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De novo somatic gene mutations likely to cause hemimegalencephaly

Hemimegalencephaly is a rare but dramatic condition in which the brain grows asymmetrically, with one hemisphere becoming massively enlarged. Though frequently diagnosed in children with severe epilepsy, the cause of hemimegalencephaly is unknown and current treatment is radical: surgical removal of some or all of the diseased half of the brain.

25 Jun 2012

Smoking of fathers before conception can damage genetic information of their offspring

As you decide what to get dad for Father's Day, you might want to consider what he gave you when you were conceived. If he smoked, your genes are likely damaged, and your odds for cancers and other diseases throughout your life could be increased. A new research report appearing online in the FASEB Journal, scientists show for the first time in humans that men who smoke before conception can damage the genetic information of their offspring.

23 Jun 2012

GlobalPost blog series examines PMTCT program in South Africa

In the third of a series of entries in GlobalPost's "Global Pulse" blog, titled "A Daughter's Journey," Tracy Jarrett, a GlobalPost/Kaiser Family Foundation global health reporting fellow, visits a USAID-funded HIV clinic at the Chris Hani Baragwanath Hospital outside of Johannesburg, South Africa.

23 Jun 2012

Study reveals decline in number of babies born with birth defects across Europe

The number of babies born with birth defects (major congenital anomalies) across Europe has fallen over the decade (2000-2009), University of Ulster research has revealed.

23 Jun 2012

Alcohol during pregnancy can be harmful for the developing baby

Experts at the University of California, San Diego School of Medicine disagree with a series of new studies from Denmark that suggest consumption of up to 8 alcoholic drinks a week or occasional binge drinking during pregnancy is generally safe for the developing baby.

23 Jun 2012

Ten-year-old kid to participate in annual Arthritis Walk on June 23

Ten-year-old Cheyanne Campo has achieved a lofty goal, despite - and because of - a sometimes painful disease. She has raised more than $500 for the Arthritis Foundation and will be participating in the organization's annual Arthritis Walk on June 23 in Battery Park.

23 Jun 2012

Young children have higher prevalence of mental health problems: Study

A study published in the June 2012 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that young children who have been investigated for maltreatment by child welfare agencies have a higher prevalence of mental health problems and that very few receive treatment for those problems.

23 Jun 2012

Parents play a major role in children's TV time

Researchers at Oregon State University have confirmed what we knew all along - children in this country are increasingly sedentary, spending too much time sitting and looking at electronic screens.

22 Jun 2012

Global initiative to improve quality of midwifery care

Researchers from across the world have joined forces to improve the quality of midwifery care and reduce maternal, newborn and infant mortality.

22 Jun 2012

Researchers identify genes that cooperate in development of medulloblastoma

St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project lifts lid on the most aggressive subtype of medulloblastoma and finds genes that cooperate in tumor development.

22 Jun 2012

Addressing the need for a new global roadmap for reducing child mortality

"In mid-June, representatives of 80 governments, the private sector, NGOs, civil society and faith-based organizations met to launch the Child Survival Call to Action: a sustained, global effort to lower child mortality rates, especially in high-risk countries," a VOA editorial reports.

22 Jun 2012

Protein in blood can predict improper growth of fetus

Researchers from the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa) have found a protein in the blood of pregnant women that can predict if they are likely to have a fetus that doesn't grow properly, and thus has a high risk of stillbirth and long-term health complications.

22 Jun 2012

Parents must be considered during expansion of genetic screening programs for newborns

Parents must be considered when states decide to expand genetic screening programs for newborns, according to a new study that looked at mandatory testing panels and political pressure by advocacy groups.

22 Jun 2012

Sanford Health CAO receives NOFAS Excellence Award for commitment to FAS

H. Eugene Hoyme, MD, chief academic officer for Sanford Health and president of Sanford , has received the 2012 Excellence Award from the National Organization on Fetal Alcohol Syndrome (NOFAS), joining the ranks of almost 40 past recipients that include Senator John McCain and the late Ted Kennedy.

22 Jun 2012

U.N. agencies renew commitment to REACH initiative to combat child hunger, malnutrition

"United Nations agencies on Wednesday stressed the need to tackle child hunger and undernutrition in the pursuit of sustainable development, highlighting a joint initiative that offers practical and effective approaches to combat this problem in the most affected countries," the U.N. News Centre reports.

22 Jun 2012

Moderate alcohol intake during pregnancy does not influence child's development and intelligence

Children born by mothers who have of consumed between 1 and 6 alcohol units per week are just as intelligent and well-developed as children of abstaining mothers. Mothers who have been drinking 5 or more drinks on a single occasion a limited number of times before realizing that they were pregnant may also breathe a sigh of relief; their children have not been harmed.

22 Jun 2012

Aeterna Zentaris announces perifosine Phase 1 trial on neuroblastoma

Aeterna Zentaris Inc. today announced that Phase 1 trial results for its oral PI3K/Akt inhibitor, perifosine, showed the drug's activity against chemo-resistant and radio-resistant neuroblastoma, while allowing good quality of life and sparing vital organs. Neuroblastoma is a type of childhood cancer which usually begins in nerve tissues.

22 Jun 2012

Report: Autoimmune diseases are all being diagnosed at rapid rates

There is a disturbing trend in autoimmune disease diagnosis; many are on the upswing. Recent reports show that type 1 diabetes (an autoimmune disease not related to obesity), celiac disease and lupus, among others autoimmune diseases, are all being diagnosed at rapid rates.

22 Jun 2012

Polio eradication efforts threatened by funding shortfall, vaccination resistance in some countries, experts say

Marking the 10th anniversary since Europe was declared polio-free, the Independent Monitoring Board (IMB) of the Global Polio Eradication Initiative on Wednesday released a report saying there is "a unique window of opportunity to stamp out polio for good," with the number of reported cases at historical lows, but a funding shortfall of about $1 million is threatening eradication progress, Reuters reports.

22 Jun 2012

Lead 8A analog can treat osteosarcoma in children

Jiayuh Lin, PhD, and colleagues at Nationwide Children's Hospital have developed a drug to target the most common cancerous bone tumor in children, osteosarcoma, using a version of the FDA-approved drug, Celebrex. The team will soon begin testing the drug using human and canine tumor cell lines thanks to a two-year, $200,000 grant from Alex's Lemonade Stand Foundation for Childhood Cancer.

22 Jun 2012