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Researchers Study how Marburg virus and host protein interaction help in developing inhibitors of virus

A protein that normally protects cells from environmental stresses has been shown to interact Marburg virus VP24, allowing the deadly Marburg virus to live longer and replicate better, according to a cell culture study led by scientists at the Icahn School of Medicine at Mount Sinai.

14 Mar 2014

TFDA approves TaiGen's Taigexyn NDA for treatment of community-acquired bacterial pneumonia

TaiGen Biotechnology Company, Limited today announced that the Taiwan Food and Drug Administration has approved the new drug application (NDA) of Taigexyn (nemonoxacin) oral formulation (500 mg) for the treatment of community-acquired bacterial pneumonia (CAP). With this NDA approval, Taiwan is the first region to grant marketing approval to Taigexyn.

13 Mar 2014

New research raises hopes of new class of drugs to combat antibiotic resistant infections

New research has found some compounds effective in blocking the proliferation of certain bacteria, raising hopes of a new class of drugs to combat antibiotic resistant infections

13 Mar 2014

Programs for heterosexuals who use drugs linked with subsequent lower rates of AIDS incidence

Although community network studies show that sexual relationships occur between members of "risk groups" -- men who have sex with other men (MSM), people who inject drugs (PWID), non-injection drug users (NIDU) -- and heterosexuals, researchers at New York University's Center for Drug Use and HIV Research (CDUHR) note that little research has been done to help explain how HIV epidemics and programs in one population affect others and how to reduce the risks of transmission.

13 Mar 2014

Notre Dame biologists awarded $23M research grant to prevent malaria and dengue fever

Notre Dame biologists Nicole Achee and Neil Lobo are leaders of an international $23 million research grant from the Bill & Melinda Gates Foundation. Their five-year project will generate the data required to show the effectiveness of a new paradigm in mosquito control -spatial repellency - for the prevention of two important mosquito-borne diseases: malaria and dengue fever.

13 Mar 2014

Gut bacteria and blood cell development relationship helps immune system fight infection

The human relationship with microbial life is complicated. At almost any supermarket, you can pick up both antibacterial soap and probiotic yogurt during the same shopping trip.

13 Mar 2014

Bacterium and fungus partner to cause painful form of tooth decay in preschool children

Early childhood caries, a highly aggressive and painful form of tooth decay that frequently occurs in preschool children, especially from backgrounds of poverty, may result from a nefarious partnership between a bacterium and a fungus, according to a paper published ahead of print in the journal Infection and Immunity.

13 Mar 2014

Parasites in human are most likely to interact via food source

Over 1,400 species of parasites - viruses, bacteria, fungi, intestinal worms and protozoa - are able to infect humans. In most cases, the right medicine against a parasite cures the patient.

12 Mar 2014

UNIGE discovers new class of molecules toxic for Plasmodium pathogen

The malaria parasite is particularly pernicious since it is built to develop resistance to treatments. The lack of new therapeutic approaches also contributes to the persistence of this global scourge.

12 Mar 2014

Experimental drugs offer hope for people with hepatitis C

Patrizia Cazzaniga had heard the horror stories about early treatments for hepatitis C - multiple daily pills and weekly shots for up to a year, side effects that could be debilitating, and a cure rate of only about 40 percent.

11 Mar 2014

Researchers suggest potential treatment target for HCMV infection

Discovering where a common virus hides in the body has been a long-term quest for scientists. Up to 80 percent of adults harbor the human cytomegalovirus (HCMV), which can cause severe illness and death in people with weakened immune systems.

11 Mar 2014

One person's unique ability provides key insights into immune response to fight HIV

One person's unique ability to fight HIV has provided key insights into an immune response that researchers now hope to trigger with a vaccine, according to findings reported by a team that includes Duke Medicine scientists.

11 Mar 2014

Controlled TB vaccine trial designed to study prevention of Mtb infection by vaccination

Aeras today announced the initiation of the first randomized, controlled tuberculosis (TB) vaccine trial designed to study prevention of Mycobacterium tuberculosis (Mtb) infection by vaccination.

11 Mar 2014

Study gives insights into designing new drugs to fight infections

Efforts to combat bacteria’s growing resistance to antibiotics could be helped by a key discovery about the complex processes that enable bugs to thrive.

10 Mar 2014

Findings suggest that IBS is linked to detectable gut microbiota alterations

Irritable bowel syndrome (IBS) belongs to the most widespread diseases in Western countries, causing up to sixty per cent of the workload of gastrointestinal physicians. One of the most frequent symptoms of IBS is bloating, which reduces quality of life considerably as patients perceive it as particularly bothersome.

10 Mar 2014

Inconsistent definition and management of deadly pathogens could contribute to spread of infections

Infection control practices for detecting and treating patients infected with emerging multidrug-resistant gram-negative bacteria (MDR-GNB) vary significantly between hospitals.

10 Mar 2014

Warmer temperatures allow malaria to spread to higher elevations

Malaria, a mosquito-borne disease, infects more than 300 million people each year. Cooler highland regions have historically provided havens from malaria, but it has been predicted that the disease could be especially sensitive to climate change, since both the Plasmodium parasites that cause it and the Anopheles mosquitoes that spread it thrive at warm temperatures. The potential impact of global warming on the worldwide incidence of malaria has been debated for more than two decades.

7 Mar 2014

New method of protecting women from transmission of HIV is safe

Findings of an early phase clinical trial at the University of Alabama at Birmingham suggest that a possible new method of protecting women from the transmission of HIV is safe.

7 Mar 2014

Researchers look at health threat to pregnant women with history of Kawasaki disease

In the first study of its type, researchers at the University of California, San Diego School of Medicine have looked at the health threat to pregnant women with a history of Kawasaki disease (KD), concluding that the risks are low with informed management and care.

7 Mar 2014

Boehringer Ingelheim reports results from SVR12 Phase 3 trial in patients with HCV/HIV co-infection

Today Boehringer Ingelheim announced results from STARTVerso4 in patients with HCV/HIV co-infection. Hepatitis C viral cure 12 weeks after the conclusion of treatment (SVR12) was achieved by 72% of all patients in the trial. Patients were enrolled in either 120mg or 240mg faldaprevir dose groups.

6 Mar 2014

Disease/Infection News

Researchers Study how Marburg virus and host protein interaction help in developing inhibitors of virus

TFDA approves TaiGen's Taigexyn NDA for treatment of community-acquired bacterial pneumonia

New research raises hopes of new class of drugs to combat antibiotic resistant infections

Programs for heterosexuals who use drugs linked with subsequent lower rates of AIDS incidence

Notre Dame biologists awarded $23M research grant to prevent malaria and dengue fever

Gut bacteria and blood cell development relationship helps immune system fight infection

Bacterium and fungus partner to cause painful form of tooth decay in preschool children

Parasites in human are most likely to interact via food source

UNIGE discovers new class of molecules toxic for Plasmodium pathogen

Experimental drugs offer hope for people with hepatitis C

Researchers suggest potential treatment target for HCMV infection

One person's unique ability provides key insights into immune response to fight HIV

Controlled TB vaccine trial designed to study prevention of Mtb infection by vaccination

Study gives insights into designing new drugs to fight infections

Findings suggest that IBS is linked to detectable gut microbiota alterations

Inconsistent definition and management of deadly pathogens could contribute to spread of infections

Warmer temperatures allow malaria to spread to higher elevations

New method of protecting women from transmission of HIV is safe

Researchers look at health threat to pregnant women with history of Kawasaki disease

Boehringer Ingelheim reports results from SVR12 Phase 3 trial in patients with HCV/HIV co-infection

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