Cell Biology

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Auto-aggressive immune cells cause liver immune pathology in non-alcoholic steatohepatitis

Non-alcoholic steatohepatitis (NASH), often called 'fatty liver hepatitis', can lead to serious liver damage and liver cancer.

24 Mar 2021

Researchers discover a novel marker of adult human neural stem cells

The mammalian center for learning and memory, hippocampus, has a remarkable capacity to generate new neurons throughout life. Newborn neurons are produced by neural stem cells (NSCs) and they are crucial for forming neural circuits required for learning and memory, and mood control.

24 Mar 2021

Researchers produce a detailed molecular atlas of lung development

Researchers at the Perelman School of Medicine at the University of Pennsylvania have produced a detailed molecular atlas of lung development, which is expected to be a fundamental reference in future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs.

24 Mar 2021

Study provides groundbreaking insights into the passage of sodium ions through potassium channels

Ion selectivity is an important property of cell membrane ion channels. For example, potassium ion channels are more permeable to potassium ions than to sodium ions.

24 Mar 2021

Research identifies ways to prevent coronavirus spread to the nervous system

A number of studies have shown that human coronaviruses, including SARS-CoV-2 which causes COVID-19, appear to attack neurons and the nervous system in vulnerable populations.

23 Mar 2021

Cellular senescence of cancer-associated fibroblasts play a key role in peritoneal dissemination

Through an analysis of cellular components (cell fractions) from malignant ascites (fluid buildup in the abdomen caused by gastric cancer), a research collaboration based in Kumamoto University (Japan) has demonstrated that cellular senescence of cancer-associated fibroblasts (CAFs) play an important role in the peritoneal dissemination of gastric cancer foci (cells different from surrounding cells).

23 Mar 2021

Computational analysis reveals why new SARS-CoV-2 variants bind better to human cells

All viruses mutate as they make copies of themselves to spread and thrive. SARS-CoV-2, the virus the causes COVID-19, is proving to be no different. There are currently more than 4,000 variants of COVID-19, which has already killed more than 2.7 million people worldwide during the pandemic.

23 Mar 2021

Post-COVID-19 blood clots may be caused by lingering immune response in blood vessels

Serious complications due to blood clots, such as heart attacks and strokes, that are experienced by some COVID-19 survivors may be caused by a lingering immune response in the blood vessels after recovery, suggests a study published today in eLife.

23 Mar 2021

‘Zombie’ cells come to life after the death of the brain

In the hours after we die, certain cells in the human brain are still active. Some cells even increase their activity and grow to gargantuan proportions, according to new research from the University of Illinois Chicago.

23 Mar 2021

Gene responsible for cholesterol dysregulation in brain cancer cells could be a target for future drugs

Most people relate cholesterol to heart health, but it is also a critical component in the growth and spread of brain cancer.

23 Mar 2021

Over-expression of LRRN4CL gene linked to metastasis of certain cancers to the lungs

A gene not previously linked to cancer has been shown to play a key role in the spread of certain cancers to the lungs, new research from scientists at the Wellcome Sanger Institute has shown.

23 Mar 2021

Stem cell therapy could help restore debilitating age-related muscle loss

As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss that happens with age.

23 Mar 2021

Speakers Announced for Virtual Experimental Biology 2021 Meeting

Renowned scientists—including Nobel laureates, research pioneers, and celebrated educators—will speak at the virtual Experimental Biology (EB) 2021 meeting, to be held April 27–30.

23 Mar 2021

Star-shaped brain cells impact the length and depth of sleep in mice

For something we spend one-third of our lives doing, we still understand remarkably little about how sleep works -- for example, why can some people sleep deeply through any disturbance, while others regularly toss and turn for hours each night? And why do we all seem to need a different amount of sleep to feel rested?

22 Mar 2021

Direct differentiation of progenitor stem-like cells into mesenchymal stem, and osteogenic cells

Epithelial cell rests of Malassez derived from the periodontal ligament were transformed into progenitor stem-like cells by stimulation with epigenetic agents.

22 Mar 2021

First model of early human embryo generated from skin cells

In a discovery that will revolutionise research into the causes of early miscarriage, infertility and the study of early human development - an international team of scientists led by Monash University in Melbourne, Australia has generated a model of a human embryo from skin cells.

22 Mar 2021

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

A new peer-reviewed study published in the journal Toxicological Research & Application shows acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression compared to smoke from combustible cigarettes.

21 Mar 2021

Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

Most drugs operate via the membranes that surround the body's cells. A study by researchers at Karolinska Institutet in Sweden has now mapped the structure and mechanism of MGST2, a membrane enzyme that, amongst other things, plays a part in chronic inflammation and cancer.

20 Mar 2021

New cellular device with computing capacity could be used outside the laboratory

The Research Group on Synthetic Biology for Biomedical Applications at Pompeu Fabra University in Barcelona, Spain, has designed a cellular device capable of computing by printing cells on paper. For the first time, they have developed a living device that could be used outside the laboratory without a specialist, and it could be produced on an industrial scale at low cost.

20 Mar 2021

Researchers describe a new approach to treating Parkinson's disease

Parkinson's disease is the second most common, age-related, neurodegenerative disease: In Germany alone, about 300,000 people are affected and experience sometimes major limitations to their quality of life.

20 Mar 2021

Cell Biology

Auto-aggressive immune cells cause liver immune pathology in non-alcoholic steatohepatitis

Researchers discover a novel marker of adult human neural stem cells

Researchers produce a detailed molecular atlas of lung development

Study provides groundbreaking insights into the passage of sodium ions through potassium channels

Research identifies ways to prevent coronavirus spread to the nervous system

Cellular senescence of cancer-associated fibroblasts play a key role in peritoneal dissemination

Computational analysis reveals why new SARS-CoV-2 variants bind better to human cells

Post-COVID-19 blood clots may be caused by lingering immune response in blood vessels

‘Zombie’ cells come to life after the death of the brain

Gene responsible for cholesterol dysregulation in brain cancer cells could be a target for future drugs

Over-expression of LRRN4CL gene linked to metastasis of certain cancers to the lungs

Stem cell therapy could help restore debilitating age-related muscle loss

Speakers Announced for Virtual Experimental Biology 2021 Meeting

Star-shaped brain cells impact the length and depth of sleep in mice

Direct differentiation of progenitor stem-like cells into mesenchymal stem, and osteogenic cells

First model of early human embryo generated from skin cells

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

New cellular device with computing capacity could be used outside the laboratory

Researchers describe a new approach to treating Parkinson's disease

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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