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DS Biopharma reports completion of DS102 Phase I trial for treatment of fatty liver disorders

DS Biopharma, a privately held biopharmaceutical company, today announced the successful completion of a Phase I trial with an oral formulation of the active pharmaceutical ingredient DS102 (15-HEPE) which is being explored for the treatment of fatty liver disorders, such as non-alcoholic steatohepatitis (NASH) and pulmonary disorders, such as idiopathic pulmonary fibrosis (IPF).

18 Dec 2015

New vaccine shows promise against Middle East respiratory syndrome in dromedary camels

An international research project with the involvement of Universitat Autònoma de Barcelona and the Animal Health Research Centre (IRTA-CReSA), has designed a vaccine shown to be effective in protecting dromedaries against the coronavirus (CoV) that causes Middle East respiratory syndrome (MERS).

18 Dec 2015

MPP signs licensing agreement with AbbVie to address future demands for HIV treatment in Africa

The Medicines Patent Pool today announced a new licensing agreement with AbbVie, a global biopharmaceutical company, that seeks to address future demands for HIV treatment Lopinavir/Ritonavir (LPV/r) in South Africa and across Africa. The agreement has been reached in particular to help ensure sustainability of long-term supply of LPV/r, the most widely used second-line HIV treatment in South Africa and across Africa.

18 Dec 2015

Findings show promising evidence for creating broad-spectrum antiviral

UW researchers working in collaboration with Kineta Inc. and the University of Texas at Galveston have shown that making a drug-like molecule to turn on innate immunity can induce genes to control infection in several -known viruses.

18 Dec 2015

New discovery could open door to potential treatment for West Nile virus and Dengue virus infections

A new discovery from the University of Alberta's Faculty of Medicine & Dentistry could open the door to one day treat or prevent diseases caused by West Nile virus and Dengue virus infections.

18 Dec 2015

More effort needed to reduce risks of mosquito-transmitted epidemics in the U.S. and Mexico

Despite the increasing risks of mosquito-transmitted epidemics in the United States and Mexico, policymakers in both countries have made little effort to prevent future outbreaks, according to a new policy brief by tropical-disease and science policy experts at Rice University's Baker Institute for Public Policy.

18 Dec 2015

Study examines effect of nonoperative treatment for appendicitis

It is too early to change the standard treatment of appendicitis in U.S. adults to initial antibiotic therapy only, rather than surgical removal of the appendix, or appendectomy, authors of a new systematic review study conclude.

18 Dec 2015

Hospital-acquired infections prevention market in the U.S. to grow at CAGR of over 7% during 2015 - 2020

According to recently published Pharmaion report, "United States Hospital-acquired Infections Prevention Market Opportunities, 2010 - 2020", hospital-acquired infections prevention market in the United States is projected to grow at a CAGR of over 7% during 2015 - 2020.

17 Dec 2015

Candidiasis needs to be treated early, aggressively to help vulnerable hospitalized patients

One of the most common causes of healthcare-associated infections, candidiasis is a serious, life-threatening fungal infection that needs to be treated early, aggressively and appropriately, note updated guidelines released by the Infectious Diseases Society of America and published in the journal Clinical Infectious Diseases.

17 Dec 2015

New paper outlines strategies to address hepatitis C in incarcerated individuals

More than one in nine people with hepatitis C in Canada spend time in a correctional facility each year and researchers said this presents a unique opportunity to focus hepatitis C prevention and control efforts in incarcerated populations.

17 Dec 2015

RBHS Chancellor leads study to eliminate chronic viral hepatitis

Chronic viral hepatitis has a reputation for being a silent killer. The infection often goes undetected until the symptoms of advanced liver cancer appear. By that point, a patient has a five-year survival rate, according to the American Cancer Society.

17 Dec 2015

Louisville researchers move closer to potential treatment for gum disease

University of Louisville researchers recently received a patent on a synthetic biochemical compound and its variants, moving science closer to a treatment for gum disease. This discovery could lead to the formulation of a mouth rinse or tooth varnish to prevent the pathogen, P. gingivalis from colonizing in the mouth and establishing itself orally.

17 Dec 2015

UMMS researchers identify new life cycle stage in HIV infection

Researchers at the University of Massachusetts Medical School have identified a new life cycle stage in HIV infection, thanks to a novel technique they developed to take images of intact infected cells.

17 Dec 2015

Scientists reveal major players in severe muscle damage caused by sepsis

Scientists from the Institut Pasteur, Paris Descartes University, Sainte-Anne Hospital and the CNRS have recently published a paper in Nature Communications in which they reveal major players in the severe muscle damage caused by sepsis, or septicemia, which explains why many patients suffer debilitating muscle impairment long-term after recovery.

17 Dec 2015

AGA issues six new clinical practice guidelines

In 2015, the American Gastroenterological Association issued six clinical practice guidelines, all published in AGA's official journal Gastroenterology, offering current, evidence-based point-of-care recommendations to guide physicians at the bedside.

17 Dec 2015

New funding supports research on new and improved drug treatments for tuberculosis, malaria

University of Toronto and McGill University scientists are leading an international partnership to discover new and improved drug treatments for tuberculosis, malaria and neglected tropical diseases -- thanks to a contribution from Merck Canada Inc., as well as an additional $5 million supplement to a grant from the Bill & Melinda Gates Foundation.

17 Dec 2015

Researchers report development of rapid, low-cost test for detecting TB in resource-limited areas

Tuberculosis (TB) is a highly infectious disease and a major global health problem, especially in countries with developing health care systems. Because there is no fast, easy way to detect TB, the deadly infection can spread quickly through communities. Now, a team reports in ACS Sensors the development of a rapid, sensitive and low-cost method for detecting the disease in resource-limited areas.

17 Dec 2015

Researchers identify how immune cells triggered by recurrent Strep A infections affect the brain

Researchers have discovered how immune cells triggered by recurrent Strep A infections enter the brain, causing inflammation that may lead to autoimmune neuropsychiatric disorders in children.

16 Dec 2015

Simple diagnostic test can help fight deadly sleeping sickness

Scientists have developed a quick and simple diagnosis method, similar to a dipstick pregnancy test, to fight a deadly sleeping sickness.

16 Dec 2015

TSRI scientists track how HIV-fighting antibodies develop over time

In a new study, a team led by scientists at The Scripps Research Institute tracked how a family of these HIV-fighting antibodies develops over time. The research shows how a future vaccine might trigger the immune system to produce these antibodies more effectively.

16 Dec 2015

Disease/Infection News

DS Biopharma reports completion of DS102 Phase I trial for treatment of fatty liver disorders

New vaccine shows promise against Middle East respiratory syndrome in dromedary camels

MPP signs licensing agreement with AbbVie to address future demands for HIV treatment in Africa

Findings show promising evidence for creating broad-spectrum antiviral

New discovery could open door to potential treatment for West Nile virus and Dengue virus infections

More effort needed to reduce risks of mosquito-transmitted epidemics in the U.S. and Mexico

Study examines effect of nonoperative treatment for appendicitis

Hospital-acquired infections prevention market in the U.S. to grow at CAGR of over 7% during 2015 - 2020

Candidiasis needs to be treated early, aggressively to help vulnerable hospitalized patients

New paper outlines strategies to address hepatitis C in incarcerated individuals

RBHS Chancellor leads study to eliminate chronic viral hepatitis

Louisville researchers move closer to potential treatment for gum disease

UMMS researchers identify new life cycle stage in HIV infection

Scientists reveal major players in severe muscle damage caused by sepsis

AGA issues six new clinical practice guidelines

New funding supports research on new and improved drug treatments for tuberculosis, malaria

Researchers report development of rapid, low-cost test for detecting TB in resource-limited areas

Researchers identify how immune cells triggered by recurrent Strep A infections affect the brain

Simple diagnostic test can help fight deadly sleeping sickness

TSRI scientists track how HIV-fighting antibodies develop over time

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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