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Study brings effective hepatitis C cure closer to reality

Scientists at The Scripps Research Institute have determined the most detailed picture yet of a crucial part of the hepatitis C virus, which the virus uses to infect liver cells. The new data reveal unexpected structural features of this protein and should greatly speed efforts to make an effective hepatitis C vaccine.

29 Nov 2013

Scientists design small synthetic molecules capable of blocking AIDS virus replication

A multidisciplinary team of scientists from Spanish universities and research centres, among which is the University of Valencia, has managed to design small synthetic molecules capable of joining to the genetic material of the AIDS virus and blocking its replication.

28 Nov 2013

Medical Research Council should do more in the development of gold standard for clinical trial design

More should be done to celebrate the role of one of Britain’s leading institutions, the Medical Research Council, in the development of the gold standard for clinical trial design. Sir Iain Chalmers, writing in the Journal of the Royal Society of Medicine, questions the apparent reluctance of the MRC to take credit for its ground-breaking work in the design and management of randomised multicentre controlled clinical trials in the 1950s.

28 Nov 2013

Scientists identify new approach to fight malaria parasites

Using advanced methodologies that pit drug compounds against specific types of malaria parasite cells, an international team of scientists, including researchers at the University of California, San Diego School of Medicine and the Genomics Institute of the Novartis Research Foundation, have identified a potential new weapon and approach for attacking the parasites that cause malaria.

28 Nov 2013

Pediatric dermatologists offer tips for treating skin ailments

As parents across the Chicago area prepare to take that perfect holiday photo to send to family and friends, they may want to consider more than just getting their kids to smile and look at the camera.

28 Nov 2013

PLOS and DNDi to launch collection of neglected tropical diseases at 10-year anniversary of DNDi

As part of a collaborative initiative, PLOS and the Drugs for Neglected Diseases initiative (DNDi) are delighted to be launching a special Collection-PLOS & DNDi: a decade of Open Access and Neglected Tropical Diseases R&D (Research and Development)-to coincide with a joint event at the Institut Pasteur in Paris celebrating the 10-year anniversary of DNDi.

28 Nov 2013

Researchers identify protein in malaria that is inhibited by newly discovered anti-malarial compounds

Researchers have identified the protein in malaria-causing Plasmodium parasites that is inhibited by a newly discovered class of anti-malarial compounds known as imidazopyrazines.

28 Nov 2013

Findings highlight possible new approach to combat malaria

An international team of scientists, including researchers at Columbia University Medical Center, has identified a key metabolic enzyme that common malaria parasites require for survival at each stage of infection in humans. The findings raise the possibility of a new approach to combating malaria, one of the world's deadliest diseases. The study was published today in the online edition of the journal Nature.

27 Nov 2013

New NIH guidelines for managing opportunistic infections in children with HIV

Sharon Nachman, MD, a pediatric HIV and infectious diseases specialist at Stony Brook Children's Hospital, is a co-author of new National Institutes of Health (NIH)-issued guidelines for the prevention, treatment and management of opportunistic infections in HIV-exposed and HIV-infected children. The 2013 guidelines shed light on the most effective way to treat dangerous and deadly infections such as pneumonia or tuberculosis that can strike immunosuppressed pediatric HIV patients.

27 Nov 2013

HIV test for new inmates may not yield new diagnoses, says study

More than 90 percent of HIV-infected inmates entering prison in North Carolina had previously tested positive for the virus, according to a study published in the November 27 issue of the Journal of the American Medical Association.

27 Nov 2013

Study highlights unique barriers for African Americans with hypertension

For African-Americans who have hypertension, controlling their high blood pressure is critical to avoid serious complications. However, a history of racial discrimination and/or mistrust in their physicians often causes them to skip taking their necessary medication, finds a new study in the American Journal of Public Health.

27 Nov 2013

European research project examines toxicity factor to fight AIDS

December 1st is the annual World AIDS Day, a perfect opportunity to look at how medical research is progressing to fight the disease.

27 Nov 2013

University of Wisconsin Hospital and Clinics recognized with 2013 Partnership in Prevention Award

The U.S. Department of Health and Human Services (HHS), the Association for Professionals in Infection Control and Epidemiology (APIC), and the Society for Healthcare Epidemiology of America (SHEA) today recognized the University of Wisconsin Hospital and Clinics (UWHC) with the 2013 Partnership in Prevention Award for achieving sustainable improvements towards eliminating healthcare-associated infections (HAIs).

27 Nov 2013

Nonabsorbable antibiotics effective in eradicating CRE colonization

Orally administered, nonabsorbable antibiotics were effective in eradicating carbapenem-resistant Enterobacteriaceae (CRE) colonization, according to a new study published in the December issue of the American Journal of Infection Control, a publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

27 Nov 2013

Study shows most corneal transplants have remarkable longevity regardless of donor age

Ten years after a transplant, a cornea from a 71-year-old donor is likely to remain as healthy as a cornea from a donor half that age, and corneas from donors over 71 perform slightly less well but still remain healthy for most transplant recipients, according to a study funded by the National Eye Institute (NEI) and led by the UC Davis Health System Eye Center and the University of Cincinnati Eye Institut

27 Nov 2013

Researchers show how unusual properties of A3G protein help fight HIV infection

A collaborative team led by a Northeastern University professor may have altered the way we look at drug development for HIV by uncovering some unusual properties of a human protein called APOBEC3G.

27 Nov 2013

H1N1 virus killed more people globally than originally believed, confirms study

A research team consisting of more than 60 collaborators in 26 countries has estimated the global death toll from the 2009 outbreak of the H1N1 virus to be 10 times higher than the World Health Organization's count, which was based on laboratory-confirmed cases of this flu. The study, which appears online in PLOS Medicine, suggests that the pandemic virus caused up to 203,000 respiratory deaths around the world.

27 Nov 2013

Restoring helpful bacteria of the gut and intestines may treat patients with RCDI, find scientists

Scientists at the Institute for Genome Sciences at the University of Maryland School of Medicine and physicians at Sinai Hospital, Baltimore, MD, have found that restoring the normal, helpful bacteria of the gut and intestines may treat patients suffering from recurrent Clostridium difficile infections. Transplanting fecal matter of healthy donors into patients with recurrent C. difficile infection appears to restore normal bacterial composition and resolve infection.

27 Nov 2013

Participating in photovoice empowers women living with HIV to realize their strengths

Having human immunodeficiency virus, the virus that causes AIDS, can create many challenges for individuals physically, socially and emotionally. A University of Missouri researcher found that participating in photovoice, a process by which individuals document their lives by taking pictures, empowered women living with HIV to realize their strengths in the midst of their struggles.

27 Nov 2013

Isis Pharmaceuticals commences Phase 1 study of ISIS-GSK3Rx for treatment of common viral infection

Isis Pharmaceuticals, Inc. announced today that it has initiated a Phase 1 study for ISIS-GSK3Rx and earned a $3 million milestone payment from GlaxoSmithKline.

27 Nov 2013

Disease/Infection News

Study brings effective hepatitis C cure closer to reality

Scientists design small synthetic molecules capable of blocking AIDS virus replication

Medical Research Council should do more in the development of gold standard for clinical trial design

Scientists identify new approach to fight malaria parasites

Pediatric dermatologists offer tips for treating skin ailments

PLOS and DNDi to launch collection of neglected tropical diseases at 10-year anniversary of DNDi

Researchers identify protein in malaria that is inhibited by newly discovered anti-malarial compounds

Findings highlight possible new approach to combat malaria

New NIH guidelines for managing opportunistic infections in children with HIV

HIV test for new inmates may not yield new diagnoses, says study

Study highlights unique barriers for African Americans with hypertension

European research project examines toxicity factor to fight AIDS

University of Wisconsin Hospital and Clinics recognized with 2013 Partnership in Prevention Award

Nonabsorbable antibiotics effective in eradicating CRE colonization

Study shows most corneal transplants have remarkable longevity regardless of donor age

Researchers show how unusual properties of A3G protein help fight HIV infection

H1N1 virus killed more people globally than originally believed, confirms study

Restoring helpful bacteria of the gut and intestines may treat patients with RCDI, find scientists

Participating in photovoice empowers women living with HIV to realize their strengths

Isis Pharmaceuticals commences Phase 1 study of ISIS-GSK3Rx for treatment of common viral infection

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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