Disease/Infection News

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Study characterizes mechanisms of pathogenesis, transmission of bacteria that cause gonorrhea

Researchers have come a step closer to understanding how gonorrhea infections are transmitted. When Neisseria gonorrhoeae, the bacteria responsible for gonorrhea, are exposed to seminal plasma, the liquid part of semen containing secretions from the male genital tract, they can more easily move and start to colonize.

4 Mar 2014

AbbVie's PEARL-III study meets primary, secondary endpoints in patients with chronic GT1b HCV infection

The first detailed results from AbbVie's pivotal phase III study, PEARL-III, were presented today as part of the 21st Conference on Retroviruses and Opportunistic Infections (CROI) press conference and will also be presented as a late-breaker at the conference on March 4.

4 Mar 2014

Arrowhead receives approval to initiate Phase 2a clinical trial of ARC-520 for chronic HBV infection

Arrowhead Research Corporation (NASDAQ: ARWR), a biopharmaceutical company developing targeted RNAi therapeutics, today announced that it received regulatory approval to begin a Phase 2a clinical trial of ARC-520, its RNAi-based drug candidate for the treatment of chronic hepatitis B virus (HBV) infection.

4 Mar 2014

New findings point the way toward potentially more effective HIV vaccine

In an advance for HIV vaccine research, a scientific team has discovered how the immune system makes a powerful antibody that blocks HIV infection of cells by targeting a site on the virus called V1V2.

4 Mar 2014

Neuroscientists unlock a piece of puzzle in fight against Lou Gehrig's disease

Keck School of Medicine of USC neuroscientists have unlocked a piece of the puzzle in the fight against Lou Gehrig's disease, a debilitating neurological disorder that robs people of their motor skills.

4 Mar 2014

Photoreactive compounds open new routes to treatment of neurological diseases

Photoreactive compounds developed by scientists of Ludwig-Maximilians-Universitaet (LMU) in Munich directly modulate nerve-cell function, and open new routes to the treatment of neurological diseases, including chronic pain and certain types of visual impairment.

3 Mar 2014

Scientists map key elements of immune overreaction triggered by influenza virus infection

Scientists at The Scripps Research Institute (TSRI) have mapped key elements of a severe immune overreaction—a "cytokine storm"—that can both sicken and kill patients who are infected with certain strains of flu virus.

3 Mar 2014

3D structure of enzyme helps defend against bacteria

An essential weapon in the body's fight against infection has come into sharper view. Researchers at Princeton University have discovered the 3D structure of an enzyme that cuts to ribbons the genetic material of viruses and helps defend against bacteria.

3 Mar 2014

Deficient hygiene routines make it difficult to eradicate multi-resistant bacterium

A previously unknown multi-resistant bacterium has been sticking around at a Swedish University Hospital for ten years.

3 Mar 2014

Bayer HealthCare joins NORD to promote awareness of Rare Disease Day

Bayer HealthCare is joining the National Organization for Rare Disorders (NORD) and others in raising awareness of Rare Disease Day, which is being celebrated today around the world.

3 Mar 2014

Scientists find certain species of nontuberculous mycobacteria in water that cause infection in humans

Brisbane's water supply has been found to contain disease carrying bugs which can be directly linked to infections in some patients, according to a new study by QUT.

3 Mar 2014

Global initiatives underscore shire's long-term commitment to rare disease community

Shire plc (LSE: SHP, NASDAQ: SHPG) today announced its support of Rare Disease Day and invites others to join them in its continued commitment to the rare disease community.

3 Mar 2014

Scientists develop new anti-viral drugs that may be effective against flu virus

New analysis of the influenza A virus by scientists at the University of Hertfordshire shows potential for developing new anti-viral drugs which are more likely to be universally effective against the flu virus originating from avian, swine or human virus strains.

28 Feb 2014

NPR correspondent to deliver keynote address at Seattle Biomed's annual event

Seattle BioMed today announced that Jason Beaubien, global health and development correspondent of National Public Radio (NPR), will deliver the keynote address at the Passport to Global Health Celebration on March 5.

28 Feb 2014

TSRI scientists describe severe immune overreaction caused by flu infections

Scientists at The Scripps Research Institute have mapped key elements of a severe immune overreaction—a “cytokine storm”—that can both sicken and kill patients who are infected with certain strains of flu virus.

28 Feb 2014

Researchers develop new method for rapid detection of anthrax

Shortly following the 9/11 terror attack in 2001, letters containing anthrax spores were mailed to news outlets and government buildings killing five people and infecting 17 others.

28 Feb 2014

Astellas' isavuconazole receives QIDP designation from FDA for zygomycosis treatment

Astellas Pharma Global Development, Inc., a subsidiary of Tokyo-based Astellas Pharma Inc., announced today that the U.S. Food and Drug Administration designated isavuconazole as a Qualified Infectious Disease Product (QIDP) for the treatment of invasive mucormycosis (also known as zygomycosis), a life-threatening invasive fungal infection caused by certain emerging molds.

27 Feb 2014

Study: Direct camel-to-human transmission of MERS virus is possible in Saudi Arabia

An estimated three-quarters of camels recently surveyed in Saudi Arabia have evidence of infection with the Middle East Respiratory Syndrome coronavirus (MERS-CoV), the virus responsible for human cases of MERS.

27 Feb 2014

Simple change in hospital laboratory reports may improve antibiotic prescribing practices

A simple change in how the hospital laboratory reports test results may help improve antibiotic prescribing practices and patient safety, according to a pilot, proof-of-concept study published in Clinical Infectious Diseases and now available online.

27 Feb 2014

LA BioMed researchers awarded NIH grant to pursue new approaches for treating MRSA

With antibiotic resistant infections on the rise and a scarce pipeline of novel drugs to combat them, researchers at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center are pursuing entirely new approaches to meet the challenge of drug-resistant infections by taming microbes rather than killing them.

27 Feb 2014

Disease/Infection News

Study characterizes mechanisms of pathogenesis, transmission of bacteria that cause gonorrhea

AbbVie's PEARL-III study meets primary, secondary endpoints in patients with chronic GT1b HCV infection

Arrowhead receives approval to initiate Phase 2a clinical trial of ARC-520 for chronic HBV infection

New findings point the way toward potentially more effective HIV vaccine

Neuroscientists unlock a piece of puzzle in fight against Lou Gehrig's disease

Photoreactive compounds open new routes to treatment of neurological diseases

Scientists map key elements of immune overreaction triggered by influenza virus infection

3D structure of enzyme helps defend against bacteria

Deficient hygiene routines make it difficult to eradicate multi-resistant bacterium

Bayer HealthCare joins NORD to promote awareness of Rare Disease Day

Scientists find certain species of nontuberculous mycobacteria in water that cause infection in humans

Global initiatives underscore shire's long-term commitment to rare disease community

Scientists develop new anti-viral drugs that may be effective against flu virus

NPR correspondent to deliver keynote address at Seattle Biomed's annual event

TSRI scientists describe severe immune overreaction caused by flu infections

Researchers develop new method for rapid detection of anthrax

Astellas' isavuconazole receives QIDP designation from FDA for zygomycosis treatment

Study: Direct camel-to-human transmission of MERS virus is possible in Saudi Arabia

Simple change in hospital laboratory reports may improve antibiotic prescribing practices

LA BioMed researchers awarded NIH grant to pursue new approaches for treating MRSA

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

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