Cell Biology

RSS

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

When parents eat low-protein or high-fat diets it can lead to metabolic disorders in their adult offspring. Now, an international team led by researchers at the RIKEN Cluster for Pioneering Research have identified a key player and the molecular events underlying this phenomenon in mice.

19 Mar 2020

High-throughput screening of AAV vector capsid libraries reveals unexpected insights

Researchers have used high-throughput screening of adeno-associated viral (AAV) vector capsid libraries to maximize the likelihood of obtaining AAV variants with desired properties.

18 Mar 2020

Research demonstrates control mechanism of force-induced cell-to-cell attachment

Using the amphibian Xenopus laevis as a model, Drs. Noriyuki Kinoshita and Naoto Ueno from the National Institute for Basic Biology, Japan and Dr. Ileana Cristea from Princeton University, USA have demonstrated that physical forces, such as centrifugal force, enhance cell-to-cell attachment and increase the stiffness of embryonic tissues as a result of force-induced cell shape change.

18 Mar 2020

New type of artificial binding proteins for blocking sugar structures on cell surfaces

The laboratory directed by Arne Skerra, Professor of Biological Chemistry, has its focus on designing artificial binding proteins for therapeutic applications.

17 Mar 2020

Study provides new insight on neural basis of tremors

New insight on what happens in brain cells to cause tremors in mice has been published today in the open-access journal eLife.

17 Mar 2020

Changes in cellular degradation hubs can lead to cancer

A team of scientists at Uppsala University has revealed that alterations in cells’ lysosomes underly abnormal cell growth.

17 Mar 2020

Uncovering the Achilles' heel of cancer cells to find effective cures

The key to effective cures for cancers is to find weak points of cancer cells that are not found in non-cancer cells.

17 Mar 2020

Researchers elucidate new mechanism for controlling DNA methylation in cells

Why normal cells turn into cancer cells One of the factors is deeply related to the failure of the cell differentiation mechanism called DNA methylation.

17 Mar 2020

Study shows how alterations in cellular degradation hubs can lead to cancer

Cancer cells grow and divide in an uncontrolled manner. A new study from Uppsala University now shows how alterations in a cell's degradation hubs, called lysosomes, can cause abnormal cell growth.

17 Mar 2020

Chronic microfiber exposure causes aneurysms, cellular changes in fish

Chronic exposure to microplastic fibers causes aneurysms, erosion of surface layers and other serious damage to fish gills, and increases egg production in female fish, a sign that chemicals in the fibers may be acting as endocrine disruptors, a new study by U.S. and Chinese scientists finds.

16 Mar 2020

Scientists engineer silkworms to produce different variants of adhesion molecules

Silkworms are useful for more than just making strong and absorbent strings of silky thread for the textiles industry.

16 Mar 2020

Scientists find new way to amplify miRNA in live tumor cells for bioimaging

A good indicator of dysregulation in live cells is a change in their RNA expression. MicroRNA (miRNA), a special type of RNA, is considered a biomarker for carcinogenic cells.

16 Mar 2020

Research reveals how skin cells embark on a swift yet elaborate death

Skin is our body's most ardent defender against pathogens and other external threats. Its outermost layer is maintained through a remarkable transformation in which skin cells swiftly convert into squames--flat, dead cells that provide a tight seal between the living portion of the skin and the world outside.

13 Mar 2020

SPRK1 enzyme plays role in reorganizing the paternal genome during fertilization

A sperm enters an egg, an embryo develops and eventually a baby is born. But back up a second -- how does the mother's half-genome actually merge with the father's half-genome to form one new human genome?

13 Mar 2020

Blood stem cells conserve epigenetic memory of previous infections to boost immunity

These findings should have a significant impact on future vaccination strategies and pave the way for new treatments of an underperforming or over-reacting immune system. The results of this research are published in Cell Stem Cell on March 12, 2020.

13 Mar 2020

Gut microbiota generate bursts of diversity at unprecedented amounts

Scientists lead by Isabel Gordo, catch in real time the emergence of bursts of diversity in the microbiota, caused by bacterial cells with mutation rates similar to those of cancer.

12 Mar 2020

Research shows how immune cells act to limit tumor development

How does the immune system act to limit tumor development? Using in vivo imaging tools, scientists from the Institut Pasteur and Inserm described the spatiotemporal activity of tumor-infiltrating T lymphocytes, both locally and remotely.

12 Mar 2020

Understanding how cancer cells interact and collaborate to metastasize

Cancer cells are known to migrate and collaborate to form networks that function as conduits providing access to nutrients and blood vessels.

12 Mar 2020

Researchers visualize first structure of key enzyme that helps make triglycerides

The first structure of a lipin enzyme, which carries out an important step in the production of triglycerides, the main reservoir for long-term energy storage, will help scientists to better understand how lipins regulate the production of triglycerides.

11 Mar 2020

Exploiting careless cancer cells to develop new drugs

Could the ability of cancer cells to quickly alter their genome be used as a weapon against malignant tumors? Researchers at Uppsala University have succeeded in developing a substance that has demonstrated promising results in experiments on both animal models and human cancer cells.

11 Mar 2020

Cell Biology

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

High-throughput screening of AAV vector capsid libraries reveals unexpected insights

Research demonstrates control mechanism of force-induced cell-to-cell attachment

New type of artificial binding proteins for blocking sugar structures on cell surfaces

Study provides new insight on neural basis of tremors

Changes in cellular degradation hubs can lead to cancer

Uncovering the Achilles' heel of cancer cells to find effective cures

Researchers elucidate new mechanism for controlling DNA methylation in cells

Study shows how alterations in cellular degradation hubs can lead to cancer

Chronic microfiber exposure causes aneurysms, cellular changes in fish

Scientists engineer silkworms to produce different variants of adhesion molecules

Scientists find new way to amplify miRNA in live tumor cells for bioimaging

Research reveals how skin cells embark on a swift yet elaborate death

SPRK1 enzyme plays role in reorganizing the paternal genome during fertilization

Blood stem cells conserve epigenetic memory of previous infections to boost immunity

Gut microbiota generate bursts of diversity at unprecedented amounts

Research shows how immune cells act to limit tumor development

Understanding how cancer cells interact and collaborate to metastasize

Researchers visualize first structure of key enzyme that helps make triglycerides

Exploiting careless cancer cells to develop new drugs

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Latest Life Science News