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TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Tuberculosis has been infecting humans for several millennia, making it one of the most horribly successful diseases in history. Today, it is still a major killer, responsible for some 1.5 million deaths each year.

18 Nov 2015

Coating implants with certain 'activator' can prevent S. aureus infection

Biofilms frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can cause life-threatening infections. New research at the Sahlgrenska Academy show that coating implants with a certain "activator" can prevent Staphylococcus aureus, the leading cause of hospital-acquired infections, from forming biofilms.

18 Nov 2015

TSRI researchers have new weapons to combat HIV

Scientists at The Scripps Research Institute have new weapons in the fight against HIV. Their new study, published November 17, 2015 as the cover article of the journal Immunity, describes four prototype antibodies that target a specific weak spot on the virus. Guided by these antibodies, the researchers then mimicked the molecular structure of a protein on HIV when designing their own potential HIV vaccine candidate.

18 Nov 2015

First patient enrolled in Phase 2 clinical trial of Immune's bertilimumab in Ulcerative Colitis

Immune Pharmaceuticals Inc. announced today that the first patient has been enrolled into the Phase 2 clinical trial evaluating the safety and efficacy of its first in class fully human monoclonal antibody, bertilimumab in Ulcerative Colitis (UC).

17 Nov 2015

Positive data from AbbVie's HCV clinical development program presented at The Liver Meeting of AASLD

AbbVie, a global biopharmaceutical company, today announced data from the SURVEYOR studies of its investigational HCV regimen, ABT-493, an NS3/4A protease inhibitor, and ABT-530, an NS5A inhibitor, that show high rates of sustained virologic response at 12 weeks post-treatment (SVR 12) in non-cirrhotic patients with chronic hepatitis C virus (HCV) infection.

17 Nov 2015

People confused about antibiotic resistance, shows WHO survey

As the World Health Organization ramps up its fight against antibiotic resistance, a new multi-country survey shows people are confused about this major threat to public health and do not understand how to prevent it from growing.

17 Nov 2015

Archbishop of York agrees to become Antibiotic Research UK's Patron

Antibiotic Research UK, a charity founded in 2014 to save modern medicine from the onslaught of superbugs, is delighted to announce that the Most Reverend & Right Honourable Dr John Sentamu, Archbishop of York has agreed to become the Charity’s Patron.

17 Nov 2015

Nearly 50% of Medicaid patients infected with hepatitis C denied coverage for life-saving antiviral drugs

Nearly 50 percent of Medicaid patients infected with chronic hepatitis C whose doctors had prescribed newer, life-saving antiviral drugs were denied coverage to the therapies because they weren't considered "a medical necessity" or because the patients tested positive for alcohol/drugs, among other reasons, according to new Penn Medicine research.

17 Nov 2015

Study shows how parasitic worm infection increases susceptibility to TB

Scientists have shown how a parasitic worm infection common in the developing world increases susceptibility to tuberculosis. The study demonstrated that treating the parasite reduces lung damage seen in mice that also are infected with tuberculosis, thereby eliminating the vulnerability to tuberculosis (TB) that the parasite is known to cause.

17 Nov 2015

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Researchers from the University of Birmingham have, for the first time, identified how Salmonella infections that have spread to our blood and organs can lead to life-threatening thrombosis.

17 Nov 2015

Study: Safe spaces may play critical role in community-based HIV prevention efforts

The creation and sustainment of "safe spaces" may play a critical role in community-based HIV prevention efforts by providing social support and reducing environmental barriers for vulnerable populations, a new study from an Oregon State University researcher has found.

17 Nov 2015

New US bipartisan study advocates promoting global health to advance wide range of American interests

A new US bipartisan study advocates promoting global health to both "do the right thing" and advance wide-ranging foreign policy interests.

17 Nov 2015

ESCMID takes vital steps in fight against antimicrobial resistance

The European Society of Clinical Microbiology and Infectious Disease – an organization that explores the risks and best practices in infectious disease – takes the opportunity ahead of the European Antibiotic Awareness Day on 18 November to highlight two of the society’s more recent projects in the fight against antimicrobial resistance.

17 Nov 2015

New cancer control interventions may decrease cancer burden in low- and middle-income countries

In low-income and middle-income countries (LMICs), where 5.5 million of the world’s 8 million cancer deaths occur each year, most people with cancer have little or no access to treatment and many die in severe pain for lack of inexpensive opioid pain medicine.

17 Nov 2015

FDA finalizes innovative food safety rules to prevent foodborne illness

The U.S. Food and Drug Administration today took major steps to prevent foodborne illness by finalizing rules implementing the bipartisan Food Safety Modernization Act that, for the first time, establish enforceable safety standards for produce farms and make importers accountable for verifying that imported food meets U.S. safety standards.

15 Nov 2015

UC Irvine Health researchers develop one-step test to detect HCV infections

UC Irvine Health researchers have developed a cost-effective one-step test that screens, detects and confirms hepatitis C virus (HCV) infections. Dr. Ke-Qin Hu, director of hepatology services, will present findings at the Annual Meeting of American Association for the Study of Liver Disease in San Francisco, Nov. 14-16. Current blood-based HCV testing requires two steps and can be expensive, inconvenient and is not widely available or affordable globally.

15 Nov 2015

Analyzing potential TB vaccine

When results from a landmark tuberculosis vaccine trial in Cape Town, South Africa were published in The Lancet in February 2013, the headlines were grim, despite hopes that the trial would point toward a successful way to thwart one of the globe's biggest public health threats.

13 Nov 2015

Less effective drugs can help beat malaria more effectively

Oxford University scientists have found that the more effective way to beat malaria is to use less effective drugs some of the time.

13 Nov 2015

Researchers to develop high-precision computer models that can predict epidemic risk

Software “agents” modelled on real-life individuals will be used by University of Sydney researchers to develop high-precision computer models that can predict where or when an epidemic may strike.

13 Nov 2015

FixHepC Buyers Club exposes weakness in Australian healthcare, assists patients to import life saving medication

In one of the greatest advances in medicine in decades, Hepatitis C is now largely curable. Over 200,000 Australians suffer from Hepatitis C. However the US manufacturer, Gilead Sciences Inc is attempting to charge the PBS $84,000 for a 12 week course of medication that costs under $200 dollars to manufacture.

13 Nov 2015

Disease/Infection News

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Coating implants with certain 'activator' can prevent S. aureus infection

TSRI researchers have new weapons to combat HIV

First patient enrolled in Phase 2 clinical trial of Immune's bertilimumab in Ulcerative Colitis

Positive data from AbbVie's HCV clinical development program presented at The Liver Meeting of AASLD

People confused about antibiotic resistance, shows WHO survey

Archbishop of York agrees to become Antibiotic Research UK's Patron

Nearly 50% of Medicaid patients infected with hepatitis C denied coverage for life-saving antiviral drugs

Study shows how parasitic worm infection increases susceptibility to TB

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Study: Safe spaces may play critical role in community-based HIV prevention efforts

New US bipartisan study advocates promoting global health to advance wide range of American interests

ESCMID takes vital steps in fight against antimicrobial resistance

New cancer control interventions may decrease cancer burden in low- and middle-income countries

FDA finalizes innovative food safety rules to prevent foodborne illness

UC Irvine Health researchers develop one-step test to detect HCV infections

Analyzing potential TB vaccine

Less effective drugs can help beat malaria more effectively

Researchers to develop high-precision computer models that can predict epidemic risk

FixHepC Buyers Club exposes weakness in Australian healthcare, assists patients to import life saving medication

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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