Cell Biology

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Researchers discover how protein pair regulates cellular calcium signals

All mammalian cells need a ready supply of calcium ions to execute functions as diverse as neurotransmission, muscle contraction, hormone release, or immune responses. So fundamental is this requirement that cells protect themselves from disaster by storing calcium in a network of intracellular cisterns called the endoplasmic reticulum, or ER.

31 Oct 2018

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

A genetic defect tied to a variety of neurodegenerative diseases and mental illnesses changes how cells starved of sugar metabolize fatty compounds known as lipids, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health shows.

31 Oct 2018

Study explores impact of new Texas law HB 810 on stem cell interventions

A new study takes a close look at the content and potential implications of the new Texas law HB 810, which aims to expand assess of experimental stem cell interventions outside the realm of clinical trials under FDA oversight.

31 Oct 2018

First shared Swiss platform to promote regenerative medicine launched in Bern

Regenerative Medicine is one of the fastest growing sectors in biomedical research – replacing diseased cells, tissues or organs.

31 Oct 2018

Study: Single protein regulates network of genes essential for sperm development

A single protein regulates a battery of key genes inside developing sperm, according to a new study out of Case Western Reserve University School of Medicine.

31 Oct 2018

Scientists describe novel conjugates made from antibodies and protein inhibitor

Linking therapeutically active molecules to specific antibodies can help to pilot them to their designated targets and minimize side effects--especially when treating tumors. In the journal Angewandte Chemie, scientists have now described novel conjugates made from antibodies and a kinesin spindle protein inhibitor.

31 Oct 2018

Individual heart cells respond differently to high blood pressure

A team of cardiologists have found that single cells within the heart are affected by high blood pressure in different ways. Some adapt, whilst others fail.

30 Oct 2018

Game-changing microscope enables UK scientists to understand amyloid structure

Scientists have used cryo-electron microscopes to generate 3D images of amyloid, showing that aggregates form long, twisted fibers.

30 Oct 2018

Groundbreaking Khíron chip enables fast, accurate intra-tissue measurement

A new gold standard for electrical measurement in the emerging in vitro world of three dimensional models. That's what Swiss medtech 3Brain has established by partnering with CSEM.

30 Oct 2018

Scientists discover cell adhesion mechanism used by mycoplasma genitalium

Researchers from the Molecular Biology Institute of Barcelona and the Institute of Biotechnology and Biomedicine have discovered the mechanism by which the bacterium Mycoplasma genitalium) adheres to human cells.

29 Oct 2018

Researchers uncover new insights on cancer growth

Walter and Eliza Hall Institute researchers have uncovered new insights into how the normal controls on cell growth are lost in cancer cells, leading to rapid tumor expansion.

29 Oct 2018

Insights into tumor initiation pave way for new skin cancer treatments

Researchers from VIB and KU Leuven uncovered a key vulnerability of melanoma. While studying the role of the melanoma-specific long non-coding RNA SAMMSON in tumor initiation, the researchers found that it boosts protein synthesis in different cellular compartments. Normal cells are alerted by modification in protein synthesis and react to this threat, but only if this process is altered in one compartment at the time.

29 Oct 2018

New method increases virus production in cells to generate more vectors for gene transfer

Researchers at Tokyo Medical and Dental University have established a method to increase the released lentiviral particles produced by host cells, which will aid the use of the vectors for introducing foreign genes into cells

29 Oct 2018

Novel bioreactor allows ultrasonic monitoring of human cartilage grown in 3D

A team of Spanish scientists has designed a bioreactor that allows to grow, in four weeks, human cartilage tissues in scaffolds generated by 3D printing.

29 Oct 2018

Scientists discover kill code in all cells that can be triggered to destroy cancer

Researchers have discovered a kill code present within every cell of the body in the form of microRNAs that can cause cancerous cells to self-destruct

29 Oct 2018

Forced expression of a natural protein reduces fat in mice by a third

In a mouse model of obesity, forced expression of the protein FGFBP3 (BP3 for short) significantly reduced the animals’ fat mass.

29 Oct 2018

Barcelona researchers win one of the most prestigious EU grants to study CLL

The European Research Council today announced the results of the 2018 Synergy Grants call for proposals. The aim of Synergy Grants is to address ambitious research questions that can only be answered by the coordinated work of a small group of two to four principal investigators and their teams, bringing together their complementary skills, knowledge and resources.

26 Oct 2018