Cell Biology

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A highly conserved protein contributes to sensing mechanical pain, study shows

Researchers at McGill University have discovered that a protein found in the membrane of our sensory neurons are involved in our capacity to feel mechanical pain, laying the foundation for the development of powerful new analgesic drugs.

24 Feb 2020

DNA topological problems may cause lymphoma, study shows

Researchers from the Spanish National Cancer Research Centre, Madrid, and the Andalusian Molecular Biology and Regenerative Medicine Centre, Seville, published today a paper in Nature Communications that shows that DNA topological problems may cause endogenous DNA breaks that have a causal relationship with cancer.

24 Feb 2020

Breast cancer cells hibernate in the lung before forming secondary tumors

Healthy lung cells support the survival of breast cancer cells, allowing them to hibernate in the lung before forming secondary tumors, according to new research from the Crick.

24 Feb 2020

Researchers discover glial cells that control stress response, extend lifespan in worms

While many of us worry about proteins aggregating in our brains as we age and potentially causing Alzheimer's disease or other types of neurodegeneration, we may not realize that some of the same proteins are aggregating in our muscles, setting us up for muscle atrophy in old age.

23 Feb 2020

Researchers develop new probe to detect common target of anti-inflammatory drugs

The Chan group at the Beckman Institute for Advanced Science and Technology has recently developed a probe named CoxFluor, which is able to distinguish between Cyclooxygenase-2, an enzyme that plays a major role in driving the progression of cancer, and Cyclooxygenase-1, which is expressed in all cells.

23 Feb 2020

Researchers decipher the mechanism that regulates organ size and shape

A study by IRB Barcelona´s Development and Growth Control Laboratory, headed by ICREA researcher Marco Milán, reveals how Dpp and Wg morphogens regulate organ proportions and patterning of the fly wing through independent mechanisms.

23 Feb 2020

Novel discovery about enzymes ensures efficient DNA repair

DNA is the hereditary material in humans, a unique cookbook of who we are. This is where you'll find the answer as to why you have your specific eye and hair color, or perhaps why you sunburn easily.

23 Feb 2020

Technique used to study human epidemiology reveals coral disease risk factors

In a study published in Scientific Reports, a team of international researchers led by University of Hawaii at Mānoa postdoctoral fellow Jamie Caldwell used a statistical technique typically employed in human epidemiology to determine the ecological risk factors affecting the prevalence of two coral diseases--growth anomalies, abnormalities like coral tumors, and white syndromes, infectious diseases similar to flesh-eating bacteria.

23 Feb 2020

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

Using 'mini-brains' to detect harmful neurodevelopmental effects of antidepressant

Researchers at Johns Hopkins Bloomberg School of Public Health have demonstrated the use of stem-cell-derived "mini-brains" to detect harmful side effects of a common drug on the developing brain.

21 Feb 2020

Isolating Single T-cells of Interest using an Optofluidic Platform

Researchers are in desperate need of single-cell analysis techniques and those that allow the isolation of high-value T-cells for research and development.

From Bruker Cellular Analysis 21 Feb 2020

DeNovix to give away special edition Pink CellDrop Automated Cell Counter

DeNovix Inc.

From DeNovix Inc. 21 Feb 2020

New label-free microscopic techniques provide better visualization of extracellular vesicles

The Biophotonics Imaging Lab at the Beckman Institute for Advanced Science and Technology has developed imaging techniques that investigate tissues without using any staining or labels.

21 Feb 2020

Researchers map the cellular diversity of entire salivary gland tumors

What goes on inside and between individual cells during the very earliest stages of tumor development? Single cell sequencing technologies and a mouse model have enabled researchers to comprehensively map the cellular diversity of whole salivary gland tumors and trace the path of cancer stem cells.

20 Feb 2020