Cell Biology

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Cancer genes’ mutational status influenced by their evolutionary age, regulatory functions

Researchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulated) by specific mechanisms during cancer development.

26 Feb 2019

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences, and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases.

26 Feb 2019

'Chromosome scanner' that protects against cancer identified

In a new study, researchers from the University of Copenhagen have identified one of the main mechanisms behind the repair of serious damage to the human DNA. A 'scanner' inside the cells decides whether or not so-called flawless DNA repair, which protects against cancer, is launched.

26 Feb 2019

Researchers map molecules and functions of skin from tissue samples

The skin constitutes the barrier between the body and the outside world. The skin serves various purposes and it protects the body from external impact such as heat, cold, radiation or bacteria while maintaining a stable environment inside the body.

26 Feb 2019

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

As the biomedical field races to develop therapies based on an individual's genetic makeup, a City of Hope scientist and his colleagues found that some commercial cell lines used for countless laboratory studies have mislabeled ancestry when it comes to minorities.

25 Feb 2019

Disease X: an unknown disease that could claim millions of lives

Dubbed ‘Disease X’, scientists believe a future epidemic of the influenza virus could cause millions of deaths worldwide.

25 Feb 2019

Porvair announces availability of US-manufactured sample storage microplate

Porvair Sciences announces that its industry standard 96-well sample storage plate - the round bottom 1ml deep well microplate is now available manufactured in the USA.

From Porvair Sciences Limited 25 Feb 2019

New technology platform digitally counts growth factors in single cells

Whether healthy or diseased, human cells exhibit behaviors and processes that are largely dictated by growth factor molecules, which bind to receptors on the cells. For example, growth factors tell the cells to divide, move, and when to die--a process known as apoptosis.

23 Feb 2019

The gene-edited twins born in China may have altered cognition and memory

A new study has fuelled further concerns over the controversial gene-editing experiment that was performed in China last year.

22 Feb 2019

Study finds out similarity in function between healthy retina cell and tumor cell

How is a healthy retina cell like a tumor cell? It hijacks an energy-producing chemical reaction to churn out molecular building blocks. When tumor cells do it, they use the building blocks to make cancer grow and spread. But when retina cells do it, they renew photoreceptor membranes that keep our vision sharp.

22 Feb 2019

Akna protein plays a key role in the regulation of neural stem cells

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine.

22 Feb 2019

Researchers uncover interspecies communication between gut bacteria and host

Bacteria in the gut do far more than help digest food in the stomachs of their hosts, they can also tell the genes in their mammalian hosts what to do.

22 Feb 2019

Study offers new insights into mechanisms of changes in erythrocytes under stress

Various stress effects make an integral part of modern life, and their minimization is of particular relevance.

22 Feb 2019

Mitochondrial proteotoxicity appears to be epicentre of molecular pathogenesis

Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins.

22 Feb 2019

Newly designed molecule could benefit people with Friedrich's Ataxia

Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A radiation in laboratory tests, than those from a healthy population, according to new research from the University of Bath.

21 Feb 2019

Dietary fiber helps to aggregate gut particles, study shows

Food, microbes, and medicine all clump together as they move through our gut. Sticky molecules secreted into our intestines bind the gut particles in the same way that flour holds a ball of dough together.

21 Feb 2019

Reduced antibody adaptability may make the elderly more vulnerable to influenza

The influenza vaccine may be less effective in the elderly because their B cells are less capable of producing antibodies that can adapt to protect against new viral strains, researchers report February 19 in the journal Cell Host & Microbe.

21 Feb 2019

Novel ratiometric fluorescent probe for studying cellular activity of anticancer drug

NUS chemists have developed a novel ratiometric fluorescent probe for studying cellular activity of the clinically important anticancer drug cisplatin for next generation drug development.

21 Feb 2019

Scientists uncover new mechanisms regulating neural stem cells

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine. Scientists at Helmholtz Zentrum München and Ludwig Maximilian University of Munich have discovered that the protein Akna plays a key role in this process.

21 Feb 2019

Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A Salk Institute discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead to a treatment for Alzheimer's disease based on a compound found in nature.

21 Feb 2019

Cell Biology

Cancer genes’ mutational status influenced by their evolutionary age, regulatory functions

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

'Chromosome scanner' that protects against cancer identified

Researchers map molecules and functions of skin from tissue samples

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

Disease X: an unknown disease that could claim millions of lives

Porvair announces availability of US-manufactured sample storage microplate

New technology platform digitally counts growth factors in single cells

The gene-edited twins born in China may have altered cognition and memory

Study finds out similarity in function between healthy retina cell and tumor cell

Akna protein plays a key role in the regulation of neural stem cells

Researchers uncover interspecies communication between gut bacteria and host

Study offers new insights into mechanisms of changes in erythrocytes under stress

Mitochondrial proteotoxicity appears to be epicentre of molecular pathogenesis

Newly designed molecule could benefit people with Friedrich's Ataxia

Dietary fiber helps to aggregate gut particles, study shows

Reduced antibody adaptability may make the elderly more vulnerable to influenza

Novel ratiometric fluorescent probe for studying cellular activity of anticancer drug

Scientists uncover new mechanisms regulating neural stem cells

Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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