of infectious diseases, aging and cancers

Novel tool paves the way for automated identification and localization of proteins in cells

Weight loss leads to an increase in skeletal muscle mitochondrial energy production efficiency

Phosphatases of regenerating liver play a unique role in the growth and spread of cancers

Integrated proteomics approach identifies the contents of p62 bodies in detail

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

Study reveals how serotonin affects animal behavior at the whole-brain scale

Study sheds light on the importance of a subset of microglial cells in cognition and memory

Researchers create a 3D model to better understand bacteria movement

Using an intracellular toolkit to map organelle bio-geography in stem cells

Vector Biolabs expands viral vector manufacturing capacity and adds to QC capabilities

AI used to build a 3D model of the Commander complex

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

Targeting uncontrolled inflammation may make tumors more responsive to treatment

New NIH program seeks to discover and catalog the breadth of somatic mosaicism in human tissues

New approaches to promote healthspan from an epigenetic perspective

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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