Disease/Infection News

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New approach could help identify novel drug targets to combat lethal fungal infections

By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there are a limited number of anti-fungal agents.

6 Apr 2015

Case Western Reserve researchers explore ways to treat, cure TB

After discovering a unique group of people resistant to tuberculosis (TB) infection, Case Western Reserve researchers are leading an international team dedicated to understanding exactly how they fight off a disease that claims 1.5 million lives each year.

6 Apr 2015

Dartmouth researchers use new strategies to target drug-resistant pathogens

By engineering antibacterial enzymes, Dartmouth investigators led by Karl Griswold, PhD are using novel strategies to target the prevalent drug-resistant bacterium Staphylococcus aureus.

3 Apr 2015

Novel biosensing platform could remotely determine treatment options for HIV, E-coli

In much the same way that glucometers and pregnancy tests have revolutionized in-home diagnostic testing, researchers from Florida Atlantic University and collaborators have identified a new biosensing platform that could be used to remotely detect and determine treatment options for HIV, E-coli, Staphylococcus aureas and other bacteria.

3 Apr 2015

Study identifies single test that can predict onset of myopia in children

A study of 4,500 U.S. children over 20 years has identified a single test that can predict which kids will become nearsighted by the eighth grade: a measure of their current refractive error.

3 Apr 2015

International travelers bring multidrug-resistant shigellosis to the US

International travelers are bringing a multidrug-resistant intestinal illness to the United States and spreading it to others who have not traveled, according to a report released today by the Centers for Disease Control and Prevention (CDC).

3 Apr 2015

Microbes go dormant in the presence of SSV9 virus

The microbes could surrender to the harmless virus, but instead freeze in place, dormant, waiting for their potential predator to go away, according to a recent study in mBio.

3 Apr 2015

MRSA bacteria exposed to cigarette smoke become more resistant to antimicrobial peptides

Methicillin-resistant Staphylococcus aureus (MRSA), an antibiotic-resistant superbug, can cause life-threatening skin, bloodstream and surgical site infections or pneumonia. Researchers at the University of California, San Diego School of Medicine now report that cigarette smoke may make matters worse.

3 Apr 2015

HPAI H5 viruses of Eurasian origin continue to circulate in North American wild birds

Highly pathogenic avian influenza (HPAI) H5 viruses of Eurasian origin continue to circulate and evolve in North American wild birds.

2 Apr 2015

Collaboration between nurses and physicians decreases rates of HAIs in critical care

Collaborative relationships between nurses and physicians decrease rates of healthcare-associated infections (HAIs) in critical care, according to an article in the April issue of Critical Care Nurse.

2 Apr 2015

Treating common gum disease in CKD patients could reduce heart disease risk

Treating a common gum condition in chronic kidney disease (CKD) patients could significantly reduce their risk of potentially fatal heart disease, Aston University researchers say.

2 Apr 2015

VSV-based vaccine yields promising results for rapid development of effective Ebola vaccine

A live vaccine based on the "Vesicular Stomatitis Virus" (VSV) has yielded highly promising results for the rapid development of an effective vaccine against the Ebola virus. This vaccine would only need to be injected once for long-lasting immunoprotection.

2 Apr 2015

International researchers examine efficacy of rVSV-ZEBOV-GP Ebola vaccine

The World Health Organisation declared the Ebola virus outbreak a public health emergency in August 2014; since then the development of vaccines against Ebola virus has been fast tracked.

2 Apr 2015

Purdue researchers identify new class of chemical insecticides to control mosquitoes

Purdue researchers have identified a new class of chemical insecticides that could provide a safer, more selective means of controlling mosquitoes that transmit key infectious diseases such as dengue, yellow fever and elephantiasis.

2 Apr 2015

Hospitals, health systems preparing to treat patients with Ebola face unexpected challenges

Hospitals and health systems preparing for and treating patients with Ebola Virus Disease (EVD) in the fall of 2015 faced unexpected challenges for ensuring safety of staff, patients and the community. The experiences are detailed in two studies published online in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

2 Apr 2015

Canada's VSV-EBOV Ebola vaccine proves safe, effective in Phase 1 clinical trial

The Honourable Rona Ambrose, Minister of Health, and Canada's Chief Public Health Officer, Dr. Gregory Taylor, today welcomed the news of promising trial outcomes of Canada's VSV-EBOV Ebola vaccine. The results of several studies and trials bring the world closer to ending this global outbreak through the provision of a commercially available vaccine.

2 Apr 2015

American scientists develop simple system to detect influenza virus from nasal or throat swabs

Almost every winter sees a new wave of influenza, threatening people by its highly contagious character and severe pathogenesis if those with weak or compromised immune system are infected. But when do sniffing and high temperature only point to a bad cold and when is it real influenza? American scientists have developed a simple system for testing for the influenza virus by just taking nasal or throat swabs and measuring the viral presence amperometrically by assessing the glucose level.

2 Apr 2015

NIH approves $6.6 million in funding for Phase 2a adult eradication study of Argos' AGS-004

Argos Therapeutics, Inc., a biopharmaceutical company focused on the development and commercialization of fully personalized immunotherapies for the treatment of cancer and infectious diseases based on the Arcelis technology platform, today announced that the NIH Division of AIDS (DAIDS) has approved $6.6 million in funding for an investigator-initiated Phase 2a adult eradication study of AGS-004, the company’s investigational fully personalized immunotherapy for HIV.

2 Apr 2015

Low doses of imatinib drug can push immune system to combat bacterial infections

Low doses of the anti-cancer drug imatinib can spur the bone marrow to produce more innate immune cells to fight against bacterial infections, Emory researchers have found.

1 Apr 2015

World-first human clinical trials for Hendra virus to begin this month

An antibody manufactured at The University of Queensland will be used in world-first human Hendra virus clinical trials starting this month.

1 Apr 2015

Disease/Infection News

New approach could help identify novel drug targets to combat lethal fungal infections

Case Western Reserve researchers explore ways to treat, cure TB

Dartmouth researchers use new strategies to target drug-resistant pathogens

Novel biosensing platform could remotely determine treatment options for HIV, E-coli

Study identifies single test that can predict onset of myopia in children

International travelers bring multidrug-resistant shigellosis to the US

Microbes go dormant in the presence of SSV9 virus

MRSA bacteria exposed to cigarette smoke become more resistant to antimicrobial peptides

HPAI H5 viruses of Eurasian origin continue to circulate in North American wild birds

Collaboration between nurses and physicians decreases rates of HAIs in critical care

Treating common gum disease in CKD patients could reduce heart disease risk

VSV-based vaccine yields promising results for rapid development of effective Ebola vaccine

International researchers examine efficacy of rVSV-ZEBOV-GP Ebola vaccine

Purdue researchers identify new class of chemical insecticides to control mosquitoes

Hospitals, health systems preparing to treat patients with Ebola face unexpected challenges

Canada's VSV-EBOV Ebola vaccine proves safe, effective in Phase 1 clinical trial

American scientists develop simple system to detect influenza virus from nasal or throat swabs

NIH approves $6.6 million in funding for Phase 2a adult eradication study of Argos' AGS-004

Low doses of imatinib drug can push immune system to combat bacterial infections

World-first human clinical trials for Hendra virus to begin this month

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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