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Very high dose prednisolone reasonable alternative to ACTH for children with infantile spasms

A pilot study to determine the best hormonal treatment for infantile spasms (IS) that may lead to changes in prescribing practices for hormone therapy is being presented for the first time at the American Epilepsy Society's 66th Annual Meeting in San Diego California.

4 Dec 2012

New research finds bisphenol A in fetal liver tissues

New research from the University of Michigan School of Public Health found BPA, or bisphenol A, in fetal liver tissue, demonstrating that there is considerable exposure to the chemical during pregnancy.

4 Dec 2012

Children's Hospital Los Angeles earns Top Hospital designation from Leapfrog Group

For the fourth consecutive year, Children's Hospital Los Angeles has earned the Top Hospital designation from The Leapfrog Group, which annually recognizes the best hospitals in the nation for providing the safest and highest quality health care services to patients. Children's Hospital Los Angeles is one of only 12 children's hospitals nationally to receive this honor and was the only children's hospital in California to earn the top award.

4 Dec 2012

Many physicians misinformed about initial diagnosis and treatment of epilepsy

A survey of healthcare providers concerning the initial diagnosis and treatment of epilepsy has found significant misinformation held among physicians who see children who have seizures. Many physicians surveyed are misinformed about what constitutes intractable epilepsy, when to refer their pediatric patients for surgical evaluation, and what types of seizures may be amenable to surgical intervention.

4 Dec 2012

UI researchers develop neonatal piglet model to study micronutrient deficiencies

University of Illinois researchers have developed a model that uses neonatal piglets for studying infant brain development and its effect on learning and memory. To determine if the model is nutrient-sensitive, they have done some research on the effects of iron-deficient diets.

4 Dec 2012

IPS interview examines efforts to prevent mother-to-child HIV transmission

"On World AIDS Day, the fact that the number of children newly infected with HIV continues to decline is welcome news to UNITAID, the international drug purchase facility hosted by the World Health Organization," Inter Press Service reports, adding, "But UNITAID is also well aware of how much more remains to be done for children already living with the disease."

4 Dec 2012

Childhood HIV risks becoming neglected disease as fewer children born with HIV, experts warn

"The success in reducing the number of children born with HIV is in danger of leaving children who already have the disease with poor access to treatment, experts in HIV and AIDS have warned," BMJ reports.

4 Dec 2012

Researchers identify 4 new genetic regions that influence birth weight

Researchers have identified four new genetic regions that influence birth weight, providing further evidence that genes as well as maternal nutrition are important for growth in the womb. Three of the regions are also linked to adult metabolism, helping to explain why smaller babies have higher rates of chronic diseases later in life.

4 Dec 2012

Study compares mental health-related ED visits between children with and without ASD

In the first study to compare mental health-related emergency department (ED) visits between children with and without autism spectrum disorders (ASD), researchers found that ED visits are nine times more likely to be for psychiatric reasons if a child has an ASD diagnosis.

3 Dec 2012

Childhood trauma can leave permanent epigenetic marks on DNA

Abused children are at high risk of anxiety and mood disorders, as traumatic experience induces lasting changes to their gene regulation. Scientists from the Max Planck Institute of Psychiatry in Munich have now documented for the first time that genetic variants of the FKBP5 gene can influence epigenetic alterations in this gene induced by early trauma.

3 Dec 2012

Researchers discover four new gene regions that contribute to low birth weight

An international team of genetics researchers has discovered four new gene regions that contribute to low birth weight. Three of those regions influence adult metabolism, and appear to affect longer-term outcomes such as adult height, risk of type 2 diabetes and adult blood pressure.

3 Dec 2012

Children with changes in bully genes have poor survival

In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A and ARID1B, survive only a quarter as long as patients without the changes. The discovery could eventually lead to early identification of patients with aggressive neuroblastomas who may need additional treatments.

3 Dec 2012

New psychiatric manual won't include Asperger's diagnosis, could affect treatment payments

News outlets covered the Saturday meeting of the American Psychiatric Association as changes were approved to its manual of mental disorders.

2 Dec 2012

Controlling weight during pregnancy benefits both mothers and their babies

Two-thirds of Australian mums-to-be are in the dark when it comes to how much weight they should gain during pregnancy.

1 Dec 2012

New genetic study defines biology behind brain developmental disorder in children

This study describes how a combination of sequencing and mouse models were used to identify the gene responsible for a brain developmental disorder seen in four patients.

1 Dec 2012

TEMPEST research project can help children resist temptations to unhealthy snacks

Children and young people in Europe are exposed to all kinds of fast food, crisps and fizzy drinks - so how can they learn to resist the temptation to indulge? This is the question that the European research project TEMPEST was set up to answer. The research project involves researchers from nine European countries and one of the team members is Liliya Nureeva, a PhD student at Aarhus University.

1 Dec 2012

CINJ experts available to comment on importance and uses of blood donations

Every two seconds, someone in the United States is in need of blood. According to the American Red Cross, more than 44,000 blood donations are needed each day. With just one donation of a pint of blood, up to three lives can be saved. Nationally, less than 38 percent of the population is eligible to give blood. In New Jersey, according to the state Department of Health fewer than four percent of eligible residents donate regularly, resulting in the critical need for blood donations.

30 Nov 2012

NAP and SAL injection during pregnancy improve memory, learning tasks in offsprings

Mice with a condition that serves as a laboratory model for Down syndrome perform better on memory and learning tasks as adults if they were treated before birth with neuroprotective peptides, according to researchers at the National Institutes of Health.

30 Nov 2012

Special issue of Disease Markers explores ASD genetics and biomarker development

Autism spectrum disorders (ASD) are neurodevelopmental disorders typically characterized by difficulties in social interactions and delayed or abnormal language development. Although ASD reportedly affects 1 in 88 people in the United States, to date there have been no distinctive biomarkers to diagnose the disease.

30 Nov 2012

Children's Medical Center NICU receives Level IV designation

The Neonatal Intensive Care Unit (NICU) at Children's Medical Center has been designated a Level IV NICU, the highest qualification for such programs, as established by the American Academy of Pediatrics under newly revised standards.

30 Nov 2012

Child Health News

Very high dose prednisolone reasonable alternative to ACTH for children with infantile spasms

New research finds bisphenol A in fetal liver tissues

Children's Hospital Los Angeles earns Top Hospital designation from Leapfrog Group

Many physicians misinformed about initial diagnosis and treatment of epilepsy

UI researchers develop neonatal piglet model to study micronutrient deficiencies

IPS interview examines efforts to prevent mother-to-child HIV transmission

Childhood HIV risks becoming neglected disease as fewer children born with HIV, experts warn

Researchers identify 4 new genetic regions that influence birth weight

Study compares mental health-related ED visits between children with and without ASD

Childhood trauma can leave permanent epigenetic marks on DNA

Researchers discover four new gene regions that contribute to low birth weight

Children with changes in bully genes have poor survival

New psychiatric manual won't include Asperger's diagnosis, could affect treatment payments

Controlling weight during pregnancy benefits both mothers and their babies

New genetic study defines biology behind brain developmental disorder in children

TEMPEST research project can help children resist temptations to unhealthy snacks

CINJ experts available to comment on importance and uses of blood donations

NAP and SAL injection during pregnancy improve memory, learning tasks in offsprings

Special issue of Disease Markers explores ASD genetics and biomarker development

Children's Medical Center NICU receives Level IV designation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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