Cell Biology

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Biochemical switches could be triggered to treat pathology of IBM, ALS and FTD

St. Jude Children's Research Hospital scientists have found that the enzymes ULK1 and ULK2 play a key role in breaking down cell structures called stress granules, whose persistence leads to toxic buildup of proteins that kill muscle and brain cells.

11 Apr 2019

Scientists discover central role of cell 'skeleton'

All cells possess a cytoskeleton which allows them to move and maintain their shape. However, scientists recently showed that a part of this cytoskeleton called branched actin is also essential to cell proliferation: this actin transmits information to cells about the space around them, environmental chemical messages and therefore on whether they should proliferate.

10 Apr 2019

Chinese FDA clears Cytek’s DxP Athena for clinical diagnostic use

Thirteen-color flow cytometry just became much easier for clinical flow cytometry laboratories based in China. Cytek Biosciences Inc., a leading provider of flow cytometry instrumentation, today announced that the Chinese FDA has cleared its DxP Athena flow cytometer for clinical diagnostic use in hospitals, laboratories and clinics across China.

From Cytek Biosciences 10 Apr 2019

‘Hit-and-run’ interaction between proteins appears to be key trigger for cell death

A 'hit-and-run' interaction between two proteins could be an important trigger for cell death, according to new research from Walter and Eliza Hall Institute researchers.

10 Apr 2019

New bioinformatics method helps scientists to understand differences in gene regulation in cells

A Belgian team of computational biologists led by Stein Aerts has developed a new bioinformatics method called cisTopic.

10 Apr 2019

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

The recent emergence of immunotherapy has marked a sea change in research and care for many forms of cancer, bringing new hope to patients and families around the world. For those who respond to treatment, the results can be dramatic.

10 Apr 2019

High Throughput Nucleic Acid Purification Simplified

Labs demand purity and flexibility for high throughput nucleic acid purification, while needing to complete difficult downstream analysis, for example NGS.

From Promega Corporation 9 Apr 2019

Scientists visualize immune cells fighting blood cancer for the first time

When cancer escapes the immune system, our defenses are rendered powerless and are unable to fight against the disease.

8 Apr 2019

Cellular protein could take on role of restriction factor for hepatitis B virus

Hepatitis B is a viral liver infection that can lead to acute or chronic conditions. Although there is a vaccine that offers protection against the virus, current treatments which prevent the virus from replicating are not curative for infected individuals.

8 Apr 2019

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5 in the journal Molecular Therapy.

8 Apr 2019

Scientists develop new imaging technology to visualize cells' eating habits

Scientists have developed a new imaging technology to visualize what cells eat, which could aid the diagnosis and treatment of diseases such as cancer.

8 Apr 2019

Researchers discover how specific mutation obstructs healthy blood cell maturation

In the veins, stem cells constantly mature and develop into different blood cells that are necessary for the body to work properly.

5 Apr 2019

Researchers determine atomic structure of fusion protein of a prokaryotic organism

Many viruses, including that perennial winter affliction, the influenza virus, are protected by a lipid membrane on loan from the host cell.

5 Apr 2019

Scientists use a promiscuous inhibitor to uncover cancer drug targets

Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells.

5 Apr 2019

Researchers unravel 3D structure of key molecular target for cancer treatment

Columbia University scientists, in collaboration with researchers from Nimbus Therapeutics, have demystified a metabolic enzyme that could be the next major molecular target in cancer treatment.

4 Apr 2019

New computational model of human kinase may provide insights for cancer drug development

Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human cancers.

4 Apr 2019

Salk researchers reveal new role for a driver of metastatic cancers

Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. Now, Salk Institute researchers have revealed a new role for the CDK12 protein. The findings were published in the print version of Genes & Development on April 1, 2019.

3 Apr 2019

G:BOX Chemi XX6 imager used to speed up analysis of proteins linked with breast cancer

Syngene, a world-leading manufacturer of image analysis solutions, today announced its G:BOX Chemi XX6 multi-application imager is being utilized by scientists at a major London university to speed up analysis of proteins, DNA and cells associated with breast and a range of other cancer types.

From Syngene 3 Apr 2019

Analysis of tumor microenvironment to improve effectiveness of preclinical trials

It was shown that co-culturing HeLa adenocarcinoma cells, peripheral blood mononuclear cells, and mesenchymal stromal cells results in changes in the proliferative activity of the peripheral blood mononuclear cells and mesenchymal stromal cell populations.

3 Apr 2019

Photoacoustic microscopy helps scientists to better scrutinize cancer cells

Devising the best treatment for a patient with cancer requires doctors to know something about the traits of the cancer from which the patient is suffering.

2 Apr 2019

Cell Biology

Biochemical switches could be triggered to treat pathology of IBM, ALS and FTD

Scientists discover central role of cell 'skeleton'

Chinese FDA clears Cytek’s DxP Athena for clinical diagnostic use

‘Hit-and-run’ interaction between proteins appears to be key trigger for cell death

New bioinformatics method helps scientists to understand differences in gene regulation in cells

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

High Throughput Nucleic Acid Purification Simplified

Scientists visualize immune cells fighting blood cancer for the first time

Cellular protein could take on role of restriction factor for hepatitis B virus

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

Scientists develop new imaging technology to visualize cells' eating habits

Researchers discover how specific mutation obstructs healthy blood cell maturation

Researchers determine atomic structure of fusion protein of a prokaryotic organism

Scientists use a promiscuous inhibitor to uncover cancer drug targets

Researchers unravel 3D structure of key molecular target for cancer treatment

New computational model of human kinase may provide insights for cancer drug development

Salk researchers reveal new role for a driver of metastatic cancers

G:BOX Chemi XX6 imager used to speed up analysis of proteins linked with breast cancer

Analysis of tumor microenvironment to improve effectiveness of preclinical trials

Photoacoustic microscopy helps scientists to better scrutinize cancer cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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