Cell Biology

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Study suggests GILZ protein as a promising anti-hepatic fibrosis drug target

Scientists from Russia and Italy studied a new axis of the pathway that prevents the development of liver fibrosis. The role of GILZ protein in curbing the disease progression was shown in a study using mice models and confirmed by clinical data.

5 May 2021

Penn State researchers develop a way to study microenvironment of breast cancer in 3D

Cancerous tumors thrive on blood, extending their roots deep into the fabric of the tissue of their host. They alter the genetics of surrounding cells and evolve to avoid the protective attacks of immune cells.

4 May 2021

Study investigates how Brd4 influences diet-induced obesity

A new study, published in JCI Insight, looks at how Brd4, a regulator of the innate immune response, influences diet-induced obesity.

4 May 2021

Study uncovers protein 'signature' of severe COVID-19

Researchers at Massachusetts General Hospital have identified the protein "signature" of severe COVID-19, which they describe in a new study published in Cell Reports Medicine.

4 May 2021

New combination treatment could benefit T-ALL patients who do not respond to chemotherapy

T-cell acute lymphoblastic leukemia is an aggressive cancer type that mostly affects children. The standard treatment is chemotherapy, but about one in four patients do not respond or develop resistance to this.

4 May 2021

Certain immune cells can cause damage to the aging nervous system, study finds

Aging is the biggest risk factor for perturbation of the nervous system, even in the absence of distinct disease or trauma.

4 May 2021

Increasing sodium and calcium levels in the bloodstream helps prevent deadly arrhythmias

Blood may seem like a simple fluid, but its chemistry is complex. When too much potassium, for instance, accumulates in the bloodstream, patients may experience deadly irregular heart rhythms.

4 May 2021

Study shows potential of human mesenchymal stem cells to treat chronic lung infections

A study released today in STEM CELLS Translational Medicine offers hope for those suffering from a chronic, difficult to treat condition called non-tuberculous mycobacteria (NTM) lung infection.

4 May 2021

Tiny 3D brain models could accelerate drug research for multiple sclerosis

Tiny 3-D models that mimic vital aspects of the human nervous system have been developed in a step that could accelerate drug research for neurological conditions such as multiple sclerosis (MS).

3 May 2021

Correcting mutations in muscle stem cells using new gene-editing technology

A new gene-editing technique can be used to correct mutations in muscle stem cells, paving the way for the first potential cell therapy for genetic muscle disorders.

30 Apr 2021

Too much salt affects the functioning of phagocytes

For many of us, adding salt to a meal is a perfectly normal thing to do. We don't really think about it. But actually, we should. As well as raising our blood pressure, too much salt can severely disrupt the energy balance in immune cells and stop them from working properly.

30 Apr 2021

Researchers identify important factor in the development of dendritic cells

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease. These include the dendritic cells.

30 Apr 2021

Researchers reveal how the brain may adapt to processing complex information

Human decision-making depends on the flexible processing of complex information, but how the brain may adapt processing to momentary task demands has remained unclear.

29 Apr 2021

Single protein could be a new target for delaying onset of aging symptoms in the brain

It is not every day that scientists come across a phenomenon so fundamental that it is observed across fruit flies, rodents and humans.

29 Apr 2021

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

Researchers at University of California San Diego School of Medicine have discovered one way in which SARS-CoV-2, the coronavirus that causes COVID-19, hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.

29 Apr 2021

New collaboration to study early detection of developmental differences in children

The University of Washington's School of Medicine Brotman Baty Institute for Precision Medicine is collaborating with Illumina, Inc. and GeneDx, Inc., a wholly owned subsidiary of BioReference Laboratories, Inc., an OPKO Health company, to study early detection of developmental differences in children.

29 Apr 2021

Using light-activated 3D printing to manufacture self-healing hydrogels with complex architectures

The scientific community is focusing its research into the multiple applications of Hydrogels, polymeric materials which contains a large amount of water, that have the potential to reproduce the features of biological tissues.

29 Apr 2021

Researchers investigate how the brain's circadian rhythm control center regulates behavior

Our bodies and behaviors often seem to have rhythms of their own. Why do we go to the bathroom at the same time every day? Why do we feel off if we can't go to sleep at the right time? Circadian rhythms are a behind-the-scenes force that shape many of our behaviors and our health.

28 Apr 2021

New method could be used to develop more effective treatments for cancer, metabolic disorders

Researchers from the University of Copenhagen have developed a new method that makes it possible to control human hormones and metabolism.

28 Apr 2021

Researchers develop first 3D organoid models of the pancreas from human stem cells

This year, more than 60,000 adults in the United States will be diagnosed with pancreatic cancer and, statistically, as few as 10 percent will survive five years after diagnosis, according to the American Cancer Society.

28 Apr 2021

Cell Biology

Study suggests GILZ protein as a promising anti-hepatic fibrosis drug target

Penn State researchers develop a way to study microenvironment of breast cancer in 3D

Study investigates how Brd4 influences diet-induced obesity

Study uncovers protein 'signature' of severe COVID-19

New combination treatment could benefit T-ALL patients who do not respond to chemotherapy

Certain immune cells can cause damage to the aging nervous system, study finds

Increasing sodium and calcium levels in the bloodstream helps prevent deadly arrhythmias

Study shows potential of human mesenchymal stem cells to treat chronic lung infections

Tiny 3D brain models could accelerate drug research for multiple sclerosis

Correcting mutations in muscle stem cells using new gene-editing technology

Too much salt affects the functioning of phagocytes

Researchers identify important factor in the development of dendritic cells

Researchers reveal how the brain may adapt to processing complex information

Single protein could be a new target for delaying onset of aging symptoms in the brain

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

New collaboration to study early detection of developmental differences in children

Using light-activated 3D printing to manufacture self-healing hydrogels with complex architectures

Researchers investigate how the brain's circadian rhythm control center regulates behavior

New method could be used to develop more effective treatments for cancer, metabolic disorders

Researchers develop first 3D organoid models of the pancreas from human stem cells

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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