Cell Biology

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CSHL researchers discover how pancreatic cancer cells develop resistance to drug treatments

Cancer cells can become resistant to treatments through adaptation, making them notoriously tricky to defeat and highly lethal. Cold Spring Harbor Laboratory Cancer Center Director David Tuveson and his team investigated the basis of "adaptive resistance" common to pancreatic cancer.

22 Jun 2021

Engineering nanobodies to fight against the SARS-CoV-2 virus

Scientists are pursuing a new strategy in the protracted fight against the SARS-CoV-2 virus by engineering nanobodies that can neutralize virus variants in two different ways.

22 Jun 2021

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

A team led by researchers at Newcastle University, UK has successfully created a model of the cells found in the lungs that can be used to replicate how COVID-19 infects the airways.

21 Jun 2021

Unrepaired DNA damage can increase the speed of aging, study suggests

Every day, our bodies face a bombardment of UV rays, ozone, cigarette smoke, industrial chemicals and other hazards.

21 Jun 2021

New method accurately detects virulent infections in advance

When viruses infect cells, changes in the cell nucleus occur, and these can be observed through fluorescence microscopy.

21 Jun 2021

Researchers unravel cellular mechanisms driving the initiation of mammary gland development

Helsinki University research group used live tissue imaging for the first time to visualize the emergence of the mammary gland.

21 Jun 2021

Researchers identify four substances that inhibit SARS-CoV-2 replication in cells

Researchers from the German Center for Infection Research at Charité - Universitätsmedizin Berlin and the University of Bonn have examined the way in which SARS-CoV-2 reprograms the metabolism of the host cell in order to gain an overall advantage.

21 Jun 2021

New technique can measure metabolic process at the single-cell level

Understanding cellular metabolism - how a cell uses energy- could be key to treating a wide array of diseases, including vascular diseases and cancer.

18 Jun 2021

Yeast cell machinery seamlessly 'reads' the unnatural ingredients in the genetic recipe

If the genome is the recipe of life, base pairs are the individual ingredients listed. These chemical structures form DNA, and every living organism on Earth has just four. The specific arrangements of these four base pairs -- A, T, C, G -- make us who and what we are.

18 Jun 2021

Study: Cancer cells grown in culture dishes have less parity with their human sources

In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new computer-based technique showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.

18 Jun 2021

Novel peptide-based hydrogels hold great promise for tissue engineering applications

Tissue-engineering scaffolds built around ultrashort peptides provide a new platform for studying bone regeneration in the lab.

17 Jun 2021

Scientists decipher the activation mechanism of a chemokine receptor

Chemokine receptors, located at the surface of many immune cells, play an important role in their function. Chemokines are small proteins that bind to these receptors and control the movement and behavior of white blood cells.

16 Jun 2021

Researchers identify properties that enable proteins to remember and respond to pressure

A new rubber band stretches, but then snaps back into its original shape and size. Stretched again, it does the same. But what if the rubber band was made of a material that remembered how it had been stretched? Just as our bones strengthen in response to impact, medical implants or prosthetics composed of such a material could adjust to environmental pressures such as those encountered in strenuous exercise.

16 Jun 2021

Study finds molecular switch that controls the ability of organisms to adapt to low nutrient levels

Getting energy and nutrients from the environment - that is, eating - is such an important function that it has been regulated through sophisticated mechanisms over hundreds of millions of years. Some of these mechanisms are only now beginning to be unraveled.

16 Jun 2021

Cell Biology

CSHL researchers discover how pancreatic cancer cells develop resistance to drug treatments

Engineering nanobodies to fight against the SARS-CoV-2 virus

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

Unrepaired DNA damage can increase the speed of aging, study suggests

New method accurately detects virulent infections in advance

Researchers unravel cellular mechanisms driving the initiation of mammary gland development

Researchers identify four substances that inhibit SARS-CoV-2 replication in cells

New technique can measure metabolic process at the single-cell level

Yeast cell machinery seamlessly 'reads' the unnatural ingredients in the genetic recipe

Study: Cancer cells grown in culture dishes have less parity with their human sources

Novel peptide-based hydrogels hold great promise for tissue engineering applications

Scientists decipher the activation mechanism of a chemokine receptor

Researchers identify properties that enable proteins to remember and respond to pressure

Study finds molecular switch that controls the ability of organisms to adapt to low nutrient levels

Researchers explore potential exposure to microbial agents in-utero

Using natural killers from the immune system to target breast cancer cells

P-glycoprotein shows ability to remove a toxin associated with Alzheimer's from the brain

Precise manipulation of folate metabolism may pave way to broadly improve health during aging

Researchers report on the role of brain cell membranes' lipids in Alzheimer's progression

New AI model could help predict which viruses are likely to spread from animals to humans

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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