Cell Biology

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New Endothelial Cell Atlas can be used to improve treatments for many diseases

New surprising knowledge on endothelial cells in a dozen different murine tissues is now available in an open access, user-friendly, database for professionals.

20 Feb 2020

Statistical modeling technique helps track tumor cell diversity

Cancer cells are a wily adversary. One reason the disease outfoxes many potential treatments is because of the diversity of the cancer cell population. Researchers have found this population difficult to characterize and quantify.

20 Feb 2020

Plant-based relatives of cholesterol could boost gene-infused nanoparticle delivery

Gene-infused nanoparticles used for combating disease work better when they include plant-based relatives of cholesterol because their shape and structure help the genes get where they need to be inside cells.

20 Feb 2020

Scientists discover novel molecular pathway involved in immunotherapy response

Scientists at The Wistar Institute discovered a novel pathway that enables detection of DNA in the cytoplasm and triggers inflammation and cellular senescence.

20 Feb 2020

New C. elegans model will accelerate study of a rare disease

The model will permit to accelerate and reduce the price of the research, which is studying the mechanisms and the possible pharmacological targets for the neuronal alterations of this disease.

20 Feb 2020

Altered potassium levels in neurons linked to mood swings in bipolar patients

People with bipolar disorder experience dramatic shifts in mood, oscillating between often debilitating periods of mania and depression.

19 Feb 2020

Researchers identify protein that maintains balance between protrusive and contractile machineries

Tropomodulin maintains the fine balance between the protein machineries responsible for cell movement and morphogenesis.

18 Feb 2020

Study reveals how cells remove misfolded proteins from tissues

Researchers in Japan have identified a new quality control system that allows cells to remove damaged and potentially toxic proteins from their surroundings.

18 Feb 2020

Live-cell imaging provides new insights into dynamic structure of mitochondria

As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. Until now, it has been assumed that these functions underlie a static structure of mitochondrial membranes.

18 Feb 2020

Fruit flies have a new defense strategy to deal with oxidative stress

Oxidative stress affects all living organisms, and the damage it causes is believed to play a part in cancer, diabetes, Alzheimer's disease and a number of other health conditions.

18 Feb 2020

New 3D model shows how breast cancer cells interact with the body’s stem cells

A Loughborough University Ph.D. student has provided new insight into how breast cancer cells interact with cells in our body by using a novel 3D model.

18 Feb 2020

Detailed maps of breast cancer reveal how genetic changes shape the tumor landscape

Scientists have created one of the most detailed maps of breast cancer ever achieved, revealing how genetic changes shape the physical tumor landscape, according to research funded by Cancer Research UK and published in Nature Cancer today (Monday).

17 Feb 2020

New technology enables scientists to analyze behavior of cancer cells in lab-grown tumors

New technology developed at UCL is, for the first time, enabling cancer scientists to analyze the individual behavior of millions of different cells living inside lab-grown tumors - a breakthrough which could lead to new personalised cancer treatments.

17 Feb 2020

Oxidative stress induces sleep in fruit flies, research shows

Sleep-deprived fruit flies helped reveal what induces sleep. University of Oxford researchers Anissa Kempf, Gero Miesenböck, and colleagues reveal that fruit fly sleep is driven by oxidative stress, the imbalance of free radicals and antioxidants in the body. Kempf

16 Feb 2020

Dormancy emerges as a natural evolutionary response to over-predation, study finds

Why do predators sometimes lay dormant eggs -- eggs which are hardy, but take a long time to hatch, and are expensive to produce?

16 Feb 2020

New biological tool can detect and debug faulty genetic circuits

Every cell in our body has a computer-like control system that sends biological signals through thousands of circuits to monitor the cell's needs and regulate its responses.

16 Feb 2020

Unique reproductive trait for seagrass revealed

Seagrasses have long been known as some of Earth's most remarkable organisms--descendants of flowering land plants that have re-colonized the ocean by developing traits that allow them to grow, pollinate, and release seeded fruits while fully immersed in salty seawater.

16 Feb 2020