Cell Biology

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Researchers develop new probe to detect common target of anti-inflammatory drugs

The Chan group at the Beckman Institute for Advanced Science and Technology has recently developed a probe named CoxFluor, which is able to distinguish between Cyclooxygenase-2, an enzyme that plays a major role in driving the progression of cancer, and Cyclooxygenase-1, which is expressed in all cells.

23 Feb 2020

Researchers decipher the mechanism that regulates organ size and shape

A study by IRB Barcelona´s Development and Growth Control Laboratory, headed by ICREA researcher Marco Milán, reveals how Dpp and Wg morphogens regulate organ proportions and patterning of the fly wing through independent mechanisms.

23 Feb 2020

Novel discovery about enzymes ensures efficient DNA repair

DNA is the hereditary material in humans, a unique cookbook of who we are. This is where you'll find the answer as to why you have your specific eye and hair color, or perhaps why you sunburn easily.

23 Feb 2020

Technique used to study human epidemiology reveals coral disease risk factors

In a study published in Scientific Reports, a team of international researchers led by University of Hawaii at Mānoa postdoctoral fellow Jamie Caldwell used a statistical technique typically employed in human epidemiology to determine the ecological risk factors affecting the prevalence of two coral diseases--growth anomalies, abnormalities like coral tumors, and white syndromes, infectious diseases similar to flesh-eating bacteria.

23 Feb 2020

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

Using 'mini-brains' to detect harmful neurodevelopmental effects of antidepressant

Researchers at Johns Hopkins Bloomberg School of Public Health have demonstrated the use of stem-cell-derived "mini-brains" to detect harmful side effects of a common drug on the developing brain.

21 Feb 2020

Isolating Single T-cells of Interest using an Optofluidic Platform

Researchers are in desperate need of single-cell analysis techniques and those that allow the isolation of high-value T-cells for research and development.

From Bruker Cellular Analysis 21 Feb 2020

DeNovix to give away special edition Pink CellDrop Automated Cell Counter

DeNovix Inc.

From DeNovix Inc. 21 Feb 2020

New label-free microscopic techniques provide better visualization of extracellular vesicles

The Biophotonics Imaging Lab at the Beckman Institute for Advanced Science and Technology has developed imaging techniques that investigate tissues without using any staining or labels.

21 Feb 2020

Researchers map the cellular diversity of entire salivary gland tumors

What goes on inside and between individual cells during the very earliest stages of tumor development? Single cell sequencing technologies and a mouse model have enabled researchers to comprehensively map the cellular diversity of whole salivary gland tumors and trace the path of cancer stem cells.

20 Feb 2020

Scientists make important discovery with implications for people living with AMD

Scientists from Trinity College Dublin have made an important discovery with implications for those living with a common, debilitating eye disease (age-related macular degeneration, AMD) that can cause blindness.

20 Feb 2020

New Endothelial Cell Atlas can be used to improve treatments for many diseases

New surprising knowledge on endothelial cells in a dozen different murine tissues is now available in an open access, user-friendly, database for professionals.

20 Feb 2020

Statistical modeling technique helps track tumor cell diversity

Cancer cells are a wily adversary. One reason the disease outfoxes many potential treatments is because of the diversity of the cancer cell population. Researchers have found this population difficult to characterize and quantify.

20 Feb 2020

Plant-based relatives of cholesterol could boost gene-infused nanoparticle delivery

Gene-infused nanoparticles used for combating disease work better when they include plant-based relatives of cholesterol because their shape and structure help the genes get where they need to be inside cells.

20 Feb 2020

Scientists discover novel molecular pathway involved in immunotherapy response

Scientists at The Wistar Institute discovered a novel pathway that enables detection of DNA in the cytoplasm and triggers inflammation and cellular senescence.

20 Feb 2020

New C. elegans model will accelerate study of a rare disease

The model will permit to accelerate and reduce the price of the research, which is studying the mechanisms and the possible pharmacological targets for the neuronal alterations of this disease.

20 Feb 2020

Altered potassium levels in neurons linked to mood swings in bipolar patients

People with bipolar disorder experience dramatic shifts in mood, oscillating between often debilitating periods of mania and depression.

19 Feb 2020

Researchers identify protein that maintains balance between protrusive and contractile machineries

Tropomodulin maintains the fine balance between the protein machineries responsible for cell movement and morphogenesis.

18 Feb 2020

Study reveals how cells remove misfolded proteins from tissues

Researchers in Japan have identified a new quality control system that allows cells to remove damaged and potentially toxic proteins from their surroundings.

18 Feb 2020

Live-cell imaging provides new insights into dynamic structure of mitochondria

As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. Until now, it has been assumed that these functions underlie a static structure of mitochondrial membranes.

18 Feb 2020

Cell Biology

Researchers develop new probe to detect common target of anti-inflammatory drugs

Researchers decipher the mechanism that regulates organ size and shape

Novel discovery about enzymes ensures efficient DNA repair

Technique used to study human epidemiology reveals coral disease risk factors

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Using 'mini-brains' to detect harmful neurodevelopmental effects of antidepressant

Isolating Single T-cells of Interest using an Optofluidic Platform

DeNovix to give away special edition Pink CellDrop Automated Cell Counter

New label-free microscopic techniques provide better visualization of extracellular vesicles

Researchers map the cellular diversity of entire salivary gland tumors

Scientists make important discovery with implications for people living with AMD

New Endothelial Cell Atlas can be used to improve treatments for many diseases

Statistical modeling technique helps track tumor cell diversity

Plant-based relatives of cholesterol could boost gene-infused nanoparticle delivery

Scientists discover novel molecular pathway involved in immunotherapy response

New C. elegans model will accelerate study of a rare disease

Altered potassium levels in neurons linked to mood swings in bipolar patients

Researchers identify protein that maintains balance between protrusive and contractile machineries

Study reveals how cells remove misfolded proteins from tissues

Live-cell imaging provides new insights into dynamic structure of mitochondria

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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