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Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

American and British teams led by Drs Kohn (University of California, Los Angeles), Malech (NIH), Williams (Boston Children's) and Trasher (Great Ormond Street Institute of Child Health) published yesterday in Nature Medicine the conclusive results of a gene therapy trial conducted in the United States and Great Britain in 9 patients with X-linked Chronic Septic Granulomatosis (X-CGD), a rare and severe immune dysfunction. Six of them are free of treatment for complications generated by the disease.

28 Jan 2020

What parents need to know about the HPV vaccine

The vaccine that prevents infection from human papillomavirus (HPV) is nothing short of a medical marvel.

28 Jan 2020

NICU babies have higher risk of mental health problems in later life

Children who spend time in a neonatal intensive care unit at birth have a higher risk of mental health issues later, regardless of their birth weight, say McMaster University researchers.

28 Jan 2020

Study shows that children prefer to learn from confident people and can gauge if confidence is justified

A new study has found that young children prefer to learn from people they see as confident.

28 Jan 2020

Vitamin D in pregnancy reduces risk of enamel defects in offspring

An important randomized trial shows that when vitamin D is supplemented at high doses in the last three months of pregnancy, there is a fall in the occurrence of enamel defects in the deciduous (milk) and permanent teeth of the offspring by half, over the next 6 years, compared to a low dose supplementation. However, the incidence of caries was not affected.

27 Jan 2020

Preterm survival rate up by 25 percent thanks to the quality improvement program

Preterm birth occurs before 37 weeks of gestation and has been tied to many complications in the infant. In Canada, the rate of survival of very preterm infants born between 28 to 32 weeks, improved by 25 percent, thanks to the national Evidence-based Practice for Improving Quality (EPIQ) program in neonatal intensive care units (NICUs) across the country.

27 Jan 2020

Increased youth suicide rates found in high poverty communities

A study led by Jennifer Hoffmann, MD, from Ann & Robert H. Lurie Children's Hospital of Chicago, found that higher county-level poverty is associated with increased youth suicide rates among children 5-19 years old in the United States in 2007-2016.

27 Jan 2020

Climate change inflicts catastrophic effects on children’s health

The grim effects that climate change will have on pediatric health outcomes was the focus of a "Viewpoint" article published in the Journal of Clinical Investigation by Susan E. Pacheco, MD, an expert at The University of Texas Health Science Center at Houston.

27 Jan 2020

Weak evidence found on added benefit of asfotase alfa treatment for infants with hypophosphatasia

Hypophosphatasia (HPP) is a rare congenital metabolic disorder. The frequency of severe courses of disease is estimated at 1:100 000: A deficiency of the enzyme phosphatase results in insufficient mineralization of the bones and thus in severe skeletal malformations.

27 Jan 2020

Puberty blockers reduce suicidal ideations among transgender teens

Transgender teens have a higher risk of having suicidal ideations, reports the U.S. Centers for Disease Control and Prevention (CDC). A new study suggests that having access to puberty blockers can significantly reduce the risk of suicide and other mental health issues.

26 Jan 2020

Early life exposure to traffic-related air pollution may cause structural brain changes at age 12

A new study suggests that significant early childhood exposure to traffic-related air pollution (TRAP) is associated with structural changes in the brain at the age of 12.

24 Jan 2020

30-year study of MSUD highlights critical need for more effective disease-modifying therapies

A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders.

24 Jan 2020

Horseback riding along with brain-building tasks can benefit children with neurodevelopmental disorders

Therapeutic horseback riding combined with brain-building exercises can improve the dexterity, coordination and strength of children with neurodevelopmental disorders, shows a study in Frontiers in Veterinary Science.

24 Jan 2020

Healing and hope for families affected by fragile X in Eastern Europe

Mothers and fathers and their young children crowded into an old, government-run children's hospital in Belgrade, Serbia, colorful, cartoonish drawings covering its hallway walls. Parents struggled to soothe their anxious, wriggly boys and girls. But they were patient, polite. It was, after all, a day unlike any other. A day for hope.

23 Jan 2020

Implementation of combined pediatric observation unit improves patient outcomes, satisfaction

It's a quandary facing many busy emergency departments across the country: how to treat young patients who require emergency care and a brief stay while reserving limited inpatient beds for the most acute cases.

23 Jan 2020

Discovery could lead to early identification of children at high risk of future type 2 diabetes

Researchers at the University of Plymouth and Nestlé have revealed new insights into the factors that predispose children to developing type 2 diabetes in adult life.

23 Jan 2020

Skin-to-skin contact does not lead to better interaction between mother and child

Following a premature birth it is important that the parents and the infant quickly establish a good relationship.

23 Jan 2020

Adolescents with PCOS and obesity have more 'unhealthy' gut bacteria

Teens with obesity and polycystic ovary syndrome have more "unhealthy" gut bacteria suggesting the microbiome may play a role in the disorder, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

23 Jan 2020

Good sleep routine is important for children's emotional, physical, and mental health

With less than a week to go until the start of a new school year, parents are preparing themselves for the inevitable back-to-school rush. But amid the dash for backpacks, books and last-minute haircuts, children's sleep routines must also be high on the agenda if parents want to start kids off on the right foot.

23 Jan 2020

Many youth found to be living with undiagnosed Chronic Fatigue Syndrome

Most youth living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) have not been diagnosed, according to a new prevalence study from researchers at DePaul University and Ann & Robert H. Lurie Children's Hospital of Chicago, published by the journal Child & Youth Care Forum.

23 Jan 2020

Child Health News

Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

What parents need to know about the HPV vaccine

NICU babies have higher risk of mental health problems in later life

Study shows that children prefer to learn from confident people and can gauge if confidence is justified

Vitamin D in pregnancy reduces risk of enamel defects in offspring

Preterm survival rate up by 25 percent thanks to the quality improvement program

Increased youth suicide rates found in high poverty communities

Climate change inflicts catastrophic effects on children’s health

Weak evidence found on added benefit of asfotase alfa treatment for infants with hypophosphatasia

Puberty blockers reduce suicidal ideations among transgender teens

Early life exposure to traffic-related air pollution may cause structural brain changes at age 12

30-year study of MSUD highlights critical need for more effective disease-modifying therapies

Horseback riding along with brain-building tasks can benefit children with neurodevelopmental disorders

Healing and hope for families affected by fragile X in Eastern Europe

Implementation of combined pediatric observation unit improves patient outcomes, satisfaction

Discovery could lead to early identification of children at high risk of future type 2 diabetes

Skin-to-skin contact does not lead to better interaction between mother and child

Adolescents with PCOS and obesity have more 'unhealthy' gut bacteria

Good sleep routine is important for children's emotional, physical, and mental health

Many youth found to be living with undiagnosed Chronic Fatigue Syndrome

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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