Cell Biology

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Researchers investigate the potential effect of folic acid supplementation on DNA mutation rates

It is well established that folic acid supplementation can significantly reduce the risk of birth defects, including neural tube defects like spina bifida, the most common birth defect of the central nervous system and the second most common of all structural birth defects.

6 Mar 2023

'Good autoantibodies' associated with a milder course and lower risk of long Covid

Sometimes in the laboratory there are unexpected results. "Previously it had been observed that autoantibodies are common in severe Covid patients, those who end up in intensive care," says Jonathan Muri, postdoctoral fellow at the Institute for Research in Biomedicine (IRB, affiliated with the Università della Svizzera italiana) and co-author of the study.

6 Mar 2023

New research pinpoints key culprit behind brain cancer metastasis in children

New research pinpoints a key cause of metastasis from an aggressive form of brain cancer in children and provides a potential new therapy for treating these tumors in the future.

6 Mar 2023

Researchers discover a new mutation that leads to arrhythmogenic cardiomyopathy

Researchers from the group of Eva van Rooij in collaboration with the UMC Utrecht identified a new mutation that leads to the cardiac disease arrhythmogenic cardiomyopathy (ACM).

5 Mar 2023

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.

3 Mar 2023

New way to carry drugs across the blood-brain barrier using nanoparticles

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Astrocytes exhibit stronger acid response with REM sleep in epileptic mice

Researchers at Tohoku University have shown that astrocytes - star-shaped glial cells that control the local ionic and metabotropic environment of the brain - exhibit an acid response with REM sleep in mice.

3 Mar 2023

Festo advances high-throughput automated pipetting with closed-loop control

Festo introduces the DHOP closed-loop pipette head for high-speed robotic pipetting applications requiring consistent volumes over a wide range of liquid viscosities. The DHOP pipette head provides the utmost in automation flexibility, speed, and feedback when devices handle many liquids.

From Festo Ltd. 2 Mar 2023

Festo breaks price/performance barriers with new multi-axis gantry

Festo introduces the EXCL, a multi-axis gantry kit that lowers acquisition, engineering, and assembly costs for automated sample handling and liquid dispensing in laboratory devices.

From Festo Ltd. 2 Mar 2023

Reprogrammed tumor cells could teach the body's immune system to fight cancer

Some cities fight gangs with ex-members who educate kids and starve gangs of new recruits. Stanford Medicine researchers have done something similar with cancer — altering cancer cells so that they teach the body's immune system to fight the very cancer the cells came from.

2 Mar 2023

Biologists discover how to awaken and reactivate neural stem cells

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons.

1 Mar 2023

Gut bacteria influence the liver's regenerative ability

When parts of the liver are removed, the body can replace the missing tissue. A team of researchers at the Technical University of Munich has now discovered that the success of this process depends to a large extent on gut bacteria.

1 Mar 2023

Newly discovered mechanism likely contributes to the severity of P. aeruginosa infections

Bacteria of the species Pseudomonas aeruginosa are antibiotic-resistant hospital germs that can enter blood, lungs and other tissues through wounds and cause life-threatening infections.

1 Mar 2023

Promising alternative strategy for islet transplantation in people with type 1 diabetes

In people with type 1 diabetes, the body's immune system attacks and destroys insulin-producing β cells that control blood glucose levels and are part of a group of cells in the pancreas called pancreatic islets.

1 Mar 2023

Key 'traffic light' mechanism controlling genetic activity within cells revealed

A major new study in the journal Nature reveals a 'traffic light' mechanism controlling genetic activity within cells – a system which could potentially be targeted by cancer drugs already in development.

1 Mar 2023

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain's protective layers - the meninges - and cause brain infection, or meningitis, a highly fatal disease.

1 Mar 2023

New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Understanding how the knee joint environment affects cartilage cells is crucial for joint health. Knowledge of cell-driven cartilage degeneration mechanisms can support the development of effective pharmaceutical interventions for osteoarthritis.

1 Mar 2023

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.

1 Mar 2023

Largest genomic study focuses on the prognosis of metastatic pheochromocytomas

Pheochromocytoma is a rare tumor, with an incidence of three to eight cases per million population per year.

28 Feb 2023

Gut-on-a-chip devices can bridge lab models and human biology

The gut is one of the most complex organs in the body. Inside, it teems with a diverse microbial population that interacts and cooperates with intestinal cells to digest food and drugs.

28 Feb 2023

Cell Biology

Researchers investigate the potential effect of folic acid supplementation on DNA mutation rates

'Good autoantibodies' associated with a milder course and lower risk of long Covid

New research pinpoints key culprit behind brain cancer metastasis in children

Researchers discover a new mutation that leads to arrhythmogenic cardiomyopathy

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

New way to carry drugs across the blood-brain barrier using nanoparticles

Astrocytes exhibit stronger acid response with REM sleep in epileptic mice

Festo advances high-throughput automated pipetting with closed-loop control

Festo breaks price/performance barriers with new multi-axis gantry

Reprogrammed tumor cells could teach the body's immune system to fight cancer

Biologists discover how to awaken and reactivate neural stem cells

Gut bacteria influence the liver's regenerative ability

Newly discovered mechanism likely contributes to the severity of P. aeruginosa infections

Promising alternative strategy for islet transplantation in people with type 1 diabetes

Key 'traffic light' mechanism controlling genetic activity within cells revealed

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Largest genomic study focuses on the prognosis of metastatic pheochromocytomas

Gut-on-a-chip devices can bridge lab models and human biology

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